439 research outputs found

    Accretion physics of AM Herculis binaries, I. Results from one-dimensional stationary radiation hydrodynamics

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    We have solved the one-dimensional stationary two-fluid hydrodynamic equations for post-shock flows on accreting magnetic white dwarfs simultaneous with the fully frequency and angle-dependent radiative transfer for cyclotron radiation and bremsstrahlung. Magnetic field strengths B = 10 to 100 MG are considered. At given B, this theory relates the properties of the emission region to a single physical parameter, the mass flow density (or accretion rate per unit area). We present the normalized temperature profiles and fit formulae for the peak electron temperature, the geometrical shock height, and the column density of the post-shock flow. The results apply to pillbox-shaped emission regions. With a first-order temperature correction they can also be used for narrower columns provided they are not too tall.Comment: 10 pages with 10 Postscript figures, accepted for publication in Astronomy & Astrophysics. The source file contains Table 1a/b in ASCII forma

    Simulation System for the Wendelstein 7-X Safety Control System

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    The Wendelstein 7-X (W7-X) Safety Instrumented System (SIS) ensures personal safety and investment protection. The development and implementation of the SIS are based on the international safety standard for the process industry sector, IEC 61511. The SIS exhibits a distributed and hierarchical organized architecture consisting of a central Safety System (cSS) on the top and many local Safety Systems (lSS) at the bottom. Each technical component or diagnostic system potentially hazardous for the staff or for the device is equipped with an lSS. The cSS is part of the central control system of W7-X. Whereas the lSSs are responsible for the safety of each individual component, the cSS ensures safety of the whole W7-X device. For every operation phase of the W7-X experiment hard- and software updates for the SIS are mandatory. New components with additional lSS functionality and additional safety signals have to be integrated. Already established safety functions must be adapted and new safety functions have to be integrated into the cSS. Finally, the safety programs of the central and local safety systems have to be verified for every development stage and validated against the safety requirement specification. This contribution focuses on the application of a model based simulation system for the whole SIS of W7-X. A brief introduction into the development process of the SIS and its technical realization will be give followed by a description of the design and implementation of the SIS simulation system using the framework SIMIT (Siemens). Finally, first application experiences of this simulation system for the preparation of the SIS for the upcoming operation phase OP 1.2b of W7-X will be discussed

    System and market failures: the unavailability of magnesium sulphate for the treatment of eclampsia and pre-eclampsia in Mozambique and Zimbabwe.

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    Low cost and effective drugs, such as magnesium sulphate, need to be included in initiatives to improve access to essential medicines in Afric

    Method and Apparatus for Jet-Assisted Drilling or Cutting

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    An abrasive cutting or drilling system, apparatus and method, which includes an upstream supercritical fluid and/or liquid carrier fluid, abrasive particles, a nozzle and a gaseous or low-density supercritical fluid exhaust abrasive stream. The nozzle includes a throat section and, optionally, a converging inlet section, a divergent discharge section, and a feed section

    Small Angle Neutron Scattering from D2O–H2O Nanodroplets and Binary Nucleation Rates in A Supersonic Nozzle

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    Small angle neutron scattering (SANS) experiments were used to characterize binary nanodroplets composed of D2O and H2O. The droplets were formed by expanding dilute mixtures of condensible vapor in a N2 carrier gas through a supersonic nozzle, while maintaining the onset of condensation at a fixed position in the nozzle. It is remarkable, given the small coherent scattering length density of light water, that even the pure H2O aerosol gave a scattering signal above background. The scattering spectra were analyzed assuming a log-normal distribution of droplets. On average, the geometric radius of the nanodroplets rg was rg=13 (±1) nm, the polydispersity ln σr was ln σr=0.19 (±0.07), and the number density N was N=(2±0.2)⋅1011 cm−3. The aerosol volume fractions derived from the SANS measurements are consistent with those derived from the pressure trace experiments, suggesting that the composition of the droplets was close to that of the initial condensible mixture. A quantitative analysis of the scattering spectra as a function of the isotopic composition gave further evidence that the binary droplets exhibit ideal mixing behavior. Because both the stagnation temperature T0 and the location of onset were fixed, the temperature corresponding to the maximum nucleation rate was constant at TJ max=229 (±1) K. Thus, the experiments let us estimate the isothermal peak nucleation rates as a function of the isotopic composition. The nucleation rates were found to be essentially constant with Jmax equal to (3.6±0.5)⋅1016 cm−3 s−1 at a mean supersaturation of 44 (±3)

    H2O–D2O Condensation in A Supersonic Nozzle

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    We examined the condensation of H2O, D2O, and four intermediate mixtures (20, 40, 60, and 80 mol % D2O) in a supersonic nozzle. Because the physical and chemical properties of protonated and deuterated water are so similar, this system is ideal for studying the change in condensation behavior as a function of condensible composition. In our experiments dilute mixtures of condensible vapor in N2 are expanded from three different stagnation temperatures resulting in a broad range of onset temperatures (190–238 K) and pressures (27–787 kPa). For a fixed stagnation temperature, the partial pressure required to maintain the onset of condensation at a given location or temperature in the nozzle is consistently higher for H2O than for D2O. In contrast, the supersaturation at fixed onset temperature is usually higher for D2O than for H2O and this difference increases toward lower temperature. The partial pressure at onset for the intermediate mixtures varied linearly between the values observed for the pure components in this ideal system

