150 research outputs found

    Exploring Design Space For An Integrated Intelligent System

    Get PDF
    Understanding the trade-offs available in the design space of intelligent systems is a major unaddressed element in the study of Artificial Intelligence. In this paper we approach this problem in two ways. First, we discuss the development of our integrated robotic system in terms of its trajectory through design space. Second, we demonstrate the practical implications of architectural design decisions by using this system as an experimental platform for comparing behaviourally similar yet architecturally different systems. The results of this show that our system occupies a "sweet spot" in design space in terms of the cost of moving information between processing components

    Ballistic Impact Mitigation Pad

    Get PDF
    In our senior design project we have decided to work under Dr. Jon Gerhardt on creating a gel pad to mitigate blunt force behind bulletproof vests. Extensive research on injury, materials, manufacturing methods, and NIJ standards was completed during this project. Through the use of advanced modeling software and additive manufacturing, we prototyped a functioning pad to test and compare to a pad that is currently available in today\u27s market. The results proved to be very successful, but there are many areas to improve upon down the road

    A Modular Functional Electrical Stimulation (FES) System for Gait Assistance in Pediatric Cerebral Palsy

    Get PDF
    Foot drop, the inability to lift the forefoot during gait, is a common symptom of disorders such as diabetes, stroke, spina bifida, and cerebral palsy. This condition makes walking difficult and unsafe, often resulting in stumbles and falls due to lack of ground clearance. The current standard of care is orthotic bracing, which presents donning and doffing challenges, restricts ankle motion, and contributes to social stigma in many parts of the world. Functional electrical stimulation (FES) is an alternative approach which uses small amounts of electrical current delivered through skin-surface electrodes to stimulate peripheral nerves, thus generating muscle contraction and ultimately functional movement of a human limb. When packaged in a wearable device with onboard sensors capable of detecting gait phase, stimulation current can be applied to the lower leg to cause the foot to lift during the swing phase of gait. While several FES foot-drop systems are commercially available, they cost upward of $13,000 and provide a level of adjustability and complexity not needed for many conditions. The Messiah FES team is working to develop a low-cost, portable, easy-to-use, and durable electrical stimulation device to restore legged ambulation to children with mobility impairments resulting from cerebral palsy, spina bifida, and other conditions with similar effects. Our clinical partner is CURE Ethiopia, with our primary contacts being Dr. Tim Nunn and Dr. Laurence Wicks at the CURE Ethiopia Children\u27s Hospital in Addis Ababa, Ethiopia. Funding for this work provided by The Collaboratory for Strategic Partnerships and Applied Research.https://mosaic.messiah.edu/engr2022/1007/thumbnail.jp

    The prevention and treatment of glucocorticoid-induced osteopaenia in juvenile rheumatic disease : a randomised double-blind controlled trial

    Get PDF
    Background: Children and young people (CYP) with chronic rheumatic conditions; Juvenile Idiopathic Arthritis, Juvenile Systemic Lupus Erythematosus, Juvenile Dermatomyositis and Juvenile Vasculitis, treated with steroids, have low bone density, increased fracture risk and are likely to have suboptimal peak bone mass. There is currently no evidence base for the management of steroid-induced bone loss in children with rheumatic diseases. Methods: We undertook a multi-centre double dummy double-blind randomised placebo controlled trial to investigate whether the bisphosphonate risedronate was superior to alfacalcidol or calcium and vitamin D supplementation in the prevention and treatment of steroid-induced osteopaenia in these children. Patients were stratified and randomised in a 1:1 ratio, into: placebo; alfacalcidol; risedronate. The primary outcome was the change in lumbar spine bone mineral density z score (LSaBMDz) measured by dual energy x-ray absorptiometry at one year. Secondary outcome was fracture rate. Results: Two hundred and seventeen patients were recruited to the study. Seventy seven placebo, 71 alfacalcidol, and 69 risedronate. Highly statistically significant differences were observed in the change in LSaBMDz between the placebo and risedronate groups; 0.274, 95% CI (0.061, 0.487) (p < 0.001) and between the risedronate and the alfacalcidol groups; 0.326 95% CI (0.109, 0.543) (p < 0.001). The difference observed between the alfacalcidol and placebo group was not statistically significant. Highly statistically significant differences were seen in the change in Total Body Less Head aBMD-Z Score between the placebo and risedronate groups (p < 0.01) but not between the alfacalcidol and risedronate groups. No significant differences in fracture frequency, adverse or serious adverse reactions were observed between the groups. Conclusions: Children and adolescents receiving steroids for rheumatic diseases benefit from prophylactic treatment with bisphosphonates to increase LSaBMD. Alfacalcidol is ineffective
    • …
    corecore