1,494 research outputs found

    The EU’s Trade Policy in the Doha Development Agenda – An Interim Assessment on Rules Negotiations

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    At Doha Ministerial Conference in 2001, WTO members agreed to launch new trade negotiations on a range of subjects and other work, including issues concerning the implementation of the present agreements. Various issues in the WTO Doha Development Agenda were dealt with in the form of ‘single undertaking’ which include the trade remedy rules, i.e., anti-dumping and subsidies rules. The EU, being the largest regional economy in the world, was no doubt a heavyweight in the Doha multilateral trade negotiations and so was its trade policy of great weight. To date, the EU had put forward a total of 10 submissions to clarify and improve the AD Agreement and the SCM Agreement at the end of 2006, and the submissions revealed the EU’s attitude toward the Rules negoation; not aggressive but prudent and cautious. While Doha Round seemed doomed and gloomy, the EU, on the other hand, launched its new trade policy, the ‘Global Europe’ framework in 2006 pursuant to the goals set up by the conclusions of Lisbon European Council. The new EU’s trade policy is comprised of a wider array of trade issues, aiming at maintaining its global competitiveness, and in light of the growing fragmentation and complexity of the process of production and supply chains as well as the growth of major new economic actors, particularly in Asia, there was a need for a revision of the EU Trade Defence Instruments (TDI) . A “Green Paper” on TDI was thus drafted and presented for public consultation by the Commission at the end of 2006, which is intended to make sure EU TDI fit in the trend of globalization as well as the European multinational corporations' competiveness in the new economic context. This paper intends to explore if the possible trade policy adjustment in the EU TDI will also facilitate to resolve the discrepancy between the EU and its counterparts in the Rules negotiations and provide a solid basis for the conclusion thereof. Section II of the article presents the ongoing DDA negotiations, inter alia, Rules negotiations. Section III will probe the negotiation objective and issues that EU concern by examining its submissions to the Negotiating Group on Rules as well as its implementation assessment. The EU’s new trade policy, in particular, that on the newly released “Green Paper” on the TDI will also be analyzed in section IV. This paper concludes that the EU policy on TDI is expected to be adjusted toward a framework favorable to other economic operators, such as users and consumers. Whether the public consultation for “Green Paper” is a process of consensus building is still an argument. It is likely that EU delegate will narrow down the gap between the EU and other exporting-oriented members in the Rules negotiations should the revised TDI be expanded to a large extent

    A Spatial Investigation of ƒÐ-Convergence in China

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    Using techniques of spatial econometrics, this paper investigates ƒÐ-convergence of provincial real per capita gross domestic product (GDP) in China. The empirical evidence concludes that spatial dependence across regions is strong enough to distort the traditional measure of ƒÐ-convergence. This study focuses on the variation of per capita GDP that is dependent on the development processes of neighboring provinces and cities. This refinement of the conditional ƒÐ-convergence model specification allows for analysis of spatial dependence in the mean and variance. The corrected measure of ƒÐ-convergence in China indicates a lower level of dispersion in the economic development process. This implies a smaller divergence in real per capita GDP, although convergence across regions is still a challenging goal to achieve in the 2000s.ƒÐ-Convergence, Moran's index, spatial dependence, spatial lag

    Kinematic strategies for obstacle-crossing in older adults with mild cognitive impairment

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    IntroductionMild cognitive impairment (MCI) is considered a transitional stage between soundness of mind and dementia, often involving problems with memory, which may lead to abnormal postural control and altered end-point control when dealing with neuromechanical challenges during obstacle-crossing. The study aimed to identify the end-point control and angular kinematics of the pelvis-leg apparatus while crossing obstacles for both leading and trailing limbs.Methods12 patients with MCI (age: 66.7 ± 4.2 y/o; height: 161.3 ± 7.3 cm; mass: 62.0 ± 13.6 kg) and 12 healthy adults (age: 67.7 ± 2.9 y/o; height: 159.3 ± 6.1 cm; mass: 61.2 ± 12.0 kg) each walked and crossed obstacles of three different heights (10, 20, and 30% of leg length). Angular motions of the pelvis and lower limbs and toe-obstacle clearances during leading- and trailing-limb crossings were calculated. Two-way analyses of variance were used to study between-subject (group) and within-subject (obstacle height) effects on the variables. Whenever a height effect was found, a polynomial test was used to determine the trend. A significance level of α = 0.05 was set for all tests.ResultsPatients with MCI significantly increased pelvic anterior tilt, hip abduction, and knee adduction in the swing limb during leading-limb crossing when compared to controls (p < 0.05). During trailing-limb crossing, the MCI group showed significantly decreased pelvic posterior tilt, as well as ankle dorsiflexion in the trailing swing limb (p < 0.05).ConclusionPatients with MCI adopt altered kinematic strategies for successful obstacle-crossing. The patients were able to maintain normal leading and trailing toe-obstacle clearances for all tested obstacle heights with a specific kinematic strategy, namely increased pelvic anterior tilt, swing hip abduction, and knee adduction during leading-limb crossing, and decreased pelvic posterior tilt and swing ankle dorsiflexion during trailing-limb crossing. The current results suggest that regular monitoring of obstacle-crossing kinematics for reduced toe-obstacle clearance or any signs of changes in crossing strategy may be helpful for early detection of compromised obstacle-crossing ability in patients with single-domain amnestic MCI. Further studies using a motor/cognitive dual-task approach on the kinematic strategies adopted by multiple-domain MCI will be needed for a complete picture of the functional adaptations in such a patient group

