232 research outputs found

    AKI patients have worse long-term outcomes, especially in the immediate post-ICU period

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    Acute kidney injury (AKI) is associated with worse outcome in the acute phase of acute illness but also in the chronic phase. In a large Danish study in this issue of Critical Care, 1-year mortality was higher in patients with AKI than in patients without AKI. Mortality was most important during the first 50 days after admission to the intensive c are unit (ICU), whereas after 2 months the survival curves of patients with AKI and those of patients without AKI were similar. The reasons for this observation are not clear, but protracted critical illness and fragility after acute critical illness probably play important roles. Because we see more and more of these patients, they should be the focus of ICU research. Consequently, ICU and post-ICU care for these patients requires focus and a more integrated approach to the specific problems of these survivors of acute critical illness

    Epidemiology and outcome in intensive care patients with acute kidney injury treated with renal replacement therapy

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    Fatigue crack behaviour : comparing three-point bend test and wedge splitting test data on vibrated concrete using Paris' law

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    The fatigue behaviour of concrete has become more important for the design of constructions due to the desire to build slimmer structures, which are more sensitive to fatigue loading. This article aims to evaluate and compare the fatigue crack propagation rate in vibrated concrete for four different stress ratios using the Paris-Erdogan law. The data evaluation in this article is based on crack mouth opening displacement (CMOD) measurements from cyclic three-point bending tests on single edge notched beams and from wedge splitting tests on notched cubes, obtained from experiments at Ghent University. For this study, finite element analysis is used to obtain a mathematical relationship between the CMOD and the relative crack length a/W, as well as a relationship between the stress intensity ratio ∆K and a/W. The obtained mathematical relationships were then combined with the measured CMOD values to correlate the test data to the Paris-Erdogan law. Herein, the crack propagation rate da/dN is plotted against the corresponding stress intensity range ∆K in a log-log graph. In a final step, the Paris-Erdogan law parameters C and m were obtained through linear curve fitting on the data points from the obtained graphs. The parameters C and m are then used to compare and evaluate the fatigue crack behavior in vibrated concrete, and the differences between the results from the three-point bend tests and wedge splitting tests

    The structural behavior of tiled laminate GFRP composites, a class of robust materials for civil applications

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    This paper focuses on the structural behavior of tiled laminate composites. Such laminates, in which the plies are not parallel to the outer surfaces are found in GFRP bridge deck panels. The technology is developed for the construction of robust GFRP panels useful in highly loaded structures such as bridges or lock gates. In civil structures, the drawback in traditional FRP sandwich structures has always been debonding of skin and core. Such a debonding problem may occur after unintentional impact, followed by fatigue loading. Through the concept of using overlapping Z-shaped and two-flanged web laminates, alternating with polyurethane foam cores, debonding is no longer possible in vacuum infused GFRP bridge deck panels. In such panels, the fibers in the upper and lower skins as well as in the vertical webs run in all directions, rendering a resin-dominated crack propagation impossible. As a result of the integration of core and skin reinforcement, a skin material is created in which the reinforcement is not parallel to the outer surfaces, but tiled. Based on experimental results and numerical simulations the relevance of tiled laminates for civil applications is demonstrated

    Vibrated concrete vs. self-compacting concrete: comparison of fracture mechanics properties

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    This study focuses on the fracture mechanics aspect of self-compacting concrete, compared to vibrated concrete. The most commonly used experiments to investigate the toughness and cracking behaviour of concrete are the three-point bending test (3PBT) on small, notched beams, and the wedge-splitting test (WST) on cubic samples with guiding groove and starter notch. From the resulting P-CMOD curves (applied load versus crack mouth opening displacement), different fracture parameters, such as fracture energy and fracture toughness, can be extracted. Moreover, using inverse analysis, the sigma-w relationship (tensile stress versus crack width) can be derived. This paper lists the results of a series of tests on samples, made of VC, SCC of equal strength, and SCC with identical w/c factor. Subsequently, a comparison of the mechanical characteristics is made, revealing important differences regarding several fracture parameters

    Experimental investigation of concrete fatigue resistance

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    A lack of knowledge on the fatigue resistance of self-compacting concrete (SCC) structures has led to the research presented in this paper. Several reinforced concrete beams were subjected to both static and cyclic four-point bending tests in order to determine the failure mechanism, the static ultimate load, the fatigue performance, the deformation, and crack width evolution. For comparison purpose, different mixtures were considered, including a vibrated concrete (VC) type and two SCCs (one with similar strength and one with equal w/c ratio, compared to VC). The mutual relationship is strongly depending on the stress level caused by the repeated loading

