Junior Recital: Devin Aaron Witt, bass trombone

This recital is presented in partial fulfillment of requirements for the degree Bachelor of Music in Performance. Mr. Witt studies bass trombone with Brian Hecht and Nathan Zgonc.https://digitalcommons.kennesaw.edu/musicprograms/1921/thumbnail.jp

Senior Recital: Jonathan Fallin, trumpet

This recital is presented in partial fulfillment of requirements for the degree Bachelor of Music in Music Education. Mr. Fallin studies trumpet with Dr. Douglas Lindsey.https://digitalcommons.kennesaw.edu/musicprograms/1026/thumbnail.jp

Senior Recital: Connor Osburn, horn

This recital is presented in partial fulfillment of requirements for the degree Bachelor of Music in Performance. Mr. Connor studies horn with Tom Witte.https://digitalcommons.kennesaw.edu/musicprograms/1257/thumbnail.jp

Forensic discrimination of differentially sourced animal blood using a bottom-Up proteomics based MALDI MS approach

Recently published work has reported the development and application of a bottom-up proteomic approach to distinguish between human and animal blood (down to animal species level), by rapid screening using Matrix Assisted Laser Desorption Ionisation Mass Spectrometry (MALDI MS). In that study, it was additionally observed that intravenous animal blood exhibits different spectral profiles from blood collected within the animal chest cavity as well as from the diluted blood collected within packets of meat. In this follow-up study we explored the resulting hypothesis that, depending on how blood is shed or collected, protein biomarker profiles vary to the extent of systematically permitting a distinction between possible sources of blood (for example, flesh wound versus packaged meat). This intelligence may be important in reconstructing the dynamics of the crime. The combination of statistical analysis and tandem mass spectrometry has yielded additional animal blood markers as well as confirming the ability to correctly determine the animal species from which blood derived, regardless of the retailer selling it (amongst the five investigated). These data confirm the initial hypothesis and demonstrate the opportunity for the proteomics-MALDI combined approach to provide additional intelligence to the investigation of violent crimes when examining blood evidence

2016-17 Concerto Competition Final Round

The 2016-17 Concerto Competition culminates in this performance featuring students competing to perform as a featured soloist with the KSU Symphony Orchestra on April 26, 2017.https://digitalcommons.kennesaw.edu/musicprograms/1695/thumbnail.jp

Observations of Far-Ultraviolet Diffuse Emission from the Small Magellanic Cloud

We report the first observations of far-ultraviolet (FUV: 1000 -- 1150 \AA) diffuse radiation from the Small Magellanic Cloud (SMC) using observations from the {\em Far Ultraviolet Spectroscopic Explorer (FUSE)}. The strength of FUV diffuse surface brightness in the SMC ranges from the detection limit of 2000 photons cm$^{-2}$ s$^{-1}$ sr$^{-1}$ \AA$^{-1}$ to a maximum of $3 \times 10^{5}$ photons cm$^{-2}$ s$^{-1}$ sr$^{-1}$ \AA$^{-1}$ at 1004 \AA. The contribution of diffuse emission to the total radiation field was found to be 34% at 1004 \AA to 44% at 1117 \AA with a maximum observed uncertainty of 30%. There is a striking difference between the FUV diffuse fraction from the SMC and the Large Magellanic Cloud (LMC) with the SMC fraction being higher probable because the higher dust albedo. The FUV diffuse emission correlates with H$\alpha$ emission in the H {\small II} regions of the SMC.Comment: Accepted for publication in Ap

