2,477 research outputs found
Financial Statement Outcomes When Alternative Derivative Hedging Designations Exist
When alternate reporting methods exist, financial statement preparers tend to select methods that provide more favorable results. Certain hedging transactions may be designated as either a fair value hedge or a cash flow hedge. Both designations achieve the objective of matching the gain <loss> on the derivative with the loss <gain> on the hedged item in the same reporting period. However, the cash flow hedge accounting tends to create a greater appearance of equity volatility. 
An Audible Demonstration Of The Speed Of Sound In Bubbly Liquids
The speed of sound in a bubbly liquid is strongly dependent upon the volume fraction of the gas phase, the bubble size distribution, and the frequency of the acoustic excitation. At sufficiently low frequencies, the speed of sound depends primarily on the gas volume fraction. This effect can be audibly demonstrated using a one-dimensional acoustic waveguide, in which the flow rate of air bubbles injected into a water-filled tube is varied by the user. The normal modes of the waveguide are excited by the sound of the bubbles being injected into the tube. As the flow rate is varied, the speed of sound varies as well, and hence, the resonance frequencies shift. This can be clearly heard through the use of an amplified hydrophone and the user can create aesthetically pleasing and even musical sounds. In addition, the apparatus can be used to verify a simple mathematical model known as Wood's equation that relates the speed of sound of a bubbly liquid to its void fraction. (c) 2008 American Association of Physics Teachers.Mechanical Engineerin
Diaphus taaningi Norman, the principal component of a shallow sound-scattering layer in the Cariaco Trench, Venezuela
A myctophid fish, Diaphus taaningi Norman, is the principal component of a distinct daytime sound-scattering layer lying near 250 m, well above the anoxic, hydrogen-sulfide zone of the Cariaco Trench. The scattering layer produced strong sonar echoes at 12, 25, and 50 kHz; mean sound-scattering strength at layer depth at 25 kHz was approximately --73 dB and at 50 kHz was approximately --67 dB...
The influence of self-efficacy and outcome expectations on the relationship between perceived environment and physical activity in the workplace
BACKGROUND: Recent research and commentary contends that ecological approaches may be particularly useful for understanding and promoting physical activity participation in various settings including the workplace. Yet within the physical activity domain there is a lack of understanding of how ecological environment factors influence behaviour. Thus, the purpose of this study was to examine the relationships between perceived environment, social-cognitive variables, and physical activity behaviour. METHODS: Participants (N = 897) were employees from three large worksites who completed self-report inventories containing measures of self-efficacy, outcome expectations, perceptions of the workplace environment (PWES), and physical activity behaviour during both leisure-time and incorporated throughout the workday. RESULTS: Results of both bivariate and multiple regression analyses indicated the global PWES scores had a limited association with leisure-time physical activity (R(2)adj =.01). Sequential regression analyses supported a weak association between physical activity incorporated in the workplace and PWES (R(2)adj = .04) and the partial mediation of self-efficacy on the relationship between PWES and workplace physical activity (variance accounted for reduced to R(2)adj = .02 when self-efficacy was controlled). CONCLUSION: Overall, the results of the present investigation indicate that self-efficacy acted as a partial mediator of the relationship between perceived environment and workplace physical activity participation. Implications of the findings for physical activity promotion using ecological-based approaches, and future directions for research from this perspective in worksite settings are discussed
Impulsive, Disinhibited Behavior—Dining in a Restaurant
Dining in a restaurant with a loved one who has dementia can be an ordeal, especially if the expectations of the caregiver do not match those of the patient and the restaurant environment is not suitable for patients with dementia. The size of the dining area, lighting, background music or noise, décor of the room, number of customers, variety of the items on the menu, number of plates and cutlery on the table, in addition to flowers, candles, and other decorations on the table are all potent distractors. There are so many stimuli; the patient can be overwhelmed with information overload and not able to focus on the main purpose of the event: have dinner and especially enjoy the other person’s company. In this case scenario, we present a 62-year-old man diagnosed with behavioral variant frontotemporal dementia (bvFTD). His daughter “invited” him to have dinner with her at a very fancy restaurant to celebrate her promotion at work. Unfortunately, whereas the evening started very well, it had a catastrophic ending. We discuss what went wrong in the patient/daughter interaction and how the catastrophic ending could have been avoided or averted
The eukaryotic initiation factor 2 kinase GCN2 protects against hepatotoxicity during asparaginase treatment
Asparaginase is an important drug in the treatment regimen for acute lymphoblastic leukemia. Asparaginase depletes circulating asparagine and glutamine, activating an amino acid stress response (AAR) involving phosphorylation of eukaryotic initiation factor 2 (eIF2) by general control nonderepressible kinase 2 (GCN2). We hypothesized that GCN2 functions to mitigate hepatic stress during asparaginase therapy by activating the AAR. To test this idea, C57BL/6J wild-type mice (Gcn2(+/+)) and those deleted for Gcn2 (Gcn2(-/-)) were injected with asparaginase or saline excipient one time daily for 1 or 6 days. In liver, increased phosphorylation of eIF2 and mRNA expression of AAR target genes activating transcription factor 4, asparagine synthetase, eIF4E-binding protein 1, and CAAT enhancer-binding protein homologous protein were significantly blunted or blocked in the liver of Gcn2(-/-) mice. Loss of AAR during asparaginase coincided with increases in mammalian target of rapamycin signaling, hepatic triglyceride accumulation, and DNA damage in association with genetic markers of oxidative stress (glutathione peroxidase) and inflammation (tumor necrosis factor alpha-α). Although asparaginase depleted circulating asparagine in both Gcn2(+/+) and Gcn2(-/-) mice, all other amino acids, including plasma glutamine, were elevated in the plasma of Gcn2(-/-) mice. This study shows that loss of GCN2 promotes oxidative stress and inflammatory-mediated DNA damage during asparaginase therapy, suggesting that patients with reduced or dysfunctional AAR may be at risk of developing hepatic complications during asparaginase treatment
Insomnia and Mild Cognitive Impairment
Insomnia is a common problem in older people, especially in patients with mild cognitive impairment (MCI) whose circadian rhythm is often compromised. Insomnia exerts such a toll on caregivers that it is frequently the primary reason for seeking to institutionalize their loved ones. Three different types of insomnia are recognized: sleep-onset or initial insomnia, sleep maintenance or middle insomnia, and early morning awakening or late insomnia. Nocturnal hypoglycemia, as a cause of middle insomnia, is the main focus of this case study. Other types of insomnia are also briefly reviewed. The management of insomnia is then discussed including sleep hygiene, the usefulness and potential drawbacks of dietary supplements, nonprescription over-the-counter preparations and prescription hypnotics. Sleep architecture is then briefly reviewed, emphasizing the importance of its integrity and the role of each sleep stage
Driving and Patients With Dementia
Driving is a symbol of autonomy and independence, eagerly awaited during adolescence, cherished during adulthood and reluctantly rescinded during old age. It is nevertheless an individual’s privilege, not right, especially as driving may affect other drivers and pedestrians on the road. It is therefore not only the individual patient who is at stake but essentially the entire community. In this case scenario, we describe the situation that arose when a patient with multi-infarct dementia wanted to go for a drive and his son and grandson tried to convince him that he could no longer drive. What went wrong in the caregivers/patient interaction is presented. The futility of arguing with patients who have dementia is highlighted as well as the suspiciousness it may generate. Alternate actions that can be useful to avoid/avert the situation from escalating and having a catastrophic ending are discussed. Testing/evaluating patients with dementia for fitness to drive is also reviewed and a list of select resources is included
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