The Sampling Strategy for Countryside Survey (up to 2007). Revised and Updated from: ‘The Sampling Strategy for Countryside Survey’, C.J. Barr, September 1998. DETR CONTRACT No. CR0212

The sampling strategy used for the field survey element of Countryside Survey 2007 is the latest in a series of developments of the ITE Land Classification, first used to stratify a field sample in 1978. To understand exactly how the present Countryside Survey sampling framework has been derived, it is important to review the concepts and activities that have evolved over the last 30 years since the first survey was carried out. It is possible that if the earlier time-series data were not so valuable as a basis for detecting change, and a fresh start could be made today, then a different sampling strategy might be well be adopted. However, the present Countryside Survey methodology is inextricably linked with its predecessors and an understanding of these is essential

Parity Violation in Astrophysics

Core collapse supernovae are gigantic explosions of massive stars that radiate 99% of their energy in neutrinos. This provides a unique opportunity for large scale parity or charge conjugation violation. Parity violation in a strong magnetic field could lead to an asymmetry in the neutrino radiation and recoil of the newly formed neutron star. Charge conjugation violation in the neutrino-nucleon interaction reduces the ratio of neutrons to protons in the neutrino driven wind above the neutron star. This is a problem for r-process nucleosynthesis in this wind. On earth, parity violation is an excellent probe of neutrons because the weak charge of a neutron is much larger than that of a proton. The Parity Radius Experiment (PREX) at Jefferson Laboratory aims to precisely measure the neutron radius of $^{208}$Pb with parity violating elastic electron scattering. This has many implications for astrophysics, including the structure of neutron stars, and for atomic parity nonconservation experiments.}Comment: 4 pages, 2 figures, proceedings of PAVI04 conference in Grenoble, Franc

Experimental determination of the 6s^2 ^1S_0 -> 5d6s ^3 D_1 magnetic-dipole transition amplitude in atomic ytterbium

We report on a measurement of the highly forbidden 6s^2 ^1S_0 \to 5d6s ^3 D_1 magnetic-dipole transition in atomic ytterbium using the Stark-interference technique. This amplitude is important in interpreting a future parity nonconservation experiment that exploits the same transition. We find $| | ~ = ~ 1.33(6)_{Stat}(20)_{\beta} \times 10^{-4} \mu_0$, where the larger uncertainty comes from the previously measured vector transition polarizability $\beta$. The $M1$ amplitude is small and should not limit the precision of the parity nonconservation experiment.Comment: 4 pages, 5 figures Paper resubmitted with minor corrections and additions based on comments from referee

Accuracy and Limitations of Fitting and Stereoscopic Methods to Determine the Direction of Coronal Mass Ejections from Heliospheric Imagers Observations

Using data from the Heliospheric Imagers (HIs) onboard STEREO, it is possible to derive the direction of propagation of coronal mass ejections (CMEs) in addition to their speed with a variety of methods. For CMEs observed by both STEREO spacecraft, it is possible to derive their direction using simultaneous observations from the twin spacecraft and also, using observations from only one spacecraft with fitting methods. This makes it possible to test and compare different analyses techniques. In this article, we propose a new fitting method based on observations from one spacecraft, which we compare to the commonly used fitting method of Sheeley et al. (1999). We also compare the results from these two fitting methods with those from two stereoscopic methods, focusing on 12 CMEs observed simultaneously by the two STEREO spacecraft in 2008 and 2009. We find evidence that the fitting method of Sheeley et al. (1999) can result in significant errors in the determination of the CME direction when the CME propagates outside of 60deg \pm 20 deg from the Sun-spacecraft line. We expect our new fitting method to be better adapted to the analysis of halo or limb CMEs with respect to the observing spacecraft. We also find some evidence that direct triangulation in the HI fields-of-view should only be applied to CMEs propagating approximatively towards Earth (\pm 20deg from the Sun-Earth line). Last, we address one of the possible sources of errors of fitting methods: the assumption of radial propagation. Using stereoscopic methods, we find that at least seven of the 12 studied CMEs had an heliospheric deflection of less than 20deg as they propagated in the HI fields-of-view, which, we believe, validates this approximation.Comment: 17 pages, 6 figures, 2 tables, accepted to Solar Physic

A longitudinal study of the biometric and refractive changes in full-term infants during the first year of life

AbstractChanges in ocular axial dimensions and refraction were followed longitudinally, using ultrasonography and retinoscopy, during the first year of life (mean ages 4–53 weeks) of a group of 20 full-term infants (10 male, 10 female). Using a mixed-model regression analysis, axial length changes as a function of time were found to be best described by a quadratic expression (AL=17.190+0.128x−0.0013x2, where AL is the axial length in mm and x is the age in weeks), while anterior chamber depth changed linearly (ACD=2.619+0.018x, where ACD is the anterior chamber depth in mm): lens thickness was essentially constant. Spherical equivalent refraction through most of the first year showed a steady reduction in hypermetropia (SER=2.982−0.032x, where SER is the spherical equivalent refraction in dioptres): astigmatism also tended to diminish. Mean hyperopic refractive errors through the year were negatively correlated with corresponding axial lengths (SER=12.583−0.541AL), but some individual subjects showed marked departures from this pattern. These results are discussed in relation to concepts of emmetropization

Evaluation of two lyophilized molecular assays to rapidly detect foot-and-mouth disease virus directly from clinical samples in field settings