    Comparative study on the fatigue behaviour of SCC and VC

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    Continuous cyclic loading on concrete constructions involves a progressive cracking mechanism, leading to significant changes of the material properties during the lifetime of the structure. Gradually, irreversible damage is inflicted and the carrying capacity is affected, which may cause structural collapse at a stress or strain level much lower than in case of a single static load. This so-called fatigue phenomenon is well-documented in literature for traditional, vibrated concrete (VC), but this is not the case for self-compacting concrete (SCC). Given the fact that this latter concrete type is already used worldwide in many types of structures, including cyclically loaded ones, a good knowledge and understanding of the static and fatigue material behaviour is crucial. Up till now, it is unsure whether SCC performs better, worse, or equally under fatigue loading conditions. Therefore, in this study, destructive four-point bending tests are performed on large beams, made from VC and SCC, both statically and cyclically (at different loading rates). A comparison of the deflection, strain, crack pattern and crack width evolution of the different concrete types is made. The results reveal some significant differences regarding concrete strain and crack width development during the cyclic tests

    Structural and thermal performances of topological optimized masonry blocks

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    Structural topology optimization is the most fundamental form of structural optimization and receives an increasing attention from engineers and structural designers. The method enables the exploration of the general topology and shape of structural elements at an early stage of the design process and gives rise to inspiring and innovative improvements. In this paper, topology optimization as a principle is used to design new types of insulating masonry blocks. Two main objectives are addressed: maximizing the structural stiffness and minimizing the thermal transmittance. The first part of this paper uses these objectives to create new block topologies. A general problem is formulated and the influences of boundary conditions, external loading, and filter value on the resulting geometry are discussed. In general, maximizing the stiffness is in strong contrast to minimizing the thermal transmittance. This causes problems not encountered in conventional topology optimization. Nevertheless, by adjusting the interpolation schemes and adding multiple load groups, convergent solutions are found. An isotropic material model with an enforced solid-or-empty distribution is considered as the primary method. The optimized block topologies are then thoroughly analyzed to review their structural and thermal performance using the commercial finite element software Abaqus. The direct compressive strength of the block is a measure of the structural performance and the equivalent thermal conductivity gives an indication of the thermal performance. The second part then gives some thoughts on three-dimensional optimization and the incorporation of mesostructures in the design

    Non-linear 3D finite element analysis of the anchorage zones of pretensioned concrete girders and experimental verification

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    This paper focuses on the modelling of the anchorage zone of a pretensioned girder. The finite element software Abaqus was used to create a 3D non-linear finite element model (FEM). This analysis was performed on a full-scale pretensioned girder with end blocks and with various types of strand modelling, where accurate contact properties between prestressing steel and concrete are essential. The model has been validated by comparing the numerical strain results with the strain measurements on a full-scale girder with end blocks, which was produced in a precast concrete plant. At the same time, a parametric study was executed to determine the value of the coefficient of friction between the strands and the concrete and to examine the sensitivity of the input parameters of the model. The results have indicated that an accurate determination of the concrete properties at the time of release is very important. Furthermore, the Hoyer effect is analysed. It is found that the radial expansion of the strand in the finite element model is in good agreement with the theoretically calculated expansion of the strand which demonstrates the accuracy of the finite element model. In addition, it is shown that the Hoyer effect influences the force transfer of two adjacent strands. The aim of this research is to investigate the potential of an alternative FE model of a pretensioned girder based on strand to concrete frictional behaviour, rather than the commonly used models based on an assumed shear stress distribution along the transfer length

    Numerical and experimental analysis of the transfer length and its influence on the anchorage zone design of pretensioned concrete members

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    In order to optimize the end block of a prestressed girder, nonlinear finite element models are frequently used. This way the stresses and possible cracks in the anchorage zones can be predicted in a more reliable manner. However, a preliminary parametric study of nonlinear finite element models has shown that the transfer length has a major influence on the stresses in the concrete and in the reinforcement, and on the crack formation. In this paper this transfer length is examined, firstly by performing a parametric study of the formulations found in literature, secondly by measurements on beams produced at a precast concrete plant. The aim of this parametric study and the experimental research is to get further insight into the transfer length function as required for further numerical analysis of the end zones
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