Interviews with Wilson G. Shelley, Paul Sissel, Lark Lyn Gunther, Ida L. Phillips, May Swanson and Frank Gull

Interviews with Wilson G. Shelley, Paul Sissel, Lark Lyn Gunther, Ida L. Phillips, May Swanson and Frank Gull. This recording is unavailable.https://scholars.fhsu.edu/sackett/1101/thumbnail.jp

Interview with Lawrence Weigel, Kilian Leiker, Lark Lowell Gunther, Ida L. Steward, and Wesson G. Shelly

Interviews with Lawrence Weigel, Kilian Leiker, Lark Lowell Gunther, Ida L. Steward, and Wesson G. Shelly. This recording is unavailable.https://scholars.fhsu.edu/sackett/1099/thumbnail.jp

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

non present