Begravningar i dagens Sverige - den personliga traditionen

The purpose of this essay is to study what people in Sweden today request regarding funerals. I want to investigate what people request and which of these requests can be met and which cannot. The material used are fifteen interviews I made with funeral officiants. Ten of those were with priests from The Church of Sweden, one with a vicar from the Catholic Church, one with a minister from a Serbian Orthodox Church, one with a reverend from the Missionary Church and two interviews were made with civil officiants. Further two interviews were made to clar-ify specific practical aspects regarding what needs to be done when, in the chain of events surrounding a death. These two interviews were made with the Chairman of the Swedish Fu-neral Association (SBF) and to a manager at a crematorium. The method used was qualitative interviews. The natures of the interviews were free with just some initial general questions and then I followed the informant in her or his story about what she or he noticed regarding requests when people have to plan a funeral. The theories used to analyze this material are: the theory of disembedment, - reflexivity, - fragmentation, - secularization, - religion privatized, - rational choice, - professionalization and finally the theory of ritual. The results and conclusions are that most of the requirements can be met, there are very few that cannot. Issues that were very frequently raised were those about the individual choices in the ceremony, such as music for instance. In general people expect the religious element in a funeral sometimes regardless whether it is a religious or a civil funeral

Siblings – Practical and Sensitive Relations

This book is about siblingship as a social and cultural phenomenon in contemporary Denmark. Being a sibling, having siblings and getting siblings are conditions in the lives of most children; actually 90 per cent of all children are registered as having siblings. Despite the prevalence, we have little knowledge of how children perceive being siblings, who they consider as siblings, and what they do or do not do together. Neither do we know much about how this phenomenon is culturally understood.Do children consider all the children they live with as siblings, even if they do not have parents in common?  Can you be more or less real siblings? Can you stop being siblings? Obviously, there are many ways of being a sibling, and sibling relations can change considerably as children grow up. New children may appear – in the shape of newborn babies or children from previous marriages – while other children may be separated by way of divorce or moving out. Sibling configurations vary, as do the experiences of having and getting siblings.The book is based on the research project “(Ex)Changeable Siblingships” conducted at the Danish School of Education, Aarhus University from 2011-2014 and financed by The Egmont Foundation. The project was based on empirical material collected throughout 2011 and 2012. It involved close to 100 children and their parents as well as selected professionals who work with children

”Authentic Microteaching” som akademisk lærings- og undervisningsmodel

Universitetsuddannelsen i idræt integrerer læring af praktiske kompetencer og akademisk faglig fordybelse. I denne artikel præsenterer vi ”authentic microtea-ching” som model, hvor medbestemmelse og formidlingsdimensionen indgår som centrale fokusområder i vores undervisning. Vores empiriske erfaringer med at ud-vikle modellen samt det lærings- og uddannelsesstrategiske sigte beskrives med udgangspunkt i et specifikt kursus, hvor vores studerende via små trefasede forløb bevæger sig fra at være deltagere i undervisning til selv at være formidlere af det faglige indhold i virkelighedsnære undervisningssituationer. I første fase introduce-res de studerende til praksisområdet i korte forløb tilrettelagt af universitetets un-dervisere, mens anden fase tager udgangspunkt i ”reciprocal peer teaching”, hvor de studerende underviser hinanden og udvikler deres egen praksis organiseret ud fra ”microteaching”-modellen. Tredje fase inkluderer korte undervisningsforløb med elever fra gymnasieskolen som deltagere i virkelighedsnære situationer ud fra ”au-tenthic pedagogy” og tilhørende refleksionspapirer (mini-underviser-portfolier) som parallel fordybelsesaktivitet

Comparative studies of TIMP-1 immunohistochemistry, TIMP-1 FISH analysis and plasma TIMP-1 in glioblastoma patients

