269 research outputs found
Lipid droplet detection by the cavity perturbation method
There are currently no point-of-care diagnosis strategies available to indicate the presence of neoplasmic growth. This research aims to develop a novel diagnostic strategy based on detecting TAG accumulation in cells. This element of the research is a preliminary experiment to prove the concept of detecting TAG lipid droplets in YEPD media. It was found that a change in mono-unsaturated concentration can be detected by the frequency shift in a resonant cavity. The dielectric constant of TAG vegetable oils was calculated at 2.34-2.39. It was also found that concentrations of lipid droplet can be differentiated up to 5% (v/v)
Langevin equation with scale-dependent noise
A new wavelet based technique for the perturbative solution of the Langevin
equation is proposed. It is shown that for the random force acting in a limited
band of scales the proposed method directly leads to a finite result with no
renormalization required. The one-loop contribution to the Kardar-Parisi-Zhang
equation Green function for the interface growth is calculated as an example.Comment: LaTeX, 5 page
Dispersion Coefficients by a Field-Theoretic Renormalization of Fluid Mechanics
We consider subtle correlations in the scattering of fluid by randomly placed
obstacles, which have been suggested to lead to a diverging dispersion
coefficient at long times for high Peclet numbers, in contrast to finite
mean-field predictions. We develop a new master equation description of the
fluid mechanics that incorporates the physically relevant fluctuations, and we
treat those fluctuations by a renormalization group procedure. We find a finite
dispersion coefficient at low volume fraction of disorder and high Peclet
numbers.Comment: 4 pages, 1 figure; to appear in Phys. Rev. Let
Defect generation and deconfinement on corrugated topographies
We investigate topography-driven generation of defects in liquid crystals
films coating frozen surfaces of spatially varying Gaussian curvature whose
topology does not automatically require defects in the ground state. We study
in particular disclination-unbinding transitions with increasing aspect ratio
for a surface shaped as a Gaussian bump with an hexatic phase draped over it.
The instability of a smooth ground state texture to the generation of a single
defect is also discussed. Free boundary conditions for a single bump are
considered as well as periodic arrays of bumps. Finally, we argue that defects
on a bump encircled by an aligning wall undergo sharp deconfinement transitions
as the aspect ratio of the surface is lowered.Comment: 24 page
Multiscale theory of turbulence in wavelet representation
We present a multiscale description of hydrodynamic turbulence in
incompressible fluid based on a continuous wavelet transform (CWT) and a
stochastic hydrodynamics formalism. Defining the stirring random force by the
correlation function of its wavelet components, we achieve the cancellation of
loop divergences in the stochastic perturbation expansion. An extra
contribution to the energy transfer from large to smaller scales is considered.
It is shown that the Kolmogorov hypotheses are naturally reformulated in
multiscale formalism. The multiscale perturbation theory and statistical
closures based on the wavelet decomposition are constructed.Comment: LaTeX, 27 pages, 3 eps figure
Statistical Description of Acoustic Turbulence
We develop expressions for the nonlinear wave damping and frequency
correction of a field of random, spatially homogeneous, acoustic waves. The
implications for the nature of the equilibrium spectral energy distribution are
discussedComment: PRE, Submitted. REVTeX, 16 pages, 3 figures (not included) PS Source
of the paper with figures avalable at
http://lvov.weizmann.ac.il/onlinelist.htm
Notes about Passive Scalar in Large-Scale Velocity Field
We consider advection of a passive scalar theta(t,r) by an incompressible
large-scale turbulent flow. In the framework of the Kraichnan model the whole
PDF's (probability distribution functions) for the single-point statistics of
theta and for the passive scalar difference theta(r_1)-theta(r_2) (for
separations r_1-r_2 lying in the convective interval) are found.Comment: 19 pages, RevTe
Stability of scaling regimes in developed turbulence with weak anisotropy
The fully developed turbulence with weak anisotropy is investigated by means
of renormalization group approach (RG) and double expansion regularization for
dimensions . Some modification of the standard minimal substraction
scheme has been used to analyze stability of the Kolmogorov scaling regime
which is governed by the renormalization group fixed point. This fixed point is
unstable at ; thus, the infinitesimally weak anisotropy destroyes above
scaling regime in two-dimensional space. The restoration of the stability of
this fixed point, under transition from to has been demonstrated
at borderline dimension . The results are in qualitative agreement
with ones obtained recently in the framework of the usual analytical
regularization scheme.Comment: 23 pages, 2 figure
Hope, optimism and survival in a randomized trial of chemotherapy for metastatic colorectal cancer
Purpose: Psychological responses to cancer are widely believed to affect survival. We investigated associations between hope, optimism, anxiety, depression, health utility and survival in patients starting first line chemotherapy for metastatic colorectal cancer. Methods: 429 subjects with metastatic colorectal cancer in a randomised controlled trial of chemotherapy, completed baseline questionnaires assessing: hopefulness, optimism, anxiety and depression and health utility. Hazard ratios (HR) and P-values were calculated with Cox models for overall survival (OS) and progression-free survival (PFS) in univariable and multivariable analyses. Results: Median follow-up was 31 months. Univariable analyses showed that OS was associated negatively with depression (HR 2.04, P<0.001), and positively with health utility (HR 0.56, P<0.001) and hopefulness (HR 0.75, P=0.013). In multivariable analysis, OS was also associated negatively with depression (HR 1.72, P<0.001), and positively with health utility (HR 0.73, P=0.014), but not with optimism, anxiety or hopefulness. PFS was not associated with hope, optimism, anxiety or depression in any analyses. Conclusions: Depression and health utility, but not optimism, hope, or anxiety were associated with survival after controlling for known prognostic factors in patients with advanced colorectal cancer. Further research is required to understand the nature of the relationship between depression and survival. If a causal mechanism is identified, this may lead to interventional possibilities
Numerical study of the spherically-symmetric Gross-Pitaevskii equation in two space dimensions
We present a numerical study of the time-dependent and time-independent
Gross-Pitaevskii (GP) equation in two space dimensions, which describes the
Bose-Einstein condensate of trapped bosons at ultralow temperature with both
attractive and repulsive interatomic interactions. Both time-dependent and
time-independent GP equations are used to study the stationary problems. In
addition the time-dependent approach is used to study some evolution problems
of the condensate. Specifically, we study the evolution problem where the trap
energy is suddenly changed in a stable preformed condensate. In this case the
system oscillates with increasing amplitude and does not remain limited between
two stable configurations. Good convergence is obtained in all cases studied.Comment: 9 latex pages, 7 postscript figures, To appear in Phys. Rev.
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