4,728 research outputs found

    Research on the Case of Art Therapy and Cognition of Autistic Children

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    Due to congenital brain damage, autistic children suffer from difficulties in overall development, especially in interpersonal relation, language and behavior. Many scholars try to understand the inner world of autistic children through various treatments, but only painting, the most primitive language for children, is also the most direct way to express the autistic children’s mind. Therefore, there seems to be a certain degree of corresponding relation between artistic creation and message expression, but artistic creation is actually a complex mental activity, and it is difficult to understand the meaning of message in a simple model. This study explores the communication modes in addition to language based on the case of three children’s paintings in the “Gallery for Little Friends” initiated by Tencent Charity Foundation, whose main purpose is to develop an alternative way to communicate with autistic children, let us know, interpret and evaluate through their paintings, and then take appropriate actions to transform the messages in the paintings to concrete actions and measures, realize the goal of helping autistic children’s oral expression, and try to interpret the inner world of autistic children with painting as a medium

    A Diffusion model for POI recommendation

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    Next Point-of-Interest (POI) recommendation is a critical task in location-based services that aim to provide personalized suggestions for the user's next destination. Previous works on POI recommendation have laid focused on modeling the user's spatial preference. However, existing works that leverage spatial information are only based on the aggregation of users' previous visited positions, which discourages the model from recommending POIs in novel areas. This trait of position-based methods will harm the model's performance in many situations. Additionally, incorporating sequential information into the user's spatial preference remains a challenge. In this paper, we propose Diff-POI: a Diffusion-based model that samples the user's spatial preference for the next POI recommendation. Inspired by the wide application of diffusion algorithm in sampling from distributions, Diff-POI encodes the user's visiting sequence and spatial character with two tailor-designed graph encoding modules, followed by a diffusion-based sampling strategy to explore the user's spatial visiting trends. We leverage the diffusion process and its reversed form to sample from the posterior distribution and optimized the corresponding score function. We design a joint training and inference framework to optimize and evaluate the proposed Diff-POI. Extensive experiments on four real-world POI recommendation datasets demonstrate the superiority of our Diff-POI over state-of-the-art baseline methods. Further ablation and parameter studies on Diff-POI reveal the functionality and effectiveness of the proposed diffusion-based sampling strategy for addressing the limitations of existing methods

    N 1,N 2-Bis(6-methyl-2-pyrid­yl)formamidine

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    In the crystal structure of the title mol­ecule, C13H14N4, the two pyridyl rings are not coplanar but twisted about the C—N bond with an inter­planar angle of 71.1 (1)°. In the crystal, the mol­ecules form dimers, situated on crystallographic centres of inversion, which are connected via a pair of N—H⋯N hydrogen bonds. C—H⋯π-electron ring inter­actions are also present in the crystal structure. The title mol­ecule adopts an s–cis–anti–s–cis conformation in the solid state

    Effects of Stress Evolution Process on the Thermal Stability of Thin Accretion Discs

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    The stress evolution process is taken into account in the linear stability analysis of standard thin accretion discs. We find that the growth rate of thermally unstable modes can decrease significantly owing to the stress delay, which may help to understand the quasi-periodic variability of GRS 1915+105. We also discuss possible application of stress evolution to the stability of Shapiro-Lightman-Eardley disc.Comment: 5 pages, 2 figures, accepted by MNRA

    Liquid Crystal Display with Different Twisting Directions of Liquid Crystal Molecules

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    A liquid crystal display includes a first alignment film having a first alignment direction, a second alignment film having a second alignment direction, and a liquid crystal layer having liquid crystal molecules between the first and second alignment films. The liquid crystal layer is doped with a chiral material that tends to induce a first twist in directors of the liquid crystal molecules when an electric field is applied to the liquid crystal layer. The first and second alignment films have orientations that tends to induce a second twist in the directors when an electric field is applied to the liquid crystal layer, in which the direction of the first twist is different from the direction of the second twist

    The role of extravillous trophoblasts and uterine NK cells in vascular remodeling during pregnancy

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    Successful embryo implantation requires both a receptive endometrium and competent blastocysts. After implantation, the maternal decidua undergoes a series of changes, including uterine spiral artery (SA) remodeling to accommodate the fetus and provide nutrients and oxygen for the fetus to survive. Uterine spiral arteries transform from small-diameter, high-resistance arteries to large-diameter and low-resistance arteries during pregnancy. This transformation includes many changes, such as increased permeability and dilation of vessels, phenotypic switching and migration of vascular smooth muscle cells (VSMCs), transient loss of endothelial cells (ECs), endovascular invasion of extravillous trophoblasts (EVTs), and presence of intramural EVT, which are regulated by uterine NK (uNK) cells and EVTs. In this review, we mainly focus on the separate and combined roles of uNK cells and EVTs in uterine SA remodeling in establishing and maintaining pregnancy. New insight into related mechanisms will help us better understand the pathogenesis of pregnancy complications such as recurrent pregnancy loss (RPL) and preeclampsia (PE)
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