479 research outputs found
Protecting Retired Workers from Inflation: Collective Bargaining for Retiree Benefits
The purpose of this article is to explore whether the collective bargaining process in its present form, or with certain modifications, can provide workers with meaningful protection against inflation. Part I evaluates the adequacy of the collective bargaining process by examining the internal dynamics of unions, the interests of employers and the application of the doctrine of fair representation to collective bargaining. After concluding that the current system inadequately protects retirees, Part II proposes alternative methods to strengthen the role of retirees in the collective bargaining process
DESCRIPTION OF THE LARVAE OF TWO SPECIES OF \u3ci\u3eHEMIPEPLUS LATREILLE\u3c/i\u3e (COLEOPTERA:MYCTERIDAE)
The key description and illustrations of mouthparts, ocelli, and terminal abdominal segments by Bovinq & Craighead (1931) have been the only information on the larval stages of the genus Hemipeplus Latreille, except for the observation by van Emden (1942) that individuals of the genus would not key properly in Boving & Craighead\u27s key. Their example was of an undescribed species from Cuba. The semidiagrammatic illustrations make it difficult to identify the species illustrated, although it may be H. marginipennis (LeConte). This paper is based on larvae collected by the authors, in each case associated with adults. From the family diagnosis of larval Mycteridae (Crowson & Viedma 1964). Hemipeplus larvae differ noticeably in the form of the sensorium, which Crowson & Viedma describe as âvery short, dome-shapedâ; in Hemipeplus it is elongate and conical. From the larva of Mycterus (described by Crowson & Viedma 1964) those of Hemipeplus also differ in having five ocelli on each side (cf. two), mala with an uncus and medial pit (cf. without uncus or medial pit), mola ridged (cf. not ridged), cardines not divided (cf. distinctly divided, labial palpi with only one distinct palpomere (cf. with two palpomeres), abdominal asperities absent (cf. asperities present), and different form of spiracle (compare fig. 13 with fig. 4 in Crowson & Viedma 1964). Larvae of Hemipeplus are more similar to that of Eurypus muelleri Seldlitz (described by Costa & Vanin 1977) than to that of Mycterus. As in Hemipeplus, Eurypus larvae possess five ocelli arranged in rows of three and two on each side; two pairs of tubercles at posterior margin of abdominal sternite IX; mala with an uncus, and cardines divided. Hemipeplus larvae differ from those of Mycterus most notably in the form of abdominal tergite IX (see Costa & Vanin 1977:fig. 2 ) . The uncus is located on the mesal margin of the mala in Hemipeplus, whereas it is located on the ventral aspect of the mala in Eurypus
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Leveraging Epidemiology to Improve Risk Assessment.
The field of environmental public health is at an important crossroad. Our current biomonitoring efforts document widespread exposure to a host of chemicals for which toxicity information is lacking. At the same time, advances in the fields of genomics, proteomics, metabolomics, genetics and epigenetics are yielding volumes of data at a rapid pace. Our ability to detect chemicals in biological and environmental media has far outpaced our ability to interpret their health relevance, and as a result, the environmental risk paradigm, in its current state, is antiquated and ill-equipped to make the best use of these new data. In light of new scientific developments and the pressing need to characterize the public health burdens of chemicals, it is imperative to reinvigorate the use of environmental epidemiology in chemical risk assessment. Two case studies of chemical assessments from the Environmental Protection Agency Integrated Risk Information System database are presented to illustrate opportunities where epidemiologic data could have been used in place of experimental animal data in dose-response assessment, or where different approaches, techniques, or studies could have been employed to better utilize existing epidemiologic evidence. Based on the case studies and what can be learned from recent scientific advances and improved approaches to utilizing human data for dose-response estimation, recommendations are provided for the disciplines of epidemiology and risk assessment for enhancing the role of epidemiologic data in hazard identification and dose-response assessment
Description of the larvae of two species of Hemipeplus Latreille (Coleoptera: Mycteridae)
The key description and illustrations of mouthparts, ocelli, and terminal abdominal segments by Bovinq & Craighead (1931) have been the only information on the larval stages of the genus Hemipeplus Latreille, except for the observation by van Emden (1942) that individuals of the genus would not key properly in Boving & Craighead's key. Their example was of an undescribed species from Cuba. The semidiagrammatic illustrations make it difficult to identify the species illustrated, although it may be H. marginipennis (LeConte). This paper is based on larvae collected by the authors, in each case associated with adults. From the family diagnosis of larval Mycteridae (Crowson & Viedma 1964). Hemipeplus larvae differ noticeably in the form of the sensorium, which Crowson & Viedma describe as âvery short, dome-shapedâ; in Hemipeplus it is elongate and conical. From the larva of Mycterus (described by Crowson & Viedma 1964) those of Hemipeplus also differ in having five ocelli on each side (cf. two), mala with an uncus and medial pit (cf. without uncus or medial pit), mola ridged (cf. not ridged), cardines not divided (cf. distinctly divided, labial palpi with only one distinct palpomere (cf. with two palpomeres), abdominal asperities absent (cf. asperities present), and different form of spiracle (compare fig. 13 with fig. 4 in Crowson & Viedma 1964). Larvae of Hemipeplus are more similar to that of Eurypus muelleri Seldlitz (described by Costa & Vanin 1977) than to that of Mycterus. As in Hemipeplus, Eurypus larvae possess five ocelli arranged in rows of three and two on each side; two pairs of tubercles at posterior margin of abdominal sternite IX; mala with an uncus, and cardines divided. Hemipeplus larvae differ from those of Mycterus most notably in the form of abdominal tergite IX (see Costa & Vanin 1977:fig. 2 ) . The uncus is located on the mesal margin of the mala in Hemipeplus, whereas it is located on the ventral aspect of the mala in Eurypus
Extended Reconstructed Sea Surface Temperature Version 4 (ERSST.v4): Part II. Parametric and Structural Uncertainty Estimations
Described herein is the parametric and structural uncertainty quantification for the monthly Extended
Reconstructed Sea Surface Temperature (ERSST) version 4 (v4). A Monte Carlo ensemble approach was
adopted to characterize parametric uncertainty, because initial experiments indicate the existence of significant
nonlinear interactions. Globally, the resulting ensemble exhibits a wider uncertainty range before 1900, as well
as an uncertainty maximum around World War II. Changes at smaller spatial scales in many regions, or for
important features such as Niño-3.4 variability, are found to be dominated by particular parameter choices.
