5,297 research outputs found
Spin Structure of the Proton
By assuming that there is no significant intrinsic polarization of the gluon,
we have computed the polarized quark contributions to the proton's spin under
SU(3) flavor symmetry breaking for the polarized sea and have performed a
global leading-order QCD fit to obtain the spin-dependent quark distributions,
which could be used as input for analyzing lepton-hadron and hadron-hadron
collisions.Comment: 13 pages, NCKU-HEP/94-0
Structural Aspects of the Proton in the Chiral Quark Model
We calculate with chiral symmetry the parton contents of the proton based on
a two-component wave function. The calculation results give significant
sea-quark contents and, especially, the intrinsic gluon polarization produced
at a more fundamental level.Comment: 10 pages, LaTe
Probing gravitational non-minimal coupling with dark energy surveys
We investigate observational constraints on a specific one-parameter
extension to the minimal quintessence model, where the quintessence field
acquires a quadratic coupling to the scalar curvature through a coupling
constant . The value of is highly suppressed in typical tracker
models if the late-time cosmic acceleration is driven at some field values near
the Planck scale. We test in a second class of models in which the field
value today becomes a free model parameter. We use the combined data from
type-Ia supernovae, cosmic microwave background, baryon acoustic oscillations
and matter power spectrum, to weak lensing measurements and find a best-fit
value where is excluded outside the 95 per cent
confidence region. The effective gravitational constant subject
to the hint of a non-zero is constrained to at the same confidence level on cosmological scales, and can be narrowed
down to when combining with Solar
System tests.Comment: Context extended, figures and references added, title changed to
match with accepted version for publicatio
"Teleparallel" Dark Energy
Using the "teleparallel" equivalent of General Relativity as the
gravitational sector, which is based on torsion instead of curvature, we add a
canonical scalar field, allowing for a nonminimal coupling with gravity.
Although the minimal case is completely equivalent to standard quintessence,
the nonminimal scenario has a richer structure, exhibiting quintessence-like or
phantom-like behavior, or experiencing the phantom-divide crossing. The richer
structure is manifested in the absence of a conformal transformation to an
equivalent minimally-coupled model.Comment: 5 pages, 1 figure, Version published in PLB704 (2011) 384-38
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Liquid biopsy genotyping in lung cancer: ready for clinical utility?
Liquid biopsy is a blood test that detects evidence of cancer cells or tumor DNA in the circulation. Despite complicated collection methods and the requirement for technique-dependent platforms, it has generated substantial interest due, in part, to its potential to detect driver oncogenes such as epidermal growth factor receptor (EGFR) mutants in lung cancer. This technology is advancing rapidly and is being incorporated into numerous EGFR tyrosine kinase inhibitor (EGFR-TKI) development programs. It appears ready for integration into clinical care. Recent studies have demonstrated that biological fluids such as saliva and urine can also be used for detecting EGFR mutant DNA through application other user-friendly techniques. This review focuses on the clinical application of liquid biopsies to lung cancer genotyping, including EGFR and other targets of genotype-directed therapy and compares multiple platforms used for liquid biopsy
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