Choked accretion onto Kerr-Sen black holes in Einstein-Maxwell-Dilation-Axion gravity

We study the choked accretion process of an ultrarelativistic fluid onto axisymmetric Kerr-Sen black holes in Einstein-Maxwell-Dilation-Axion theory. We calculate the solution describing the velocity potential $\Phi$ of a stationary, irrotational fluid, which satisfies the stiff equation of state and draw the streamlined diagram of the quadrupolar flow solution. We investigate how parameters affect the solution's coefficient and stagnation point. The injection rate, ejection rate, and critical angle are discussed in detail at the end of the article. If the inner and outer event horizons of the black hole are satisfied, then we can find that the ratio of the ejection rate to the setting rate increases with an increase in the dilation parameter.Comment: 25pages,10 figure

Fluid Data Compression and ROI Detection Using Run Length Method

AbstractIt is difficult to carry out visualization of the large-scale time-varying data directly, even with the supercomputers. Data compression and ROI (Region of Interest) detection are often used to improve efficiency of the visualization of numerical data. It is well known that the Run Length encoding is a good technique to compress the data where the same sequence appeared repeatedly, such as an image with little change, or a set of smooth fluid data. Another advantage of Run Length encoding is that it can be applied to every dimension of data separately. Therefore, the Run Length method can be implemented easily as a parallel processing algorithm. We proposed two different Run Length based methods. When using the Run Length method to compress a data set, its size may increase after the compression if the data does not contain many repeated parts. We only apply the compression for the case that the data can be compressed effectively. By checking the compression ratio, we can detect ROI. The effectiveness and efficiency of the proposed methods are demonstrated through comparing with several existing compression methods using different sets of fluid data

Robotic Cane as a Soft SuperLimb for Elderly Sit-to-Stand Assistance

Many researchers have identified robotics as a potential solution to the aging population faced by many developed and developing countries. If so, how should we address the cognitive acceptance and ambient control of elderly assistive robots through design? In this paper, we proposed an explorative design of an ambient SuperLimb (Supernumerary Robotic Limb) system that involves a pneumatically-driven robotic cane for at-home motion assistance, an inflatable vest for compliant human-robot interaction, and a depth sensor for ambient intention detection. The proposed system aims at providing active assistance during the sit-to-stand transition for at-home usage by the elderly at the bedside, in the chair, and on the toilet. We proposed a modified biomechanical model with a linear cane robot for closed-loop control implementation. We validated the design feasibility of the proposed ambient SuperLimb system including the biomechanical model, our result showed the advantages in reducing lower limb efforts and elderly fall risks, yet the detection accuracy using depth sensing and adjustments on the model still require further research in the future. Nevertheless, we summarized empirical guidelines to support the ambient design of elderly-assistive SuperLimb systems for lower limb functional augmentation.Comment: 8 pages, 9 figures, accepted for IEEE RoboSoft 202

Cascade of singularities in the spin dynamics of a perturbed quantum critical Ising chain

When the quantum critical transverse-field Ising chain is perturbed by a longitudinal field, a quantum integrable model emerges in the scaling limit with massive excitations described by the exceptional $E_{8}$ Lie algebra. Using the corresponding analytical form factors of the quantum $E_{8}$ integrable model, we systematically study the spin dynamic structure factor of the perturbed quantum critical Ising chain, where particle channels with total energy up to 5$m_1$ ($m_1$ being the mass of the lightest $E_{8}$ particle) are exhausted. In addition to the significant single-particle contributions to the dynamic spectrum, each two-particle channel with different masses is found to exhibit an edge singularity at the threshold of the total mass and decays with an inverse square root of energy, which is attributed to the singularity of the two-particle density of states at the threshold. The singularity is absent for particles with equal masses due to a cancellation mechanism involving the structure of the form factors. As a consequence, the dynamic structure factor displays a cascade of bumping peaks in the continuum region with clear singular features which can serve as a solid guidance for the material realization of the quantum $E_{8}$ model.Comment: 12 pages, 8 figure

Observation of E8 Particles in an Ising Chain Antiferromagnet

Near the transverse-field induced quantum critical point of the Ising chain, an exotic dynamic spectrum consisting of exactly eight particles was predicted, which is uniquely described by an emergent quantum integrable field theory with the symmetry of the $E_8$ Lie algebra, but rarely explored experimentally. Here we use high-resolution terahertz spectroscopy to resolve quantum spin dynamics of the quasi-one-dimensional Ising antiferromagnet BaCo$_2$V$_2$O$_8$ in an applied transverse field. By comparing to an analytical calculation of the dynamical spin correlations, we identify $E_8$ particles as well as their two-particle excitations.Comment: 6 pages, 3 figures, plus supplementary material

Quantitative proteomics identification of phosphoglycerate mutase 1 as a novel therapeutic target in hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide with poor prognosis due to resistance to conventional chemotherapy and limited efficacy of radiotherapy. There is an urgent need to develop novel biomarkers for early diagnosis, as well as to identify new drug targets for therapeutic interventions. PATIENTS AND METHODS: 54 paired HCC samples and 21 normal liver tissues were obtained from West China Hospital of Sichuan University. Informed consent was obtained from all the patients or their relatives prior to analysis, and the project was approved by the Institutional Ethics Committee of Sichuan University. Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC)-based proteomics was employed to profile the differentially expressed proteins between a HepG2 human hepatoma cell line and an immortal hepatic cell line L02. Validation of PGAM1 expression was performed by semi-quantitative RT-PCR, immunoblot and immunohistochemistry using clinical samples. shRNA expressing plasmids specifically targeting PGAM1 were designed and constructed by GenePharma Corporation (Shanghai, China), and were utilized to silence expression of PGAM1 in vitro and in vivo. Cell proliferation was measured by a combination of colony formation assay and Ki67 staining. Apoptosis was examined by flow cytometry and TUNEL assay. RESULTS: A total of 63 dysregulated proteins were identified, including 51 up-regulated proteins, and 12 down-regulated proteins (over 2-fold, p < 0.01). Phosphoglycerate mutase 1 (PGAM1) was found markedly upregulated. Clinico-pathological analysis indicated that overexpression of PGAM1 was associated with 66.7% HCC, and strongly correlated with poor differentiation and decreased survival rates (p < 0.01). shRNAs-mediated repression of PGAM1 expression resulted in significant inhibition in liver cancer cell growth both in vitro and in vivo. CONCLUSION: Our studies suggested that PGAM1 plays an important role in hepatocarcinogenesis, and should be a potential diagnostic biomarker, as well as an attractive therapeutic target for hepatocellular carcinoma

Assessment of vocational training needs for animal husbandry in Qinghai Province of China

Qinghai is one of the five major pastoral areas and the largest province in China. Although Qinghai has a huge land mass and a small population, it is the poorest province in China. The overarching goal of vocational education in China has been officially defined as serving the socialist economic construction. In this paper, the author studies what kind of animal husbandry vocational training exists and is needed for Qinghai Province. The research methodology was composed of semi-structured interviews with administrators, teachers, students and focus groups of herds people. The respondents were from seven vocational training schools and three prefectures in Qinghai province. The conclusion is that the current livestock vocational training schools do not meet the needs of the herds people because of the lack of schools, rigor of the school entrance examination, and the abounding financial constraints for the herds people. These difficulties prevent the herds people from attaining animal husbandry vocational training