Hook Up Culture: Changing the Structure of Future Relationships?

Hook up culture is a relatively new phenomenon that is reported to be occurring rampantly on college campuses across the nation. Research tends to focus on the negative implications of hook up culture and the impact it has on college students\u27 well-being. There is limited research exploring if hook up behavior in college is influencing relationship structure in later life, as would be demonstrated by individuals engaging in consensual non-monogamy practices. The present study examined college students\u27 relationship practices to assess if their current relationship status and relationship practices in the past year align with their ideal, future relationship. Results indicate that the overwhelming majority of participants ideally want to become monogamously partnered in the future, regardless of their current relationship practices. Overall these findings indicate that hook up behavior in college is an experiential stage that does not sway college students\u27 ideal relationship preferences

Development of a proof-of-concept space propulsion system for nano-satellite applications using additive manufacturing

In this project, Additive Manufacturing techniques was used to develop a proof-of-concept space propulsion system for nanosatellite applications. The main propulsion unit is made up of a metallic structural housing that is additively manufactured using aluminium powder (AlSi10Mg) on the EOS M290 machine. This housing serves as the reservoir that stores nitrogen gas as the propellant, and other components of the propellant system are assembled into it. The novel feature of the housing is that the propellant feed lines are integrated into the structure. This eliminated welds and joints typically found in conventional propellant storage tank, thereby minimizing leakage whilst simplifying assembly and integration. At the same time, the housing was designed using Design for AM techniques, and this made it possible to increase propellant storage capacity by minimizing support structures. The miniature propulsion nozzle, a key component of the propulsion system, was produced using micro-milling techniques to produce a full 3D converging-diverging profile. A secondary objective of the project was to validate this unique approach by conducting in-space validation experiments to determine the viability of AM in the development of space propulsion applications. Work is currently on-going in the assembly and integration of the proof-of-concept propulsion payload into a 1U Cubesat, where it will serve as the primary payload. This Cubesat mission features a secondary payload which is a commercial off-the-shelf imaging sensor with M12 ruggedized lens that will be tasked with space imaging applications. The current plan is to launch the Cubesat from the International Space Station using the J-SSOD module. The project was carried out by a multi-disciplinary staff/student team comprising faculty members with domain expertise in aerospace, additive manufacturing, avionics/electronics, advanced machining, quality assurance and mechanical testing. The faculty members were responsible for the design, development, and integration of the proof-of-concept propulsion and imaging payloads. The project also provided valuable opportunities for our students to gain hands-on experience in space and satellite engineering. The students hail from the diplomas in aerospace, aviation systems and advanced & digital manufacturing. They were co-located within the Assembly, Integration and Testing lab which features a class 10,000 clean booth. The students supported Cubesat and payload development and integration as well as mechanical testing

Kelch-like ECT2-interacting protein KLEIP regulates late-stage pulmonary maturation via Hif-2α in mice

Respiratory distress syndrome (RDS) caused by preterm delivery is a major clinical problem with limited mechanistic insight. Late-stage embryonic lung development is driven by hypoxia and the hypoxia-inducible transcription factors Hif-1α and Hif-2α, which act as important regulators for lung development. Expression of the BTB-and kelch-domain-containing (BTB-kelch) protein KLEIP (Kelch-like ECT2-interacting protein; also named Klhl20) is controlled by two hypoxia response elements, and KLEIP regulates stabilization and transcriptional activation of Hif-2α. Based on the available data, we hypothesized an essential role for KLEIP in murine lung development and function. Therefore, we have performed a functional, histological, mechanistic and interventional study in embryonic and neonatal KLEIP−/− mice. Here, we show that about half of the KLEIP−/− neonates die due to respiratory failure that is caused by insufficient aeration, reduced septal thinning, reduced glycogenolysis, type II pneumocyte immaturity and reduced surfactant production. Expression analyses in embryonic day (E) 18.5 lungs identified KLEIP in lung capillaries, and showed strongly reduced mRNA and protein levels for Hif-2α and VEGF; such reduced levels are associated with embryonic endothelial cell apoptosis and lung bleedings. Betamethasone injection in pregnant females prevented respiratory failure in KLEIP−/− neonates, normalized lung maturation, vascularization, aeration and function, and increased neonatal Hif-2α expression. Thus, the experimental study shows that respiratory failure in KLEIP−/− neonates is determined by insufficient angiocrine Hif-2α–VEGF signaling and that betamethasone activates this newly identified signaling cascade in late-stage embryonic lung development