62 research outputs found

    A Comprehensive Analysis of MALDI-TOF Spectrometry Data

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    Unmodulated spin chains as universal quantum wires

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    We study a quantum state transfer between two qubits interacting with the ends of a quantum wire consisting of linearly arranged spins coupled by an excitation conserving, time-independent Hamiltonian. We show that if we control the coupling between the source and the destination qubits and the ends of the wire, the evolution of the system can lead to an almost perfect transfer even in the case in which all nearest-neighbour couplings between the internal spins of the wire are equal.Comment: 4 pages, 5 figure

    Networks and Competitiveness in Polish Foreign-owned and Domestic Firms

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    In this study deepens the available knowledge about the networks of Polish manufacturing firms. Among the questions touched upon in this analysis are: Do foreign-owned companies have less developed networks of Polish suppliers than domestically owned companies? What is the role of the science and technology sector in industrial innovation? What benefits do firms derive from cooperation with various types of partners? To achieve a mix of mature and emerging industries, four manufacturing industries were selected for analysis: • electronics • auto/auto parts • pharmaceuticals •food and beverages. The introduction, briefly overviews the recent development and performance of the four industries in Poland. The second section presents case studies of eight firms – two from each of the four industries studied. These case studies were carried out in 2003. The third section, analyzes data collected from a sample of 226 companies in 2004.Networks, upgrading, Poland, manufacturing, competitiveness.

    The role of visceral therapy, Kegel’s muscle, core stability and diet in pelvic support disorders and urinary incontinence — including sexological aspects and the role of physiotherapy and osteopathy

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    Proper diet and physical activity are a form of prevention of female genital prolapse disorders. The causal substrate of pelvic floor dysfunction is multifactorial. Fifty percent of women over the age of 50 have pelvic organ prolapse, often accompanied by urinary incontinence. It is a complicated social and medical (urogynecological and sexological) problem. The authors conducted a literature review on the role of visceral therapy, Kegel and core stability exercises and diet in pelvic support disorders and urinary incontinence. The eligible articles provided insights into sexological factors, as well as the role of osteopathy and physiotherapy. These results provide new insights into the relevance of clinical practice. In addition to standard treatment methods used in gynaecology, sexology, physiotherapy and osteopathy (e.g., visceral therapy), Kegel muscle and core stability exercises are becoming increasingly important. The aim of visceral therapy is to restore the mobility of the organs while reducing increased tension and improving blood and lymph circulation. This has the effect of reducing pain sensations, thereby influencing the function of the uterus and ovaries

    The role of nesfatin and selected molecular factors in various types of endometrial cancer

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    Objectives: Endometrial cancers (ECs) are the most common gynaecological cancers in well developed countries. Diabetes and metabolic syndrome are among the biggest risk factors. Nesfatin-1, the adipokine derivative of NUCB2 (nucleobindin derivative 2) is linked to the clinical course of EC. Molecular factors, including mutations in MLH1 and MHS2 genes, c-MET and ARID1A are also related to prognosis in endometrial cancer. Material and methods: Using sections of paraffin-embedded preparations and immunohistochemistry, the expression of NESF1, MLH1, MSH2,c-MET and ARID1A were examined. Results: In this study on protein expression, EC tissues manifested (although insignificantly) an elevated expression of NESF-1 in type II EC. In type I EC, NESF-1 expression was significantly higher in G1 in comparison to G2 and G3 together. A significantly lower expression of MLH1 was demonstrated in type I EC. Conclusions: The most pronounced expression involved c-MET in all EC I and EC II tissues (in over 80% of cases). A tendency was detected for a high expression of NESF-1 in patients with type II EC, who also exhibited a high expression of MSH2

    Obesity and Cardiometabolic Risk Factors : from Childhood to Adulthood

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    Obesity has become a major epidemic in the 21st century. It increases the risk of dyslipidemia, hypertension, and type 2 diabetes, which are known cardiometabolic risk factors and components of the metabolic syndrome. Although overt cardiovascular (CV) diseases such as stroke or myocardial infarction are the domain of adulthood, it is evident that the CV continuum begins very early in life. Recognition of risk factors and early stages of CV damage, at a time when these processes are still reversible, and the development of prevention strategies are major pillars in reducing CV morbidity and mortality in the general population. In this review, we will discuss the role of well-known but also novel risk factors linking obesity and increased CV risk from prenatal age to adulthood, including the role of perinatal factors, diet, nutrigenomics, and nutri-epigenetics, hyperuricemia, dyslipidemia, hypertension, and cardiorespiratory fitness. The importance of 'tracking' of these risk factors on adult CV health is highlighted and the economic impact of childhood obesity as well as preventive strategies are discussed
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