Maritime Strategy and Naval Innovation (Continuation)

NPS NRP Executive SummaryMaritime Strategy and Naval Innovation (Continuation)N3/N5 - Information, Plans & StrategyThis research is supported by funding from the Naval Postgraduate School, Naval Research Program (PE 0605853N/2098). https://nps.edu/nrpChief of Naval Operations (CNO)Approved for public release. Distribution is unlimited.

Maritime Strategy and Naval Innovation (Continuation)

NPS NRP Project PosterMaritime Strategy and Naval Innovation (Continuation)N3/N5 - Information, Plans & StrategyThis research is supported by funding from the Naval Postgraduate School, Naval Research Program (PE 0605853N/2098). https://nps.edu/nrpChief of Naval Operations (CNO)Approved for public release. Distribution is unlimited.

NPS Seapower Conversations - Global Geopolitics [video]

This Seapower Conversation is actually the Kickoff Event for the 2021 Warfare Innovation Continuum (WIC) - HYBRID FORCE 2045. A panel discussion consisiting of reknowned faculty from the Naval Postgraduate School, Graduate School of International and Defense Studies (IDS), Department of National Security Affairs, and Department of War Studies King's College London will highlight recent research they have conducted and writings they have completed in the Geopolitical arena. This event will be broadcast via Microsoft Teams and NPS Livestream. Moderated by CAPT Douglas E. Otte, USN(Ret.), Senior Lecturer, Operations Research, NPS

A Reflection on Teaching and Learning in a Community Literacies Graduate Course

Th is article outlines one potential model for a graduate–level course in community literacy studies. Ellen Cushman and Jeffrey Grabill taught this course for the first time at Michigan State University in the spring of 2007. In this article our colleagues with varying disciplinary backgrounds reflect on the course, its readings, and their theoretical and practical understanding surrounding many of the central questions of this new discipline: what is a community? What is literacy? What is community literacy? And what does it mean to practice “community literacy”—to write, to speak, and so on? After a wide discussion of course experience from several student colleagues in the course, Cushman and Grabill reflect on their course objectives and point toward future incarnations of the course

Transatlantic intelligence and security cooperation

Despite recent advances in transatlantic intelligence and security cooperation, significant problems remain. The bombings in Madrid in March 2004 have demonstrated how terrorists and criminals can continue to exploit the limits of hesitant or partial exchange to dangerous effect. Intelligence and security cooperation remain problematic because of the fundamental tension between an increasingly networked world, which is ideal terrain for the new religious terrorism, and highly compartmentalized national intelligence gathering. If cooperation is to improve, we require a better mutual understanding about the relationship between privacy and security to help us decide what sort of intelligence should be shared. This is a higher priority than building elaborate new structures. While most practical problems of intelligence exchange are ultimately resolvable, the challenge of agreeing what the intelligence means in broad terms is even more problematic. The last section of this article argues that shared NATO intelligence estimates would be difficult to achieve and of doubtful value

Maritime Strategy and Naval Innovation (Continuation)

