Experiments on identification and control of inflow disturbances in contracting streams

Vorticity from all surfaces and isolated objects in the vicinity of the fan intake, including the outside surfaces of the fan housing, were identified as the major sources for disturbances leading to blade passing frequency noise. The previously proposed mechanism based on atmospheric turbulence is refuted. Flow visualization and hot wire techniques were used in three different facilities to document the evolution of various types of disturbances, including the details of the mean flow and turbulence characteristics. The results suggest that special attention must be devoted to the design of the inlet and that geometric modeling may not lead to adequate simulation of the in flight characteristics. While honeycomb type flow manipulators appear to be effective in reducing some of the disturbances, higher pressure drop devices that generate adequate turbulence, for mixing of isolated nonuniformities, may be necessary to suppress the remaining disturbances. The results are also applicable to the design of inlets of open return wind tunnels and similar flow facilities

Asymptotic description of solutions of the exterior Navier Stokes problem in a half space

We consider the problem of a body moving within an incompressible fluid at constant speed parallel to a wall, in an otherwise unbounded domain. This situation is modeled by the incompressible Navier-Stokes equations in an exterior domain in a half space, with appropriate boundary conditions on the wall, the body, and at infinity. We focus on the case where the size of the body is small. We prove in a very general setup that the solution of this problem is unique and we compute a sharp decay rate of the solution far from the moving body and the wall

Effect of substrate thermal resistance on space-domain microchannel

In recent years, Fluorescent Melting Curve Analysis (FMCA) has become an almost ubiquitous feature of commercial quantitative PCR (qPCR) thermal cyclers. Here a micro-fluidic device is presented capable of performing FMCA within a microchannel. The device consists of modular thermally conductive blocks which can sandwich a microfluidic substrate. Opposing ends of the blocks are held at differing temperatures and a linear thermal gradient is generated along the microfluidic channel. Fluorescent measurements taken from a sample as it passes along the micro-fluidic channel permits fluorescent melting curves to be generated. In this study we measure DNA melting temperature from two plasmid fragments. The effects of flow velocity and ramp-rate are investigated, and measured melting curves are compared to those acquired from a commercially available PCR thermocycler

A Weighted Estimate for the Square Function on the Unit Ball in \C^n

We show that the Lusin area integral or the square function on the unit ball of \C^n, regarded as an operator in weighted space $L^2(w)$ has a linear bound in terms of the invariant $A_2$ characteristic of the weight. We show a dimension-free estimate for the ``area-integral'' associated to the weighted $L^2(w)$ norm of the square function. We prove the equivalence of the classical and the invariant $A_2$ classes.Comment: 11 pages, to appear in Arkiv for Matemati

A Renormalization Group for Hamiltonians: Numerical Results

We describe a renormalization group transformation that is related to the breakup of golden invariant tori in Hamiltonian systems with two degrees of freedom. This transformation applies to a large class of Hamiltonians, is conceptually simple, and allows for accurate numerical computations. In a numerical implementation, we find a nontrivial fixed point and determine the corresponding critical index and scaling. Our computed values for various universal constants are in good agreement with existing data for area-preserving maps. We also discuss the flow associated with the nontrivial fixed point.Comment: 11 Pages, 2 Figures. For future updates, check ftp://ftp.ma.utexas.edu/pub/papers/koch

Scaling of the Critical Function for the Standard Map: Some Numerical Results

The behavior of the critical function for the breakdown of the homotopically non-trivial invariant (KAM) curves for the standard map, as the rotation number tends to a rational number, is investigated using a version of Greene's residue criterion. The results are compared to the analogous ones for the radius of convergence of the Lindstedt series, in which case rigorous theorems have been proved. The conjectured interpolation of the critical function in terms of the Bryuno function is discussed.Comment: 26 pages, 3 figures, 13 table

EXPOSURE OF THE SWISS POPULATION BY RADIODIAGNOSTICS: 2013 REVIEW.

In 2013, a nationwide investigation was conducted in Switzerland to establish the population's exposure from medical X rays. A hybrid approach was used combining the Raddose database accessible on-line by the participating practices and the Swiss medical tariffication system for hospitals. This study revealed that the average annual number of examinations is 1.2 per inhabitant, and the associated annual effective dose is 1.4 mSv. It also showed that computed tomography is the most irradiating modality and that it delivers 70 % of the total dose. The annual effective dose per inhabitant registered a 17 % increase in 5 y and is comparable with what was recently reported in neighbouring countries

Base-pair neutral homozygotes can be discriminated by calibrated high-resolution melting of small amplicons

Genotyping by high-resolution melting analysis of small amplicons is homogeneous and simple. However, this approach can be limited by physical and chemical components of the system that contribute to intersample melting variation. It is challenging for this method to distinguish homozygous G::C from C::G or A::T from T::A base-pair neutral variants, which comprise ∼16% of all human single nucleotide polymorphisms (SNPs). We used internal oligonucleotide calibrators and custom analysis software to improve small amplicon (42–86 bp) genotyping on the LightScanner®. Three G/C (PAH c.1155C>G, CHK2 c.1-3850G>C and candidate gene BX647987 c.261+22,290C>G) and three T/A (CPS1 c.3405-29A>T, OTC c.299-8T>A and MSH2 c.1511-9A>T) human single nucleotide variants were analyzed. Calibration improved homozygote genotyping accuracy from 91.7 to 99.7% across 1105 amplicons from 141 samples for five of the six targets. The average Tm standard deviations of these targets decreased from 0.067°C before calibration to 0.022°C after calibration. We were unable to generate a small amplicon that could discriminate the BX647987 c.261+22,290C>G (rs1869458) SNP, despite reducing standard deviations from 0.086°C to 0.032°C. Two of the sites contained symmetric nearest neighbors adjacent to the SNPs. Unexpectedly, we were able to distinguish these homozygotes by Tm even though current nearest neighbor models predict that the two homozygous alleles would be identical