5,947 research outputs found

    Enjoying God and Neighbor: Cultivating Desire for the Presence of the Other

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    The goal of this study is to explore the cultivation and diffusion of new habits of engagement with neighbors through experimental actions and the introduction of four bodily practices: Lectio Divina, daily prayer, weekly Eucharist, and inhabiting a third place. It is argued that the introduction of bodily practices within a praxis form of theological reflection can alter the habitual engagement of a church with its neighbors. The thesis was tested at Northside Baptist Church in Clinton, Mississippi. Through an examination of ecclesial formation, the study identifies desire as central to spiritual, congregational, and missional formation, and it argues that in order to cultivate or transform desire, a congregation needs new bodily practices coupled with receptive presence in their neighborhood. In order to test this hypothesis a missional action team was formed at Northside Baptist Church and led through an examination of their congregational praxis of neighborly engagement. The team took up the four bodily practices and met to explore neighborly engagement in light of Scripture and theological resources. The team was then led to create four short experiments of receptive engagement with neighbors and finally gathered back to reflect on their findings. The entire process was framed within the liturgical seasons from Epiphany to Pentecost. The study concludes that habits of paternalistic engagement can restrict the capacity of a church to recognize its neighbors as ends unto themselves to be enjoyed for their own sake and that congregational formation cannot be separated from receptive missional presence among neighbors. It commends an experiment aimed at neighborly presence. It recommends further work in spiritual formation through a process of Appreciative Inquiry, participation in a broad-based community organizing effort, and partnership with a neighboring church in its exploration of missional praxis. Content Reader: Alan Roxburgh, DMi

    Historical Biogeography of Velvet Ants (Hymenoptera: Mutillidae) in the North American Deserts and Arid Lands

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    Understanding the history of diversification in the North American deserts has long been a goal of biogeographers and evolutionary biologists. While it seems that a consensus is forming regarding the patterns of diversification in the Nearctic deserts in vertebrate taxa, little work has been done exploring the historical biogeography of widespread invertebrate taxa. Before a robust model of geobiotic change in the North American deserts can be proposed, it needs to be determined if the same historical events affected vertebrate and invertebrate taxa in the same way. I explored the phylogeographic patterns in four groups of widespread nocturnal velvet ants using two rDNA loci, the internal transcribed spacer regions 1 and 2 (ITS1 and ITS2). I used Bayesian phylogenetic analyses and haplotype network analyses to determine if a consistent geographic pattern exists among species and populations within each group. I also used molecular dating techniques to estimate divergence dates for each of the major phylogenetic clades. These analyses indicate that the species-level divergences in some groups occurred in the Neogene, and likely were driven by mountain building during Miocene-Pliocene times (~5 Ma) similar to the divergences in many vertebrate taxa, while species-level divergence in other groups occurred during the Pleistocene (1.8-0.1 Ma) and were likely driven by climatic oscillations and range contractions and expansion. Several recent studies have suggested that Neogene mountain-building events were more important to the development of a diverse desert-adapted biota. My research suggests, however, that both Neogene events and Pleistocene climatic changes were influential in the development of a species-rich nocturnal velvet ant fauna

    Promoting Critical Thinking In General Biology Courses: The Case Of The White Widow Spider

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    It is generally accepted that critical thinking is an important and, likely, essential, component of success in college and beyond. Despite the unanimity, only a low percentage of students in the U.S. can demonstrate critical thinking proficiency on standardized exams. This phenomenon may result from instructors using a reductionist view of critical thinking and focusing on learning processes rather than on evaluation of intellectual resources. In general biology courses, I use a non-threatening, active-learning, group activities to promote critical thinking. For example, students are presented with an email from a member of the community and asked to formulate a response using the internet as their resource. I have found that using this non-threatening activity near the start of the semester promotes students’ acquisition of critical thinking skills and allows me to present assignments focusing on more controversial topics that require critical thinking later in the semester

    Synthetic considerations in the self-assembly of coordination polymers of pyridine-functionalised hybrid Mn-Anderson polyoxometalates

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    The incorporation of polyoxometalates (POMs) as structural units into ordered porous constructs such as metal-organic frameworks (MOFs) is desirable for a range of applications where intrinsic properties inherited from both the MOF and POM are utilised, including catalysis and magnetic data storage. The controlled self-assembly of targeted MOF topologies containing POM units is hampered by the wide range of oxo and hydroxo units on the peripheries of POMs that can act as coordinating groups towards linking metal cations leading to a diverse range of structures, but incorporation of organic donor units into hybrid POMs offers an alternative methodology to programmably synthesise POM/MOF conjugates. Herein, we report six coordination polymers obtained serendipitously wherein Zn2+ and Cu2+ link pyridine-appended Mn-Anderson clusters into two- and three-dimensional network solids with complex connectivities and topologies. Careful inspection of their solid-state structures has allowed us to identify common structure-directing features across these coordination polymers, including a square motif where two Zn2+ cations bridge two POMs. By correlating certain structural motifs with synthetic conditions we have formulated a series of design considerations for the self-assembly of coordination polymers of hybrid POMs, encompassing the selection of reaction conditions, co-ligands and linking metal cations. We anticipate that these synthetic guidelines will inform the future assembly of hybrid POMs into functional MOF materials

    Analysis of Rocky Mountain snail (Oreohelix sp.) dietary preference

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    Rocky Mountain snails in the genus Oreohelix go mostly unnoticed beneath layers of leaf litter in the western Mountain ranges. These snails are most common in rocky foothill habitat that consists of high-density deciduous groves of maple and oak. It is in this habitat where a great number of unobserved feeding behaviors occur. While some research indicates that terrestrial snails may prefer to feed on living plants, it is thought that Oreohelix are detritivores, feeding primarily on decomposing plant matter. In this study we investigated Oreohelix diet by designing a food preference experiment. We provided two food sources (Boxelder maple leaf litter and fresh Romaine lettuce) to groups of 10 snails. Dietary preference was determined by collecting and examining fecal matter. Our results indicate that Oreohelix preferred leaf litter over fresh greens. This study provides an insight into the lesser-known ecology of Oreohelix snails and may aid in future conservation efforts as their habitat continues to be threatened by development