Tissue inhibitor of metalloproteinases-1 (TIMP-1) has been associated with poor prognosis and resistance towards chemotherapy in several cancer forms. In a previous study we found an association between a low TIMP-1 tumor immunoreactivity and increased survival for glioblastoma patients, when compared to moderate and high TIMP-1 tumor immunoreactivity. The aim of the present study was to further evaluate TIMP-1 as a biomarker in gliomas by studying TIMP-1 gene copy numbers by fluorescence in situ hybridization (FISH) on 33 glioblastoma biopsies and by measuring levels of TIMP-1 in plasma obtained pre-operatively from 43 patients (31 gliomas including 21 glioblastomas) by enzyme-linked immunosorbent assay (ELISA). The results showed TIMP-1 gene copy numbers per cell ranging from 1 to 5 and the TIMP-1/CEN-X ratio ranging between 0.7 and 1.09, suggesting neither amplification nor loss of the TIMP-1 gene. The TIMP-1 protein levels measured in plasma were not significantly higher than TIMP-1 levels measured in healthy subjects. No correlation was identified between TIMP-1 tumor cell immunoreactivities and the TIMP-1 gene copy numbers or the plasma TIMP-1 levels. In conclusion, high immunohistochemical TIMP-1 protein levels in glioblastomas were not caused by TIMP-1 gene amplification and TIMP-1 in plasma was low and not directly related to tumor TIMP-1 immunoreactivity. The study suggests that TIMP-1 immunohistochemistry is the method of choice for future clinical studies evaluating TIMP-1 as a biomarker in glioblastomas. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s11060-016-2252-4) contains supplementary material, which is available to authorized users

Comparison of efficacy in patients with metastatic melanoma treated with ipilimumab and nivolumab who did or did not discontinue treatment due to immune-related adverse events:A real-world data study

SIMPLE SUMMARY: This retrospective study of real-world patients with metastatic melanoma shows that discontinuing treatment with combination immunotherapy due to adverse events does not result in a poorer outcome compared to patients that did not discontinue due to toxicity. This is important knowledge for clinicians and patients, as discontinuing treatment may cause great anxiety for patients because they believe that it may limit the response. ABSTRACT: Immune-related adverse events (irAEs) are very prevalent when treating patients with ipilimumab and nivolumab in combination, and 30–40% of patients discontinue the treatment for this reason. It is of high clinical relevance to investigate the consequences of discontinuing the treatment early since combination therapy with ipilimumab and nivolumab is the first line of treatment for many patients with metastatic melanoma. In this follow-up study, with real-world data from the nationwide DAMMED database, we investigated whether there was a difference in progression-free survival (PFS) and overall survival (OS) for patients who discontinued or did not discontinue treatment within the first four doses of treatment due to irAEs. In total, 448 patients were treated with ipilimumab and nivolumab. Of these, 133 patients discontinued due to irAEs in the induction phase. Using the Cox proportional hazards model, there was no significant difference in PFS when comparing the group that discontinued with the group that did not discontinue. The group that discontinued had a significantly longer OS than the group that received the full length of treatment. Therefore, we conclude that there is no significant negative impact on efficacy for patients who discontinue due to irAEs in the induction phase of combination immunotherapy for metastatic melanoma

Prediction of wastewater quality using amperometric bioelectronic tongues

Wastewater samples from a Swedish chemi-thermo-mechanical pulp (CTMP) mill collected at different purification stages in a wastewater treatment plant (WWTP) were analyzed with an amperometric enzyme-based biosensor array in a flow-injection system. In order to resolve the complex composition of the wastewater, the array consists of several sensing elements which yield a multidimensional response. We used principal component analysis (PCA) to decompose the array's responses, and found that wastewater with different degrees of pollution can be differentiated. With the help of partial least squares regression (PLS-R), we could link the sensor responses to the Microtox (R) toxicity parameter, as well as to global organic pollution parameters (COD, BOD, and TOC). From investigating the influences of individual sensors in the array, it was found that the best models were in most cases obtained when all sensors in the array were included in the PLS-R model. We find that fast simultaneous determination of several global environmental parameters characterizing wastewaters is possible with this kind of biosensor array, in particular because of the link between the sensor responses and the biological effect onto the ecosystem into which the wastewater would be released. In conjunction with multivariate data analysis tools, there is strong potential to reduce the total time until a result is yielded from days to a few minutes. (C) 2015 Elsevier B.V. All rights reserved