1,917 research outputs found
Metastability of non-reversible mean-field Potts model with three spins
We examine a non-reversible, mean-field Potts model with three spins on a set
with points. Without an external field, there are three
critical temperatures and five different metastable regimes. The analysis can
be extended by a perturbative argument to the case of small external fields. We
illustrate the case of large external fields with some phenomena which are not
present in the absence of external field.Comment: 34 pages, 12 figure
A study on the interacting Ricci dark energy in gravity
The present work reports study on the interacting Ricci dark energy in a
modified gravity theory named gravity. The specific model (proposed by R. Myrzakulov, arXiv:1205.5266v2) is considered here. For
this model we have observed a quintom-like behavior of the equation of state
(EoS) parameter and a transition from matter dominated to dark energy density
has been observed through fraction density evolution. The statefinder
parameters reveal that the model interpolates between dust and CDM
phases of the universe.Comment: 12 pages, 5 figure
The Paleoproterozoic Chibaisong Mafic-Ultramafic Intrusion and Cu-Ni Deposit, North China Craton: SHRIMP Zircon U-Pband Re-Os Geochronology and Geodynamic Implications
published_or_final_versio
Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells
Protein array technology is a powerful platform for the simultaneous determination of the expression levels of a number of proteins as well as post-translational modifications such as phosphorylation. Here, we screen and report for the first time, the dominant signaling cascades and apoptotic mediators during the course of cadmium (Cd)-induced cytotoxicity in human bronchial epithelial cells (BEAS-2B) by antibody array analyses. Proteins from control and Cd-treated cells were captured on Proteome Profiler™ Arrays for the parallel determination of the relative levels of protein phosphorylation and proteins associated with apoptosis. Our results indicated that the p38 MAPK- and JNK-related signal transduction pathways were dramatically activated by Cd treatment. Cd potently stimulates the phosphorylations of p38α (MAPK14), JNK1/2 (MAPK8/9), and JUN; while the phosphorylations of Akt1, ERK1/2 (MAPK3/1), GSK3β, and mTOR were suppressed. Moreover, there was an induction of proapoptotic protein BAX, release of cytochrome c (CYCS) from mitochondria, activation of caspase-3/9 (CASP3/9); as well as decreased expression of cell cycle checkpoint proteins (TP53, p21, and p27) and several inhibitors of apoptosis proteins (IAPs) [including cIAP-1/2 (BIRC2/3), XIAP (BIRC4), and survivin (BIRC5)]. Pretreatment of cells with the thiol antioxidant glutathione or p38 MAPK/JNK inhibitors before Cd treatment effectively abrogated ROS activation of p38 MAPK/JNK pathways and apoptosis-related proteins. Taken together, our results demonstrate that Cd causes oxidative stress-induced apoptosis; and the p38 MAPK/JNK and mitochondrial pathways are more importantly participated for signal transduction and the induction of apoptosis in Cd-exposed human lung cells.published_or_final_versio
Oxidative coupling between C(sp2)-H and C(sp3)-H bonds of indoles and cyclic ethers/cycloalkanes
2015-2016 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
Tactical Voting in Plurality Elections
How often will elections end in landslides? What is the probability for a
head-to-head race? Analyzing ballot results from several large countries rather
anomalous and yet unexplained distributions have been observed. We identify
tactical voting as the driving ingredient for the anomalies and introduce a
model to study its effect on plurality elections, characterized by the relative
strength of the feedback from polls and the pairwise interaction between
individuals in the society. With this model it becomes possible to explain the
polarization of votes between two candidates, understand the small margin of
victories frequently observed for different elections, and analyze the polls'
impact in American, Canadian, and Brazilian ballots. Moreover, the model
reproduces, quantitatively, the distribution of votes obtained in the Brazilian
mayor elections with two, three, and four candidates.Comment: 7 pages, 4 figure
Reduction of covalently closed circular DNA with long-term nucleos(t)ide analogue treatment in chronic hepatitis B
postprin
Improving slurryability, rheology, and stability of slurry fuel from blending petroleum coke with lignite
Fracturing ranked surfaces
Discretized landscapes can be mapped onto ranked surfaces, where every
element (site or bond) has a unique rank associated with its corresponding
relative height. By sequentially allocating these elements according to their
ranks and systematically preventing the occupation of bridges, namely elements
that, if occupied, would provide global connectivity, we disclose that bridges
hide a new tricritical point at an occupation fraction , where
is the percolation threshold of random percolation. For any value of in the
interval , our results show that the set of bridges has a
fractal dimension in two dimensions. In the limit , a self-similar fracture is revealed as a singly connected line
that divides the system in two domains. We then unveil how several seemingly
unrelated physical models tumble into the same universality class and also
present results for higher dimensions
Efficient coupling of photons to a single molecule and the observation of its resonance fluorescence
Single dye molecules at cryogenic temperatures display many spectroscopic
phenomena known from free atoms and are thus promising candidates for
fundamental quantum optical studies. However, the existing techniques for the
detection of single molecules have either sacrificed the information on the
coherence of the excited state or have been inefficient. Here we show that
these problems can be addressed by focusing the excitation light near to the
absorption cross section of a molecule. Our detection scheme allows us to
explore resonance fluorescence over 9 orders of magnitude of excitation
intensity and to separate its coherent and incoherent parts. In the strong
excitation regime, we demonstrate the first observation of the Mollow triplet
from a single solid-state emitter. Under weak excitation we report the
detection of a single molecule with an incident power as faint as 150 attoWatt,
paving the way for studying nonlinear effects with only a few photons.Comment: 6 figure
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