    Reducing Protected Lands in a Hotspot of Bee Biodiversity: Bees of Grand Staircase-Escalante National Monument

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    Grand Staircase-Escalante National Monument is a federally protected area found in central southern Utah. Designated in 1996 by President William J. Clinton, it was recently reduced in size by President Donald J. Trump in a proclamation that turned the one large monument into three smaller ones. A long-term, standardized study of the bees had been conducted from 2000–2003, revealing 660 species. The bee communities of the area are characterized by being spatially heterogeneous; most of the bees occur in isolated areas, with only a few being both abundant and widespread. Here we examine what affect the recent resizing of the monument has on the number, and ecology, of the bees now excluded from monument boundaries. Using the new monument boundaries and the geographic coordinates associated with each bee, we derived new species lists for each of the three monuments, and compared them to each other, and to the excluded lands. All three monuments now protect unique faunas, with Bray–Curtis similarity values not exceeding 0.59%. Each monument now harbors species not found in the other two monuments. We found that 84 bee species are no longer protected by any of the three monuments. These 84 species were not concentrated in one area that is now excluded, but were scattered throughout the newly excluded lands. For some of the excluded bee species, there is no evidence that they are rare or imperiled, being widespread throughout the west. However, there is a concentration of bees in the southern and eastern former monument lands that represent range extensions from nearby hot deserts. In addition to numerous range extensions, the list of excluded bees also contains several undescribed species (newly discovered species that have not yet been named and described by taxonomists) and morphospecies (individuals that are morphologically distinct, but that require additional research before species designations can be made). This indicates that the bee communities housed in these excluded areas would benefit from additional scientific inquiry. The areas now excluded from monument protections house a greater proportion of the original GSENM bee community than any of the three new monument units. We conclude this paper by discussing what the smaller monuments might mean for bee conservation in this hot spot of bee biodiversity and suggest that bee communities here and elsewhere should be taken into account when conservation decisions are being made

    Intraspeaker Comparisons of Acoustic and Articulatory Variability in American English /r/ Productions

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    The purpose of this report is to test the hypothesis that speakers utilize an acoustic, rather than articulatory, planning space for speech production. It has been well-documented that many speakers of American English use different tongue configurations to produce /r/ in different phonetic contexts. The acoustic planning hypothesis suggests that although the /r/ configuration varies widely in different contexts, the primary acoustic cue for /r/, a dip in the F3 trajectory, will be less variable due to tradeoffs in articulatory variability, or trading relations, that help maintain a relatively constant F3 trajectory across phonetic contexts. Acoustic data and EMMA articulatory data from seven speakers producing /r/ in different phonetic contexts were analyzed. Visual inspection of the EMMA data at the point of F3 minimum revealed that each speaker appeared to use at least two of three trading relation strategies that would be expected to reduce F3 variability. Articulatory covariance measures confirmed that all seven speakers utilized a trading relation between tongue back height and tongue back horizontal position, six speakers utilized a trading relation between tongue tip height and tongue back height, and the speaker who did not use this latter strategy instead utilized a trading relation between tongue tip height and tongue back horizontal position. Estimates of F3 variability with and without the articulatory covariances indicated that F3 would be much higher for all speakers if the articulatory covariances were not utilized. These conclusions were further supported by a comparison of measured F3 variability to F3 variabilities estimated from the pellet data with and without articulatory covariances. In all subjects, the actual F3 variance was significantly lower than the F3 variance estimated without articulatory covariances, further supporting the conclusion that the articulatory trading relations were being used to reduce F3 variability. Together, these results strongly suggest that the neural control mechanisms underlying speech production make elegant use of trading relations between articulators to maintain a relatively invariant acoustic trace for /r/ across phonetic contexts

    Anti-CD20 therapy depletes activated myelin-specific CD8+ T cells in multiple sclerosis.

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    CD8+ T cells are believed to play an important role in multiple sclerosis (MS), yet their role in MS pathogenesis remains poorly defined. Although myelin proteins are considered potential autoantigenic targets, prior studies of myelin-reactive CD8+ T cells in MS have relied on in vitro stimulation, thereby limiting accurate measurement of their ex vivo precursor frequencies and phenotypes. Peptide:MHC I tetramers were used to identify and validate 5 myelin CD8+ T cell epitopes, including 2 newly described determinants in humans. The validated tetramers were used to measure the ex vivo precursor frequencies and phenotypes of myelin-specific CD8+ T cells in the peripheral blood of untreated MS patients and HLA allele-matched healthy controls. In parallel, CD8+ T cell responses against immunodominant influenza epitopes were also measured. There were no differences in ex vivo frequencies of tetramer-positive myelin-specific CD8+ T cells between MS patients and control subjects. An increased proportion of myelin-specific CD8+ T cells in MS patients exhibited a memory phenotype and expressed CD20 compared to control subjects, while there were no phenotypic differences observed among influenza-specific CD8+ T cells. Longitudinal assessments were also measured in a subset of MS patients subsequently treated with anti-CD20 monoclonal antibody therapy. The proportion of memory and CD20+ CD8+ T cells specific for certain myelin but not influenza epitopes was significantly reduced following anti-CD20 treatment. This study, representing a characterization of unmanipulated myelin-reactive CD8+ T cells in MS, indicates these cells may be attractive targets in MS therapy
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