40,413 research outputs found

    Inference and Optimization of Real Edges on Sparse Graphs - A Statistical Physics Perspective

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    Inference and optimization of real-value edge variables in sparse graphs are studied using the Bethe approximation and replica method of statistical physics. Equilibrium states of general energy functions involving a large set of real edge-variables that interact at the network nodes are obtained in various cases. When applied to the representative problem of network resource allocation, efficient distributed algorithms are also devised. Scaling properties with respect to the network connectivity and the resource availability are found, and links to probabilistic Bayesian approximation methods are established. Different cost measures are considered and algorithmic solutions in the various cases are devised and examined numerically. Simulation results are in full agreement with the theory.Comment: 21 pages, 10 figures, major changes: Sections IV to VII updated, Figs. 1 to 3 replace

    Cascades of Dynamical Transitions in an Adaptive Population

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    In an adaptive population which models financial markets and distributed control, we consider how the dynamics depends on the diversity of the agents' initial preferences of strategies. When the diversity decreases, more agents tend to adapt their strategies together. This change in the environment results in dynamical transitions from vanishing to non-vanishing step sizes. When the diversity decreases further, we find a cascade of dynamical transitions for the different signal dimensions, supported by good agreement between simulations and theory. Besides, the signal of the largest step size at the steady state is likely to be the initial signal.Comment: 4 pages, 8 figure

    Cold-air performance of a 15.41-cm-tip-diameter axial-flow power turbine with variable-area stator designed for a 75-kW automotive gas turbine engine

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    An experimental evaluation of the aerodynamic performance of the axial flow, variable area stator power turbine stage for the Department of Energy upgraded automotive gas turbine engine was conducted in cold air. The interstage transition duct, the variable area stator, the rotor, and the exit diffuser were included in the evaluation of the turbine stage. The measured total blading efficiency was 0.096 less than the design value of 0.85. Large radial gradients in flow conditions were found at the exit of the interstage duct that adversely affected power turbine performance. Although power turbine efficiency was less than design, the turbine operating line corresponding to the steady state road load power curve was within 0.02 of the maximum available stage efficiency at any given speed

    Minimizing Unsatisfaction in Colourful Neighbourhoods

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    Colouring sparse graphs under various restrictions is a theoretical problem of significant practical relevance. Here we consider the problem of maximizing the number of different colours available at the nodes and their neighbourhoods, given a predetermined number of colours. In the analytical framework of a tree approximation, carried out at both zero and finite temperatures, solutions obtained by population dynamics give rise to estimates of the threshold connectivity for the incomplete to complete transition, which are consistent with those of existing algorithms. The nature of the transition as well as the validity of the tree approximation are investigated.Comment: 28 pages, 12 figures, substantially revised with additional explanatio

    Association of antihypertensive monotherapy with serum sodium and potassium levels in Chinese patients

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    <b>Background</b> International guidelines on management of hypertension recommend any major classes of antihypertensive drugs. However, the low prescribing rate of thiazides has been attributed to concerns about electrolyte disturbances and studies between antihypertensive drug classes and hyponatremia/hypokalemia among Chinese patients were scarce. <p></p> <b>Methods</b> From clinical databases we included 2,759 patients who received their first-ever antihypertensive monotherapy from January 2004 to June 2007 in a large territory of Hong Kong. We studied the plasma sodium and potassium levels 8 weeks after prescriptions and factors associated with hyponatremia and hypokalemia by multivariable regression analyses. <p></p> <b>Results</b> Among major antihypertensive drug classes, thiazide users had the lowest sodium level (139.6 mEq/l, 95% confidence interval (CI) 139.3, 140.0, P < 0.001) and patients-prescribed calcium channel blockers (CCBs; 3.92 mEq/l, 95% CI 3.89, 3.95) or thiazide diuretics (3.99 mEq/l, 95% CI 3.93, 4.04) had the lowest potassium levels (P < 0.001). Multivariate analysis reported that advanced age (>/=70 years, odds ratio (OR) 7.49, 95% CI 2.84, 19.8, P < 0.001), male gender (OR 2.38, 95% CI 1.45, 3.91, P < 0.001), and thiazide users (OR 2.42, 95% CI 1.29, 4.56, P = 0.006) were significantly associated with hyponatremia, while renin-angiotensin system (RAS) (OR 0.31, 95% CI 0.13, 0.73, P = 0.008) and beta-blockers (BBs) (OR 0.35, 95% CI 0.23, 0.54, P < 0.001) users were less likely to present with hypokalemia. However, the proportions having normonatremic (95.1%) and normokalemic (89.4%) levels were high. <p></p> <b>Conclusions</b> In view of the low prevalence of hyponatremia and hypokalemia associated with thiazides, physicians should not be deterred from prescribing thiazide diuretics as first-line antihypertensive agents as recommended by most international guidelines
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