Substantial differences in parametric uncertainty estimates are found between ERSST.v4 and the
independently derived Hadley Centre SST version 3 (HadSST3) product. The largest uncertainties are over
the mid and high latitudes in ERSST.v4 but in the tropics in HadSST3. Overall, in comparison with HadSST3,
ERSST.v4 has larger parametric uncertainties at smaller spatial and shorter time scales and smaller parametric
uncertainties at longer time scales, which likely reflects the different sources of uncertainty quantified
in the respective parametric analyses. ERSST.v4 exhibits a stronger globally averaged warming trend than
HadSST3 during the period of 1910â2012, but with a smaller parametric uncertainty. These global-mean trend
estimates and their uncertainties marginally overlap.
Several additional SST datasets are used to infer the structural uncertainty inherent in SST estimates. For the
global mean, the structural uncertainty, estimated as the spread between available SST products, is more often
than not larger than the parametric uncertainty in ERSST.v4. Neither parametric nor structural uncertainties
call into question that on the global-mean level and centennial time scale, SSTs have warmed notably
Effect of ventricular function on the exercise hemodynamics of variable rate pacing
AbstractTo determine the effect of ventricular function on the exercise hemodynamics of variable rate pacing, 16 selected patients underwent paired, double-blind, randomized exercise tests in single rate demand (VVI) or variable rate (VVIR) pacing modes. Ejection fraction and cardiac index were determined by two-dimensional and Doppler echocardiography at baseline and during peak exercise.Baseline ejection fraction ranged from 14 to 73% and was < 40% in 6 patients (Group 1) and â„ 40% in 10 patients (Group 2). Duration of exercise was longer during the VVIR mode (502 s) than during the VVI mode (449 s) (p < 0.01) and unrelated to baseline ejection fraction. Heart rate during exercise increased 9% in the VVI mode and 35% in the VVIR mode (p < 0.005). Cardiac index increased 49% in the VVI mode and 83% in the VVIR mode. Analysis of variance for repeated measures showed a significant effect of pacing mode (p < 0.01) and exercise (p < 0.001), but not baseline ejection fraction, on cardiac index. Baseline ejection fraction did not correlate with the increase in cardiac index in either pacing mode or with the difference in increase between modes. There was no significant difference between Groups 1 and 2 in exercise duration, peak heart rate-blood pressure (rate-pressure) product, baseline or peak heart rate or baseline or peak cardiac index.Therefore, in selected patients, VVIR pacing during exercise results in an increase in heart rate, duration of exercise and cardiac index that is unrelated to the degree of baseline left ventricular dysfunction. These data have clinical implications for the use of variable rate pacemakers in patients with abnormalities of ventricular function
Probable Transmission of Coxsackie B3 Virus from Human to Chimpanzee, Denmark
In 2010, a chimpanzee died at Copenhagen Zoo following an outbreak of respiratory disease among chimpanzees in the zoo. Identification of coxsackie B3 virus, a common human pathogen, as the causative agent, and its severe manifestation, raise questions about pathogenicity and transmissibility among humans and other primates
Effect of preoperative thoracic duct drainage on canine kidney transplantation
Chronic drainage of the thoracic duct to the esophagus was developed in dogs, and its efficacy in immunomodulation was tested using kidney transplantation. Compared to 9.7 days in the control, the mean animal survival was prolonged to 9.9 days, 17.8 days, and 18.5 days when TDD was applied preoperatively for 3 weeks, 6 weeks, and 9 weeks, respectively. Prolongation was significant after 6 weeks. Patency of the fistula was 93.5, 80.4, and 76.1% at respective weeks. Number of peripheral T-lymphocytes determined by a new monoclonal antibody diminished after 3 weeks. All animals were in normal health, requiring no special care for fluid, electrolyte, or protein replacement
Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus.
Idiopathic congenital nystagmus is characterized by involuntary, periodic, predominantly horizontal oscillations of both eyes. We identified 22 mutations in FRMD7 in 26 families with X-linked idiopathic congenital nystagmus. Screening of 42 singleton cases of idiopathic congenital nystagmus (28 male, 14 females) yielded three mutations (7%). We found restricted expression of FRMD7 in human embryonic brain and developing neural retina, suggesting a specific role in the control of eye movement and gaze stability
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