    GALEX, Optical and IR Light Curves of MQ Dra: UV Excesses at Low Accretion Rates

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    Ultraviolet light curves constructed from NUV and FUV detectors on GALEX reveal large amplitude variations during the orbital period of the Low Accretion Rate Polar MQ Dra (SDSSJ1553+55). This unexpected variation from a UV source is similar to that seen and discussed in the Polar EF Eri during its low state of accretion, even though the accretion rate in MQ Dra is an order of magnitude lower than even the low state of EF Eri. The similarity in phasing of the UV and optical light curves in MQ Dra imply a similar location for the source of light. We explore the possibilities of hot spots and cyclotron emission with simple models fit to the UV, optical and IR light curves of MQ Dra. To match the GALEX light curves with a single temperature circular hot spot requires different sizes of spots for the NUV and FUV, while a cyclotron model that can produce the optical harmonics with a magnetic field near 60 MG requires multipoles with fields > 200 MG to match the UV fluxes.Comment: accepted for ApJ; 15 pages, 7 tables, 8 fig

    Validation of the Dutch Version of the Plymouth Sensory Imagery Questionnaire

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    Mental imagery plays an important role in the onset and maintenance of psychological disorders as well as their treatment. Therefore, a reliable and valid measure of mental imagery is essential. Andrade and colleagues (2014) developed the Plymouth Sensory Imagery Questionnaire (PsiQ), which contains 35 items (long version) or 21 items (shortened version) measuring the vividness of mental imagery in seven different modalities: vision, sound, smell, taste, touch, bodily sensation, and emotion. Andrade et al. reported a seven-factor structure corresponding to the different modalities for both versions rather than a one-factor model measuring general mental imagery. The current paper reports on the translation and validation of the Dutch version of the PsiQ (PsiQ-NL-35 and PsiQ-NL-21). In two independent samples (student and mixed), the PsiQ-NL-35 showed excellent internal consistency, adequate model fit for the seven-factor model, and a poor fit for the one-factor model. Test-retest reliability (Study 1, student sample) was good. Construct validity (Study 2, mixed sample) was adequate. The PsiQ-NL-21 also showed excellent internal consistency, good test-retest reliability, adequate seven-factor model fit, and adequate construct validity. Measurement invariance between the Dutch and the English version was found, implying that both versions measure the same construct

    Hypothalamus proteomics from mouse models with obesity and anorexia reveals therapeutic targets of appetite regulation

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    Objective: This study examined the proteomic profile of the hypothalamus in mice exposed to a high-fat diet (HFD) or with the anorexia of acute illness. This comparison could provide insight on the effects of these two opposite states of energy balance on appetite regulation.Methods: Four to six-week-old male C56BL/6J mice were fed a normal (control 1 group; n=7) or a HFD (HFD group; n=10) for 8 weeks. The control 2 (n=7) and lipopolysaccharide (LPS) groups (n=10) were fed a normal diet for 8 weeks before receiving an injection of saline and LPS, respectively. Hypothalamic regions were analysed using a quantitative proteomics method based on a combination of techniques including iTRAQ stable isotope labeling, orthogonal two-dimensional liquid chromatography hyphenated with nanospray ionization and high-resolution mass spectrometry. Key proteins were validated with quantitative PCR.Results: Quantitative proteomics of the hypothalamous regions profiled a total of 9249 protein groups (q<0.05). Of these, 7718 protein groups were profiled with a minimum of two unique peptides for each. Hierachical clustering of the differentiated proteome revealed distinct proteomic signatures for the hypothalamus under the HFD and LPS nutritional conditions. Literature research with in silico bioinformatics interpretation of the differentiated proteome identified key biological relevant proteins and implicated pathways. Furthermore, the study identified potential pharmacologic targets. In the LPS groups, the anorexigen pro-opiomelanocortin was downregulated. In mice with obesity, nuclear factor-?B, glycine receptor subunit alpha-4 (GlyR) and neuropeptide Y levels were elevated, whereas serotonin receptor 1B levels decreased.Conclusions: High-precision quantitative proteomics revealed that under acute systemic inflammation in the hypothalamus as a response to LPS, homeostatic mechanisms mediating loss of appetite take effect. Conversely, under chronic inflammation in the hypothalamus as a response to HFD, mechanisms mediating a sustained ‘perpetual cycle’ of appetite enhancement were observed. The GlyR protein may constitute a novel treatment target for the reduction of central orexigenic signals in obesity

    The Cyclotron Fundamental Exposed in the High-Field Magnetic Variable V884 Her

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    High-quality phase-resolved optical spectropolarimetry is presented for the magnetic cataclysmic variable V884 Her. The overall circular polarization during active accretion states is low and only slightly variable in the range 5000-8000A. However, the polarization is highly structured with wavelength, showing very broad polarization humps, narrow features that are associated with weak absorption lines in the total spectral flux, and sharp reversals across each major emission line. The polarization reversals arise from Zeeman splitting in the funnel gas in a longitudinal magnetic field B~30kG. The set of narrow, polarized absorption features matches the Zeeman pattern of hydrogen for a nearly uniform magnetic field of B=150MG, indicating that the features are "halo" absorption lines formed in a relatively cool reversing layer above the shock. With this identification, the broad polarization humps centered near 7150A and below 4000A are assigned to cyclotron emission from the fundamental and first harmonic (n=2), respectively. V884 Her is only the second AM Her system known with a field exceeding 100MG, and the first case in which the cyclotron fundamental has been directly observed from a magnetic white dwarf.Comment: 14 pages, 6 figures, LaTeX, to appear in The Astrophysical Journal, Part
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