    Promoter Polymorphism G-6A, which Modulates Angiotensinogen Gene Expression, Is Associated with Non-Familial Sick Sinus Syndrome

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    Background: It is well known that familial sick sinus syndrome (SSS) is caused by functional alterations of ion channels and gap junction. Limited information is available on the mechanism of age-related non-familial SSS. Although evidence shows a close link between arrhythmia and the renin-angiotensin system (RAS), it remains to be determined whether the RAS is involved in the pathogenesis of non-familial SSS. Methods: In this study, 113 patients with documented non-familial SSS and 125 controls were screened for angiotensinogen (AGT) and gap junction protein-connexin 40 (Cx40) promoter polymorphisms by gene sequencing, followed by an association study. A luciferase assay was used to determine the transcriptional activity of the promoter polymorphism. The interaction between nuclear factors and the promoter polymorphism was characterized by an electrophoretic mobility shift assay (EMSA). Results: Association study showed the Cx40 -44/+71 polymorphisms are not associated with non-familial SSS; however, it indicated that four polymorphic sites at positions -6, -20, -152, and -217 in the AGT promoter are linked to non-familial SSS. Compared to controls, SSS patients had a lower frequency of the G-6A AA genotype (OR 2.88, 95% CI 1.58–5.22, P = 0.001) and a higher frequency of the G allele at -6 position (OR 2.65, 95% CI 1.54–4.57, P = 0.0003). EMSA and luciferase assays confirmed that nucleotide G at position -6 modulates the binding affinity with nuclear factors and yields a lower transcriptional activity than nucleotide A (P,0.01). Conclusion: G-6A polymorphism, which modulates the transcriptional activity of the AGT promoter, may contribute to nonfamilial SSS susceptibility

    Study on Results of Public Construction Quality Inspection in Taiwan

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    The quality of public construction projects signals the degree of a nation\u27s development to the rest of the world. Any nation hoping to advertise its strength and competitiveness on a global scale aims to improve the quality of its public construction, which includes establishing and maintaining an effective public construction quality management system. This article discusses the current results of public construction quality inspections in Taiwan and is expected to improve the quality of Taiwan\u27s public construction, which may help the nation advance in international prestige and compete in international markets

    Altered neuronatin expression in the rat dorsal root ganglion after sciatic nerve transection

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    <p>Abstract</p> <p>Background</p> <p>Several molecular changes occur following axotomy, such as gene up-regulation and down-regulation. In our previous study using Affymetrix arrays, it was found that after the axotomy of sciatic nerve, there were many novel genes with significant expression changes. Among them, neuronatin (Nnat) was the one which expression was significantly up-regulated. Nnat was identified as a gene selectively expressed in neonatal brains and markedly reduced in adult brains. The present study investigated whether the expression of Nnat correlates with symptoms of neuropathic pain in adult rats with transected sciatic nerve.</p> <p>Methods</p> <p>Western blotting, immunohistochemistry, and the Randall and Selitto test were used to study the protein content, and subcellular localization of Nnat in correlation with pain-related animal behavior.</p> <p>Results</p> <p>It was found that after nerve injury, the expression of Nnat was increased in total protein extracts. Unmyelinated C-fiber and thinly myelinated A-δ fiber in adult dorsal root ganglions (DRGs) were the principal sub-population of primary afferent neurons with distributed Nnat. The increased expression of Nnat and its subcellular localization were related to mechanical hyperalgesia.</p> <p>Conclusions</p> <p>The results indicated that there was significant correlation between mechanical hyperalgesia in axotomy of sciatic nerve and the increased expression of Nnat in C-fiber and A-δ fiber of adult DRG neurons.</p

    Mobile robotics platform for strawberry temporal–spatial yield monitoring within precision indoor farming systems

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    Plant phenotyping and production management are emerging fields to facilitate Genetics, Environment, &amp; Management (GEM) research and provide production guidance. Precision indoor farming systems (PIFS), vertical farms with artificial light (aka plant factories) in particular, have long been suitable production scenes due to the advantages of efficient land utilization and year-round cultivation. In this study, a mobile robotics platform (MRP) within a commercial plant factory has been developed to dynamically understand plant growth and provide data support for growth model construction and production management by periodical monitoring of individual strawberry plants and fruit. Yield monitoring, where yield = the total number of ripe strawberry fruit detected, is a critical task to provide information on plant phenotyping. The MRP consists of an autonomous mobile robot (AMR) and a multilayer perception robot (MPR), i.e., MRP = the MPR installed on top of the AMR. The AMR is capable of traveling along the aisles between plant growing rows. The MPR consists of a data acquisition module that can be raised to the height of any plant growing tier of each row by a lifting module. Adding AprilTag observations (captured by a monocular camera) into the inertial navigation system to form an ATI navigation system has enhanced the MRP navigation within the repetitive and narrow physical structure of a plant factory to capture and correlate the growth and position information of each individual strawberry plant. The MRP performed robustly at various traveling speeds with a positioning accuracy of 13.0 mm. The temporal–spatial yield monitoring within a whole plant factory can be achieved to guide farmers to harvest strawberries on schedule through the MRP’s periodical inspection. The yield monitoring performance was found to have an error rate of 6.26% when the plants were inspected at a constant MRP traveling speed of 0.2 m/s. The MRP’s functions are expected to be transferable and expandable to other crop production monitoring and cultural tasks
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