NPS NRP Project PosterThis project is a continuation of ongoing support by NPS to the work of N50 to further refining and improving the Navy's strategy development and implementation processes. This will be the fourth year of support to the N50. Under the auspices of this project, NPS faculty in the Department of National Security Affairs can: (1) support ongoing short-study and paper review efforts in the N50; and (2) build content and scholarship in the form of books and papers on the relationship between maritime strategy and naval innovation. In the FY18 phase of the project, a team of NPS professors is producing a scholarly volume in partnership with King's College at the University of London on the topic: Maritime Strategy and Naval Innovation. 1. How can the Navy best structure itself to ensure that that its strategy development and implementation process can reflect changes in the dynamic strategic environment. 2. How can the Navy create a culture of innovation that ensures it has the human capital necessary to keep the organization head of its adversaries in the timeless adapt-react cycle that drives organizational and national behavior? 3. What are the issues in Eurasia that will define the maritime environment over the rest of the 21st century. How can the Navy anticipate these changes in its models for planning and force structure? 4. What are political dynamics facing the Navy and the nation in Eurasia that will define interactions on the high seas? Content preparation and analysis by a team of NPS faculty, to include James Russell, Jim Wirtz, Tom Young, Christopher Twomey and Donald Abenheim. The deliverable out of this project will be a book that can be used to educate future naval strategists like those in the NPS NSA 688 curriculum on Strategic Studies. The FY19 phase will see the same team produce a volume: The Struggle for Mastery in Eurasia.This project is a continuation of ongoing support by NPS to the work of N50 to further refining and improving the Navy's strategy development and implementation processes. This will be the fourth year of support to the N50. Under the auspices of this project, NPS faculty in the Department of National Security Affairs can: (1) support ongoing short-study and paper review efforts in the N50; and (2) build content and scholarship in the form of books and papers on the relationship between maritime strategy and naval innovation. In the FY18 phase of the project, a team of NPS professors is producing a scholarly volume in partnership with King's College at the University of London on the topic: Maritime Strategy and Naval Innovation. 1. How can the Navy best structure itself to ensure that that its strategy development and implementation process can reflect changes in the dynamic strategic environment. 2. How can the Navy create a culture of innovation that ensures it has the human capital necessary to keep the organization head of its adversaries in the timeless adapt-react cycle that drives organizational and national behavior? 3. What are the issues in Eurasia that will define the maritime environment over the rest of the 21st century. How can the Navy anticipate these changes in its models for planning and force structure? 4. What are political dynamics facing the Navy and the nation in Eurasia that will define interactions on the high seas? Content preparation and analysis by a team of NPS faculty, to include James Russell, Jim Wirtz, Tom Young, Christopher Twomey and Donald Abenheim. The deliverable out of this project will be a book that can be used to educate future naval strategists like those in the NPS NSA 688 curriculum on Strategic Studies. The FY19 phase will see the same team produce a volume: The Struggle for Mastery in Eurasia.This project is a continuation of ongoing support by NPS to the work of N50 to further refining and improving the Navy's strategy development and implementation processes. This will be the fourth year of support to the N50. Under the auspices of this project, NPS faculty in the Department of National Security Affairs can: (1) support ongoing short-study and paper review efforts in the N50; and (2) build content and scholarship in the form of books and papers on the relationship between maritime strategy and naval innovation. In the FY18 phase of the project, a team of NPS professors is producing a scholarly volume in partnership with King's College at the University of London on the topic: Maritime Strategy and Naval Innovation. 1. How can the Navy best structure itself to ensure that that its strategy development and implementation process can reflect changes in the dynamic strategic environment. 2. How can the Navy create a culture of innovation that ensures it has the human capital necessary to keep the organization head of its adversaries in the timeless adapt-react cycle that drives organizational and national behavior? 3. What are the issues in Eurasia that will define the maritime environment over the rest of the 21st century. How can the Navy anticipate these changes in its models for planning and force structure? 4. What are political dynamics facing the Navy and the nation in Eurasia that will define interactions on the high seas? Content preparation and analysis by a team of NPS faculty, to include James Russell, Jim Wirtz, Tom Young, Christopher Twomey and Donald Abenheim. The deliverable out of this project will be a book that can be used to educate future naval strategists like those in the NPS NSA 688 curriculum on Strategic Studies. The FY19 phase will see the same team produce a volume: The Struggle for Mastery in Eurasia.This project is a continuation of ongoing support by NPS to the work of N50 to further refining and improving the Navy's strategy development and implementation processes. This will be the fourth year of support to the N50. Under the auspices of this project, NPS faculty in the Department of National Security Affairs can: (1) support ongoing short-study and paper review efforts in the N50; and (2) build content and scholarship in the form of books and papers on the relationship between maritime strategy and naval innovation. In the FY18 phase of the project, a team of NPS professors is producing a scholarly volume in partnership with King's College at the University of London on the topic: Maritime Strategy and Naval Innovation. 1. How can the Navy best structure itself to ensure that that its strategy development and implementation process can reflect changes in the dynamic strategic environment. 2. How can the Navy create a culture of innovation that ensures it has the human capital necessary to keep the organization head of its adversaries in the timeless adapt-react cycle that drives organizational and national behavior? 3. What are the issues in Eurasia that will define the maritime environment over the rest of the 21st century. How can the Navy anticipate these changes in its models for planning and force structure? 4. What are political dynamics facing the Navy and the nation in Eurasia that will define interactions on the high seas? Content preparation and analysis by a team of NPS faculty, to include James Russell, Jim Wirtz, Tom Young, Christopher Twomey and Donald Abenheim. The deliverable out of this project will be a book that can be used to educate future naval strategists like those in the NPS NSA 688 curriculum on Strategic Studies. The FY19 phase will see the same team produce a volume: The Struggle for Mastery in Eurasia.This project is a continuation of ongoing support by NPS to the work of N50 to further refining and improving the Navy's strategy development and implementation processes. This will be the fourth year of support to the N50. Under the auspices of this project, NPS faculty in the Department of National Security Affairs can: (1) support ongoing short-study and paper review efforts in the N50; and (2) build content and scholarship in the form of books and papers on the relationship between maritime strategy and naval innovation. In the FY18 phase of the project, a team of NPS professors is producing a scholarly volume in partnership with King's College at the University of London on the topic: Maritime Strategy and Naval Innovation. 1. How can the Navy best structure itself to ensure that that its strategy development and implementation process can reflect changes in the dynamic strategic environment. 2. How can the Navy create a culture of innovation that ensures it has the human capital necessary to keep the organization head of its adversaries in the timeless adapt-react cycle that drives organizational and national behavior? 