Single-energy amplitudes for pion photoproduction in the first resonance region

We consider multipole amplitudes for low-energy pion photoproduction, constructed with minimal model dependence, at single energies. Comparisons with fits to the full resonance region are made. Explanations are suggested for the discrepancies and further experiments are motivated.Comment: 12 pages, 5 figure

Amplitude ambiguities in pseudoscalar meson photoproduction

We consider the problem of determining amplitudes from observables for the case of pseudoscalar meson photoproduction. We find a number of surprisingly simple constraints which give necessary conditions for a complete set of measurements. These results contradict one of the selection rules derived previously.Comment: 7 page

In vitro antitumour activity of the novel imidazoisoquinoline SDZ 62-434.

The novel imidazoisoquinoline SDZ 62-434, originally identified as a platelet-activating factor (PAF) antagonist, has antiproliferative activity in a range of cell lines from human solid and haematological malignancies. Using an MTT cytotoxicity assay, IC50 values of 5 microM - 111 microM were observed following a 24 h exposure. Similar results were obtained using a clonogenic assay. The HT29 colon adenocarcinoma was particularly sensitive while the MCF-7 breast carcinoma was the most resistant in our panel. Only a 2-3 fold cross-resistance was seen in the doxorubicin and cisplatin resistant variants of the A2780 ovarian carcinoma; the drug did not modulate sensitivity to doxorubicin in either parent or resistant lines. No cross-resistance to SDZ 62-434 was seen in a doxorubicin-resistant MCF-7 variant. Cytotoxicity was not due to non-specific membrane lysis. The potent PAF antagonist WEB 2086 did not modulate SDZ 62-434 cytotoxicity, indicating no role for PAF receptors. Precursor incorporation studies in A2780 cells showed that DNA synthesis was inhibited more effectively than protein synthesis while RNA synthesis was unaffected. SDZ 62-434 inhibited both bombesin and platelet-derived growth factor-induced DNA synthesis in quiescent Swiss 3T3 cells. This suggests a possible role for SDZ 62-434 as an inhibitor of signal transduction in cancer cells

Determining the prevalence of malnutritionin hospitalised paediatric patients

Aim. To determine the prevalence of malnutrition in hospitalised paediatric patients at Red Cross War Memorial Children’s Hospital. Method. A 1-day cross-sectional survey was completed in all medical and surgical wards and some specialist outpatient clinics. Results. A total of 227 children participated in the study. Thirty-five per cent of patients were moderately malnourished (b -2 z-score), of whom 70% had no road to health card with them. Thirty-four per cent of children under 60 months of age received supplements in addition to a normal ward diet, 7.8% were enterally fed and less than 1% were parenterally fed. Almost 14% of children were found to be overweight/ obese, which is higher than the national average of 6%. The prevalence of HIV infection on the day of the audit was 18% across all age groups compared with the Western Cape antenatal prevalence of 15.7% (2005). Conclusion. The overall prevalence of undernutrition was 34%, which is comparable with similar studies. However, the proportion of overweight children (14%) was greater than the national average. In view of the level of malnutrition seen, a nutrition risk-screening tool, identifying risk factors for malnutrition such as food access and vulnerability, should be developed. The tool should be used to assess nutrition status and risk during the course of hospitalisation, in addition to planning appropriate nutrition care plan interventions for discharge

Evaluation of the gn-->pi-p differential cross sections in the Delta-isobar region

Differential cross sections for the process gn-->pi-p have been extracted from MAMI-B measurements of gd-->pi-pp, accounting for final-state interaction effects, using a diagrammatic technique taking into account the NN and piN final-state interaction amplitudes. Results are compared to previous measurements of the inverse process, pi-p--> ng, and recent multipole analyses.Comment: 6 pages, 4 figures. v2: Further clarifications and minor changes. A new figure inserte

Updated analysis of NN elastic scattering to 3 GeV

A partial-wave analysis of NN elastic scattering data has been updated to include a number of recent measurements. Experiments carried out at the Cooler Synchrotron (COSY) by the EDDA Collaboration have had a significant impact above 1 GeV. Results are discussed in terms of the partial-wave and direct-reconstruction amplitudes.Comment: 16 pages, 14 figures, 2 tables; Fig 10 error corrected; Accepted for publication in Physical Review

Different esterase activities of exponential and plateau phases of EMT6 cells monitored by flow cytofluorimetry.

