Electrolytic refining of gold

At the request of the editor of ELECTROCHEMICAL INDUSTRY, I herewith give some notes on the electrolytic method of gold refining, to supplement the article of Dr. Tuttle (Vol. I, page 157, January, 1903)

Importance of the Physical Environment for Older People

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/111095/1/j.1532-5415.1985.tb05445.x.pd

Memórias de Gretchen Wohlwill (exerto) : Tradução

A pintora e gravurista Gretchen Wohlwill (1878 - 1962) chegou a Portugal como refugiada (1940) dada a perseguição que lhe movia o nacional-socialismo, para se juntar ao irmão, Friedrich Wohlwill, prestigiado médico patologista e professor universitário, que a precedera no exílio e rapidamente se vira reconhecido em Portugal, onde foi médico e Professor da Faculdade de Medicina. Oriunda de uma família de reconhecidos académicos, de origem judaica e de orientação laica, Gretchen Wohlwill frequentara a escola de arte de Valeska Röver em Hamburgo e a Academia Matisse em Paris, antes de se destacar como pintora e professora de arte num liceu feminino e membro fundador do movimento da Secessão de Hamburgo (1919)

On growth curves and mixture models

The multilevel model of change and the latent growth model are flexible means to describe all sorts of population heterogeneity with respect to growth and development, including the presence of sub-populations. The growth mixture model is a natural extension of these models. It comes at hand when information about sub-populations is missing and researchers nevertheless want to retrieve developmental trajectories from sub-populations. We argue that researchers have to make rather strong assumptions about the sub-populations or latent trajectory classes in order to retrieve existing population differences. A simulated example is discussed, showing that a sample of repeated measures drawn from two sub-populations easily leads to the mistaken inference of three sub-populations, when assumptions are not met. The merits of methodological advises on this issue are discussed. It is concluded that growth mixture models should be used with understanding, and offer no free way to growth patterns in unknown sub-populations. Copyright © 2006 John Wiley & Sons, Ltd

A Case of Infantile Alexander Disease Accompanied by Infantile Spasms Diagnosed by DNA Analysis

Alexander disease (AD) is a rare leukodystrophy of the central nervous system of unknown etiology. AD is characterized by progressive failure of central myelination and the accumulation of Rosenthal fibers in astrocytes, and is inevitably lethal in nature. Symptomatically, AD is associated with leukoencephalopathy with macrocephaly, seizures, and psychomotor retardation in infants, and usually leads to death within the first decade. Its characteristic magnetic resonance imaging (MRI) findings have been described as demyelination predominantly in the frontal lobe. Moreover, dominant mutations in the GFAP gene, coding for glial fibrillary acidic protein (GFAP), a principal astrocytic intermediate filament protein, have been shown to lead to AD. The disease can now be detected by genetic diagnosis. We report the Korean case of an 8-month-old male patient with AD. He was clinically characterized due to the presence of psychomotor retardation, megalencephaly, spasticity, and recurrent seizures including infantile spasms which is a remarkable presentation. Demyelination in the frontal lobe and in a portion of the temporal lobe was demonstrated by brain MRI. Moreover, DNA analysis of peripheral blood showed the presence of a R239L mutation in the GFAP gene, involving the replacement of guanine with thymine

Impact of urban nature: A theoretical analysis

The stresses and strains of the urban environment are widely acknowledged. The means for recovery, for recuperation, are perhaps less evident. In particular, the role of environmental configurations in this process is often neglected in the measurement of quality of life.The urban natural environment can provide the setting for such restorative experiences, both physically and conceptually. A theoretical analysis is presented that focuses on the importance of fascination and coherence as essential processes in the powerful effects of the nature context. When these are both afforded by the setting, many of the benefits available in more remote natural settings may be available in the nearby urban context as well. The bits and pieces of urban nature are significant not only in terms of active recreational encounters. The view of trees and birds, the thought of spring to come, and the plans for summer's window box can all help in the restorative experience.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/24680/1/0000099.pd

Simultaneous genetic analysis of longitudinal means and covariance structure in the simplex model using twin data

A longitudinal model based on the simplex model is presented to analyze simultaneously means and covariance structure using univariate longitudinal twin data. The objective of the model is to decompose the mean trend into components which can be attributed to those genetic and environmental factors which give rise to phenotypic individual differences and a component of unknown constitution which does not involve individual differences. Illustrations are given using simulated data and repeatedly measured weight obtained in a sample of 82 female twin pairs on sbc occasions. KEY WORDS: repeated measures; genetic and environmental covariance structure; mean trend; longitudinal twin data; genetic simplex mode; LISREL

Use of the physical environment to support everyday activities for people with dementia: A systematic review

Difficulty with everyday activities is a key symptom and defining feature of dementia, relating to subjective reports of well-being and overall quality of life. One way to support individuals in their daily activities is by modifying the physical environment to make it easier to interact with during activity performance. This systematic review explores the range of studies available using physical environmental strategies to support performance in everyday activities for people with dementia. Seventy-two relevant studies were identified by the search. Physical environmental strategies included changes to the global environment and to architectural features, use of moveable environmental aids and tailored individual approaches. Strategies supported general everyday activity functioning (N = 19), as well as specific activities, particularly mealtimes (N = 15) and orientation in space (N = 16); however, few studies were found that focused on aspects of personal care such as dressing (N = 1) and showering or the preferred hobbies of individuals (N = 0). Overall, there appeared to be a lack of research within private home environments, and of studies which specify the dementia syndrome or the whole neuropsychological profile of people with dementia. More work is needed to extend theoretical understandings of how people with dementia interact with their environments so that these spaces can be designed to further support activities of daily living performance. Future work in this field could also incorporate the perspectives and preferences of those living with dementia.The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This review was supported by a studentship from Brunel University London. The studentship is attached to a grant from the ESRC-NIHR (UK) (Grant ES/L001810/1). Grant title: Seeing what they see: compensating for cortical visual dysfunction in Alzheimer’s Disease. SC is also supported by the NIHR Queen Square Dementia Biomedical Research Unit and an Alzheimer’s Research UK Senior Research Fellowship