3. What are the issues in Eurasia that will define the maritime environment over the rest of the 21st century. How can the Navy anticipate these changes in its models for planning and force structure? 4. What are political dynamics facing the Navy and the nation in Eurasia that will define interactions on the high seas? Content preparation and analysis by a team of NPS faculty, to include James Russell, Jim Wirtz, Tom Young, Christopher Twomey and Donald Abenheim. The deliverable out of this project will be a book that can be used to educate future naval strategists like those in the NPS NSA 688 curriculum on Strategic Studies. The FY19 phase will see the same team produce a volume: The Struggle for Mastery in Eurasia.This project is a continuation of ongoing support by NPS to the work of N50 to further refining and improving the Navy's strategy development and implementation processes. This will be the fourth year of support to the N50. Under the auspices of this project, NPS faculty in the Department of National Security Affairs can: (1) support ongoing short-study and paper review efforts in the N50; and (2) build content and scholarship in the form of books and papers on the relationship between maritime strategy and naval innovation. In the FY18 phase of the project, a team of NPS professors is producing a scholarly volume in partnership with King's College at the University of London on the topic: Maritime Strategy and Naval Innovation. 1. How can the Navy best structure itself to ensure that that its strategy development and implementation process can reflect changes in the dynamic strategic environment. 2. How can the Navy create a culture of innovation that ensures it has the human capital necessary to keep the organization head of its adversaries in the timeless adapt-react cycle that drives organizational and national behavior? 3. What are the issues in Eurasia that will define the maritime environment over the rest of the 21st century. How can the Navy anticipate these changes in its models for planning and force structure? 4. What are political dynamics facing the Navy and the nation in Eurasia that will define interactions on the high seas? Content preparation and analysis by a team of NPS faculty, to include James Russell, Jim Wirtz, Tom Young, Christopher Twomey and Donald Abenheim. The deliverable out of this project will be a book that can be used to educate future naval strategists like those in the NPS NSA 688 curriculum on Strategic Studies. The FY19 phase will see the same team produce a volume: The Struggle for Mastery in Eurasia.This project is a continuation of ongoing support by NPS to the work of N50 to further refining and improving the Navy's strategy development and implementation processes. This will be the fourth year of support to the N50. Under the auspices of this project, NPS faculty in the Department of National Security Affairs can: (1) support ongoing short-study and paper review efforts in the N50; and (2) build content and scholarship in the form of books and papers on the relationship between maritime strategy and naval innovation. In the FY18 phase of the project, a team of NPS professors is producing a scholarly volume in partnership with King's College at the University of London on the topic: Maritime Strategy and Naval Innovation. 1. How can the Navy best structure itself to ensure that that its strategy development and implementation process can reflect changes in the dynamic strategic environment. 2. How can the Navy create a culture of innovation that ensures it has the human capital necessary to keep the organization head of its adversaries in the timeless adapt-react cycle that drives organizational and national behavior? 3. What are the issues in Eurasia that will define the maritime environment over the rest of the 21st century. How can the Navy anticipate these changes in its models for planning and force structure? 4. What are political dynamics facing the Navy and the nation in Eurasia that will define interactions on the high seas? Content preparation and analysis by a team of NPS faculty, to include James Russell, Jim Wirtz, Tom Young, Christopher Twomey and Donald Abenheim. The deliverable out of this project will be a book that can be used to educate future naval strategists like those in the NPS NSA 688 curriculum on Strategic Studies. The FY19 phase will see the same team produce a volume: The Struggle for Mastery in Eurasia.This project is a continuation of ongoing support by NPS to the work of N50 to further refining and improving the Navy's strategy development and implementation processes. This will be the fourth year of support to the N50. Under the auspices of this project, NPS faculty in the Department of National Security Affairs can: (1) support ongoing short-study and paper review efforts in the N50; and (2) build content and scholarship in the form of books and papers on the relationship between maritime strategy and naval innovation. In the FY18 phase of the project, a team of NPS professors is producing a scholarly volume in partnership with King's College at the University of London on the topic: Maritime Strategy and Naval Innovation. 1. How can the Navy best structure itself to ensure that that its strategy development and implementation process can reflect changes in the dynamic strategic environment. 2. How can the Navy create a culture of innovation that ensures it has the human capital necessary to keep the organization head of its adversaries in the timeless adapt-react cycle that drives organizational and national behavior? 3. What are the issues in Eurasia that will define the maritime environment over the rest of the 21st century. How can the Navy anticipate these changes in its models for planning and force structure? 4. What are political dynamics facing the Navy and the nation in Eurasia that will define interactions on the high seas? Content preparation and analysis by a team of NPS faculty, to include James Russell, Jim Wirtz, Tom Young, Christopher Twomey and Donald Abenheim. The deliverable out of this project will be a book that can be used to educate future naval strategists like those in the NPS NSA 688 curriculum on Strategic Studies. The FY19 phase will see the same team produce a volume: The Struggle for Mastery in Eurasia.This project is a continuation of ongoing support by NPS to the work of N50 to further refining and improving the Navy's strategy development and implementation processes. This will be the fourth year of support to the N50. Under the auspices of this project, NPS faculty in the Department of National Security Affairs can: (1) support ongoing short-study and paper review efforts in the N50; and (2) build content and scholarship in the form of books and papers on the relationship between maritime strategy and naval innovation. In the FY18 phase of the project, a team of NPS professors is producing a scholarly volume in partnership with King's College at the University of London on the topic: Maritime Strategy and Naval Innovation. 1. How can the Navy best structure itself to ensure that that its strategy development and implementation process can reflect changes in the dynamic strategic environment. 2. How can the Navy create a culture of innovation that ensures it has the human capital necessary to keep the organization head of its adversaries in the timeless adapt-react cycle that drives organizational and national behavior? 3. What are the issues in Eurasia that will define the maritime environment over the rest of the 21st century. How can the Navy anticipate these changes in its models for planning and force structure? 4. What are political dynamics facing the Navy and the nation in Eurasia that will define interactions on the high seas? Content preparation and analysis by a team of NPS faculty, to include James Russell, Jim Wirtz, Tom Young, Christopher Twomey and Donald Abenheim. The deliverable out of this project will be a book that can be used to educate future naval strategists like those in the NPS NSA 688 curriculum on Strategic Studies. The FY19 phase will see the same team produce a volume: The Struggle for Mastery in Eurasia.N3/N5 - Information, Plans & StrategyThis research is supported by funding from the Naval Postgraduate School, Naval Research Program (PE 0605853N/2098). https://nps.edu/nrpChief of Naval Operations(CNO)Approved for public release; distribution is unlimited