Accurate, timely diagnosis is essential for the control, monitoring and eradication of foot‐and‐mouth disease (FMD). Clinical samples from suspect cases are normally tested at reference laboratories. However, transport of samples to these centralized facilities can be a lengthy process that can impose delays on critical decision making. These concerns have motivated work to evaluate simple‐to‐use technologies, including molecular‐based diagnostic platforms, that can be deployed closer to suspect cases of FMD. In this context, FMD virus (FMDV)‐specific reverse transcription loop‐mediated isothermal amplification (RT‐LAMP) and real‐time RT‐PCR (rRT‐PCR) assays, compatible with simple sample preparation methods and in situ visualization, have been developed which share equivalent analytical sensitivity with laboratory‐based rRT‐PCR. However, the lack of robust ‘ready‐to‐use kits’ that utilize stabilized reagents limits the deployment of these tests into field settings. To address this gap, this study describes the performance of lyophilized rRT‐PCR and RT‐LAMP assays to detect FMDV. Both of these assays are compatible with the use of fluorescence to monitor amplification in real‐time, and for the RT‐LAMP assays end point detection could also be achieved using molecular lateral flow devices. Lyophilization of reagents did not adversely affect the performance of the assays. Importantly, when these assays were deployed into challenging laboratory and field settings within East Africa they proved to be reliable in their ability to detect FMDV in a range of clinical samples from acutely infected as well as convalescent cattle. These data support the use of highly sensitive molecular assays into field settings for simple and rapid detection of FMDV

A convenient chemoenzymatic preparation of chimeric macrocyclic peptide antibiotics with potent activity against gram-negative pathogens

Microbial Biotechnolog

Speeds and arrival times of solar transients approximated by self-similar expanding circular fronts

The NASA STEREO mission opened up the possibility to forecast the arrival times, speeds and directions of solar transients from outside the Sun-Earth line. In particular, we are interested in predicting potentially geo-effective Interplanetary Coronal Mass Ejections (ICMEs) from observations of density structures at large observation angles from the Sun (with the STEREO Heliospheric Imager instrument). We contribute to this endeavor by deriving analytical formulas concerning a geometric correction for the ICME speed and arrival time for the technique introduced by Davies et al. (2012, ApJ, in press) called Self-Similar Expansion Fitting (SSEF). This model assumes that a circle propagates outward, along a plane specified by a position angle (e.g. the ecliptic), with constant angular half width (lambda). This is an extension to earlier, more simple models: Fixed-Phi-Fitting (lambda = 0 degree) and Harmonic Mean Fitting (lambda = 90 degree). This approach has the advantage that it is possible to assess clearly, in contrast to previous models, if a particular location in the heliosphere, such as a planet or spacecraft, might be expected to be hit by the ICME front. Our correction formulas are especially significant for glancing hits, where small differences in the direction greatly influence the expected speeds (up to 100-200 km/s) and arrival times (up to two days later than the apex). For very wide ICMEs (2 lambda > 120 degree), the geometric correction becomes very similar to the one derived by M\"ostl et al. (2011, ApJ, 741, id. 34) for the Harmonic Mean model. These analytic expressions can also be used for empirical or analytical models to predict the 1 AU arrival time of an ICME by correcting for effects of hits by the flank rather than the apex, if the width and direction of the ICME in a plane are known and a circular geometry of the ICME front is assumed.Comment: 15 pages, 5 figures, accepted for publication in "Solar Physics

Sensitivity of deexcitation energies of superdeformed secondary minima to the density dependence of symmetry energy with the relativistic mean-field theory

The relationship between deexcitation energies of superdeformed secondary minima relative to ground states and the density dependence of the symmetry energy is investigated for heavy nuclei using the relativistic mean field (RMF) model. It is shown that the deexcitation energies of superdeformed secondary minima are sensitive to differences in the symmetry energy that are mimicked by the isoscalar-isovector coupling included in the model. With deliberate investigations on a few Hg isotopes that have data of deexcitation energies, we find that the description for the deexcitation energies can be improved due to the softening of the symmetry energy. Further, we have investigated deexcitation energies of odd-odd heavy nuclei that are nearly independent of pairing correlations, and have discussed the possible extraction of the constraint on the density dependence of the symmetry energy with the measurement of deexcitation energies of these nuclei.Comment: 14 pages, 3 figure

Adaptive vertical layering in TELEMAC-3D

Many processes in environmental hydraulics exhibit sharp spatial gradients of some physical variable(s) in a small localised part of the overall water column. Examples of this include spreading of dense or buoyant plumes and thermal or saline stratification in reservoirs. In this paper, we demonstrate a robust adaptive mesh redistribution (AMR) method coded for TELEMAC-3D. The AMR method aims to capture these sharp gradients without requiring an excessive number of mesh layers or any prior knowledge of the flow structure. Rather than increasing the number of mesh planes in regions of sharp spatial gradients, the idea of mesh redistribution is to maintain a fixed number of planes that move in response to the local solution structure. The movement of the planes is governed by a diffusion equation; an approach that is discussed in Ref. [1]. This approach is similar to that used in the popular GETM software (Ref. [2]). Mesh plane elevations linked to gradients in tracer concentration only are discussed in this paper, although the extension to include velocity shear and/or bathymetry in the equations governing plane placement is expected to be straightforward. We present preliminary results demonstrating that the AMR method can adapt to relatively thin tracer plumes without the increased mesh resolution that would be required with some form of sigma mesh. Comparisons are drawn with an alternative approach in which plane elevations are specified by the user based on some a priori knowledge of the flow structure. The AMR method, which requires neither prior information about the flow nor user input, can be seen to give very similar results for the spreading of dense and buoyant plumes