A Versatile tool? Applying the Cross-national Error Source Typology (CNEST) to triangulated pre-test data

There are certain error sources that are unique to cross-national questionnaires, or occur less frequently in single nation studies. Tools that help to identify these errors and separate them from measurement errors that only occur in single nation studies assist the cross-national survey researcher in producing a higher quality source questionnaire. In turn, this supports translators in producing functionally equivalent translations that work well in the target languages and cultures. The Cross-national Error Source Typology (CNEST) was developed as a tool for improving the effectiveness of cross-national questionnaire design and has already proved useful when applied to cognitive interview data. This paper assesses the consistency and versatility of the tool by applying it to triangulated cross-national pre-test data collected in Russia and the UK as part of the development of questions for the European Social Survey (ESS). The benefits and challenges of triangulating pre-test data in a cross-national setting are also highlighted and discussed

Searching For Evidence of Acculturation: Attitudes Toward Homosexuality Among Migrants Moving From Eastern to Western Europe

Attitudes toward gay men and lesbians are generally more tolerant in Western than in Eastern Europe. This study uses data from the first five rounds of the European Social Survey to examine acculturation among migrants moving from Eastern Europe to Western Europe, in terms of attitudes toward gay men and lesbians. After controlling for background factors associated with attitudes toward homosexuality, we find evidence of acculturation, whereby attitudes become more tolerant—and more typical of those prevalent in Western Europe—with longer residency in this region. This study builds on existing research into cross-national differences in attitudes toward homosexuality and extends the existing North American literature on acculturation to a European context

Characteristics of HIV-infected adolescents enrolled in a disclosure intervention trial in western Kenya

Knowledge of one's own HIV status is essential for long-term disease management, but there are few data on how disclosure of HIV status to infected children and adolescents in sub-Saharan Africa is associated with clinical and psychosocial health outcomes. We conducted a detailed baseline assessment of the disclosure status, medication adherence, HIV stigma, depression, emotional and behavioral difficulties, and quality of life among a cohort of Kenyan children enrolled in an intervention study to promote disclosure of HIV status. Among 285 caregiver-child dyads enrolled in the study, children's mean age was 12.3 years. Caregivers were more likely to report that the child knew his/her diagnosis (41%) compared to self-reported disclosure by children (31%). Caregivers of disclosed children reported significantly more positive views about disclosure compared to caregivers of non-disclosed children, who expressed fears of disclosure related to the child being too young to understand (75%), potential psychological trauma for the child (64%), and stigma and discrimination if the child told others (56%). Overall, the vast majority of children scored within normal ranges on screenings for behavioral and emotional difficulties, depression, and quality of life, and did not differ by whether or not the child knew his/her HIV status. A number of factors were associated with a child's knowledge of his/her HIV diagnosis in multivariate regression, including older age (OR 1.8, 95% CI 1.5-2.1), better WHO disease stage (OR 2.5, 95% CI 1.4-4.4), and fewer reported caregiver-level adherence barriers (OR 1.9, 95% CI 1.1-3.4). While a minority of children in this cohort knew their HIV status and caregivers reported significant barriers to disclosure including fears about negative emotional impacts, we found that disclosure was not associated with worse psychosocial outcomes

Elastomer-based touch sensor: Visualization of tactile pressure distribution

© Springer Nature Switzerland AG 2019. This paper presents an elastomer-based tactile sensor that can sense the tactile information in the form of pressure distribution. Our proposed sensor uses a piece of coated elastomer with thin conical pins underneath as the touch medium. The elastomer consists of 91 pins arranged in a honeycomb pattern, each pin can be regarded as a tactile sensing element. They are spaced at 1.5 mm in x and y direction. Each tactile element transfers the applied pressure value into a circular image pattern which can be captured by a camera placed at the end of the sensor structure. The applied pressure over the sensing array can be computed by processing the area of each sensing element. MATLAB is used to process the received images relating the applied pressure to the activated pixels in each circular pattern of the tactile element, and further visualizing the pressure distribution on a reconstructed surface of the sensor. This paper presents the development principle and fabrication process of the proposed sensor. The experimental results have proven the viability of the sensing concept; the prototype sensor can effectively detect single-point touch caused by objects with different dimensions and multi-point touch interactions with a spacing of more than 2.5 mm

Pharmacokinetics-based adherence measures for antiretroviral therapy in HIV-infected Kenyan children

BACKGROUND: Traditional medication adherence measures do not account for the pharmacokinetic (PK) properties of the drugs, potentially misrepresenting true therapeutic exposure. METHODS: In a population of HIV-infected Kenyan children on antiretroviral therapy including nevirapine (NVP), we used a one-compartment model with previously established PK parameters and Medication Event Monitoring Systems (MEMS®)-recorded dosing times to estimate the mean plasma concentration of NVP (Cp) in individual patients during 1 month of follow-up. Intended NVP concentration (Cp') was calculated under a perfectly followed dosing regimen and frequency. The ratio between the two (R = Cp/Cp') characterized the patient's NVP exposure as compared to intended level. Smaller R values indicated poorer adherence. We validated R by evaluating its association with MEMS®-defined adherence, CD4%, and spot-check NVP plasma concentrations assessed at 1 month. RESULTS: In data from 152 children (82 female), children were mean age 7.7 years (range 1.5-14.9) and on NVP an average of 2.2 years. Mean MEMS® adherence was 79%. The mean value of R was 1.11 (SD 0.37). R was positively associated with MEMS® adherence (p < 0.0001), and lower-than-median R values were significantly associated with lower NVP drug concentrations (p = 0.0018) and lower CD4% (p = 0.0178), confirming a smaller R value showed poorer adherence. CONCLUSION: The proposed adherence measures, R, captured patient drug-taking behaviours and PK properties

Prospective associations between internet use and poor mental health:A population-based study

ObjectivesMost of the evidence on the effects of internet use on mental health derives from cross-sectional research. We set out to explore prospective associations between internet use (hours online and specific internet experiences) and future mental health problems.MethodsParticipants were 1,431 respondents from the Avon Longitudinal Study of Parents and Children (ALSPAC), a UK birth cohort, who completed a questionnaire on internet use (time online and ten different internet experiences) when they were aged 18 years. Outcomes included past year self-harm, assessed at 21 years and high levels of depression and anxiety symptoms, assessed at 22 years. Associations were investigated using logistic regression models and analyses were conducted separately for males and females.ResultsFemales reporting high levels of internet use (number of hours online) were found to be at increased risk of depression at follow-up (highest tertile vs lowest tertile OR = 1.41, 95% CI 0.90 to 2.20), whereas males with high levels of internet use were at increased risk for self-harm (highest tertile vs lowest tertile OR = 2.53, 95%CI 0.93 to 6.90). There was no evidence to suggest an association between hours spent online and anxiety. With regards to the specific internet experiences, associations were found for females but not for males. In fully adjusted models, being bullied online (OR = 1.76, 95% CI 1.09 to 2.86) and meeting someone face to face (OR = 1.55, 95% CI 1.00 to 2.41) were associated with an increased risk of future depression. Being bullied online was also associated with an increased risk of future self-harm (OR = 2.42, 95% CI 1.41 to 4.15), along with receiving unwanted sexual comments or material, and coming across pornography and violent/gruesome material.ConclusionsOur findings highlight the importance of digital citizenship training to help teach young people to use technology safely and responsibly