Global Geopolitics [video]

A Seapower Conversation presentationNaval Warfare Studies Institute (NWSI

Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359

Number: 1 Publisher: Nature Publishing GroupThe potent and selective Gq protein inhibitor depsipeptide FR900359 (FR), originally discovered as the product of an uncultivable plant endosymbiont, is synthesized by a complex biosynthetic system comprising two nonribosomal peptide synthetase (NRPS) assembly lines. Here we characterize a cultivable bacterial FR producer, enabling detailed investigations into biosynthesis and attachment of the functionally important FR side chain. We reconstitute side chain assembly by the monomodular NRPS FrsA and the non-heme monooxygenase FrsH, and characterize intermolecular side chain transesterification to the final macrocyclic intermediate FR-Core, mediated by the FrsA thioesterase domain. We harness FrsA substrate promiscuity to generate FR analogs with altered side chains and demonstrate indispensability of the FR side chain for efficient Gq inhibition by comparative bioactivity, toxicity and docking studies. Finally, evolution of FR and side chain biosynthesis is discussed based on bioinformatics analyses. Side chain transesterification boosts potency and target affinity of selective Gq inhibitor natural products

Expression profiling of metabolic genes in response to methyl jasmonate reveals regulation of genes of primary and secondary sulfur-related pathways in Arabidopsis thaliana

The treatment of Arabidopsis thaliana with methyl jasmonate was used to investigate the reaction of 2467 selected genes of primary and secondary metabolism by macroarray hybridization. Hierarchical cluster analysis allowed distinctions to be made betwee