The reaction rates of enzymes hydrolysing fluorescein diacetate have been studied in populations of intact tissue-culture EMT6, cells using flow cytofluorimetric techniques. It was found that the activity of these enzymes increased in plateau phases and that this correlated inversely with plating efficiency. Highly abnormal substrate-dependent reaction velocity kinetics were found in 14-, 21-, 28- and 35-day cultures

Helicity-dependent photoabsorption cross sections on the nucleon

We examine the energy dependence of single-meson photoproduction as it contributes to the Gerasimov-Drell-Hearn (GDH) sum rule. For photon energies above approximately 1 GeV, through the full resonance region, this contribution dominates the proton sum rule integral. Over the same energy region, our single-pion contribution to the neutron sum rule also qualitatively follows a recent set of GDH data. The predicted neutral-pion contribution to the neutron sum rule is nearly zero above 1 GeV in this result. The SAID and Mainz (MAID) results are very different for a number of observables over this energy region.Comment: 7 pages, 5 figur

Present status of the nonstrange and other flavor partners of the exotic Theta+ baryon

Given the existing empirical information about the exotic Theta+ baryon, we analyze possible properties of its SU(3)F-partners, paying special attention to the nonstrange member of the antidecuplet N*. The modified piN partial-wave analysis presents two candidate masses, 1680 MeV and 1730 MeV. In both cases, the N* should be rather narrow and highly inelastic. Our results suggest several directions for experimental studies that may clarify properties of the antidecuplet baryons, and structure of their mixing with other baryons. Recent experimental evidence from the GRAAL and STAR Collaborations could be interpreted as observations of a candidate for the Theta+ nonstrange partner.Comment: 4 pages, 1 figure, talk given at the Topical Group on Hadron Physics (Fermilab, Oct. 24-26, 2004

Prevalence of bacterial contamination of powdered infant feeds in a hospital enviroment

Background. The study arose as part of a best-practice nutrition model regarding the introduction of ready-to-use (RTU) infant feeds in place of powdered infant feeds (PIFs) as a standard formula for infants under the age of 1 year who are unable to be breastfed. Internationally and locally there is grave concern regarding the safety and efficacy of mixing PIFs, especially in a hospital setting, and the resultant bacterial contamination causing enteric infections, especially in premature, immunocompromised and sick infants. Objective. To evaluate the prevalence of bacterial contamination of PIFs given to infants at Red Cross War Memorial Children’s Hospital, Cape Town. Methods. Quantitative levels of bacterial contamination were determined and were expressed as colony-forming units (CFUs) per millilitre of sample. Aliquots of milk were inoculated onto agar, and the milk samples were then incubated at 25o C overnight (N = 10), 30o C overnight (N = 48) and 30o C for 6 hours (N = 34). Post-incubation milk samples were cultured again. Contamination was defined as any positive culture before administration (i.e. pre incubation) or > 102 CFU/ ml after administration (i.e. post incubation). Results. Fifty samples of PIFs (N = 82) were contaminated pre incubation, with 25/82 samples (30.4%) being heavily contaminated (≥ 104 CFU/ml). Post incubation, 43/92 samples (46.7%) were contaminated with > 102 CFU/ml. The acidified PIFs appeared to have some bactericidal effect against some of the organisms, but not all. Conclusions. RTU infant feeds are sterile and are recommended for use in all hospitalised infants. The results of this study indicate that even when milk is prepared in a controlled environment there is significant bacterial contamination of PIFs post production. As RTU feeds are now readily available in South Africa every attempt should be made to use a sterile RTU system for hospitalised infant