Therapeutic Effect of Arsenicum album on Leukocytes

The therapeutic effects of homoeopathic Arsenicum album potencies were investigated in-vitro, using a continuous cell line (MT4), pre-intoxicated with arsenic trioxide (As2O3), and then treated with succussed and unsuccussed homoeopathic potencies, 6CH, 30CH and 200CH. This study aimed to verify the homoeopathic law of similars and to determine whether potencies diluted beyond Avogadro’s constant had physiological effects on cells; whether various potencies would cause different effects as suggested by the concept of hormesis; whether succussed and unsuccussed homoeopathic potencies had different effects on the cells; and to establish whether a biotechnological method could be used to evaluate the above. As2O3 was used to pre-intoxicate and the MTT assay was used to measure the percentage cytotoxicity and half maximal inhibitory concentration (IC50) of the cells. The homoeopathic potencies of Arsenicum album (6CH, 30CH and 200CH) were prepared by either succussing or allowing to diffuse for 30 s. After pre-intoxication of the MT4 cells with the IC50 As2O3 and treatment with succussed and unsuccussed Arsenicum album (6CH-200CH), the cell viability increased with increasing potency from 81% to 194% (over 72 h). The treatments and the times of exposure were found to be statistically significant determinants of cell viability, whereas succussion did not cause any significant variation in the results. The study provided evidence that a biotechnological method (namely cell viability) may be used to scientifically evaluate the physiological effects of homoeopathic potencies on human cells; it confirmed that the homoeopathic potencies did have therapeutic effects; and that succussion was not required in the potentization method in order to produce a curative remedy

MACE-OFF23: Transferable Machine Learning Force Fields for Organic Molecules

Classical empirical force fields have dominated biomolecular simulation for over 50 years. Although widely used in drug discovery, crystal structure prediction, and biomolecular dynamics, they generally lack the accuracy and transferability required for predictive modelling. In this paper, we introduce MACE-OFF23, a transferable force field for organic molecules created using state-of-the-art machine learning technology and first-principles reference data computed with a high level of quantum mechanical theory. MACE-OFF23 demonstrates the remarkable capabilities of local, short-range models by accurately predicting a wide variety of gas and condensed phase properties of molecular systems. It produces accurate, easy-to-converge dihedral torsion scans of unseen molecules, as well as reliable descriptions of molecular crystals and liquids, including quantum nuclear effects. We further demonstrate the capabilities of MACE-OFF23 by determining free energy surfaces in explicit solvent, as well as the folding dynamics of peptides. Finally, we simulate a fully solvated small protein, observing accurate secondary structure and vibrational spectrum. These developments enable first-principles simulations of molecular systems for the broader chemistry community at high accuracy and low computational cost

Sharing Space: The Presence of Other Bodies Extends the Space Judged as Near

Background: As social animals we share the space with other people. It is known that perceived extension of the peripersonal space (the reaching space) is affected by the implicit representation of our own and other's action potentialities. Our issue concerns whether the co-presence of a body in the scene influences our extrapersonal space (beyond reaching distance) categorization. Methodology/Principal Findings: We investigated, through 3D virtual scenes of a realistic environment, whether egocentric spatial categorization can be influenced by the presence of another human body (Exp. 1) and whether the effect is due to her action potentialities or simply to her human-like morphology (Exp. 2). Subjects were asked to judge the location ("Near" or "Far") of a target object located at different distances from their egocentric perspective. In Exp. 1, the judgment was given either in presence of a virtual avatar (Self-with-Other), or a non-corporeal object (Self-with-Object) or nothing (Self). In Exp. 2, the Self condition was replaced by a Self-with-Dummy condition, in which an inanimate body (a wooden dummy) was present. Mean Judgment Transition Thresholds (JTTs) were calculated for each subject in each experimental condition. Self-with-Other condition induced a significant extension of the space judged as "Near" as compared to both the Selfwith- Object condition and the Self condition. Such extension was observed also in Exp. 2 in the Self-with-Dummy condition. Results suggest that the presence of others impacts on our perception of extrapersonal space. This effect holds also when the other is a human-like wooden dummy, suggesting that structural and morphological shapes resembling human bodies are sufficient conditions for the effect to occur. Conclusions: The observed extension of the portion of space judged as near could represent a wider portion of "accessible" space, thus an advantage in the struggle to survive in presence of other potential competing individuals