1,149 research outputs found

    Nature of Sonoluminescence: Noble Gas Radiation Excited by Hot Electrons in "Cold" Water

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    We show that strong electric fields occurring in water near the surface of collapsing gas bubbles because of the flexoelectric effect can provoke dynamic electric breakdown in a micron-size region near the bubble and consider the scenario of the SBSL. The scenario is: (i) at the last stage of incomplete collapse of the bubble the gradient of pressure in water near the bubble surface has such a value and sign that the electric field arising from the flexoelectric effect exceeds the threshold field of the dynamic electrical breakdown of water and is directed to the bubble center; (ii) mobile electrons are generated because of thermal ionization of water molecules near the bubble surface; (iii) these electrons are accelerated in ''cold'' water by the strong electric fields; (iv) these hot electrons transfer noble gas atoms dissolved in water to high-energy excited states and optical transitions between these states produce SBSL UV flashes in the trasparency window of water; (v) the breakdown can be repeated several times and the power and duration of the UV flash are determined by the multiplicity of the breakdowns. The SBSL spectrum is found to resemble a black-body spectrum where temperature is given by the effective temperature of the hot electrons. The pulse energy and some other characteristics of the SBSL are found to be in agreement with the experimental data when realistic estimations are made.Comment: 11 pages (RevTex), 1 figure (.ps

    Knockdown of the schizophrenia susceptibility gene TCF4 alters gene expression and proliferation of progenitor cells from the developing human neocortex

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    BACKGROUND: Common variants in the TCF4 gene are among the most robustly supported genetic risk factors for schizophrenia. Rare TCF4 deletions and loss-of-function point mutations cause Pitt-Hopkins syndrome, a developmental disorder associated with severe intellectual disability. METHODS: To explore molecular and cellular mechanisms by which TCF4 perturbation could interfere with human cortical development, we experimentally reduced the endogenous expression of TCF4 in a neural progenitor cell line derived from the developing human cerebral cortex using RNA interference. Effects on genome-wide gene expression were assessed by microarray, followed by Gene Ontology and pathway analysis of differentially expressed genes. We tested for genetic association between the set of differentially expressed genes and schizophrenia using genome-wide association study data from the Psychiatric Genomics Consortium and competitive gene set analysis (MAGMA). Effects on cell proliferation were assessed using high content imaging. RESULTS: Genes that were differentially expressed following TCF4 knockdown were highly enriched for involvement in the cell cycle. There was a nonsignificant trend for genetic association between the differentially expressed gene set and schizophrenia. Consistent with the gene expression data, TCF4 knockdown was associated with reduced proliferation of cortical progenitor cells in vitro. LIMITATIONS: A detailed mechanistic explanation of how TCF4 knockdown alters human neural progenitor cell proliferation is not provided by this study. CONCLUSION: Our data indicate effects of TCF4 perturbation on human cortical progenitor cell proliferation, a process that could contribute to cognitive deficits in individuals with Pitt-Hopkins Syndrome and risk for schizophrenia

    On the nature of the z=0 X-ray absorbers: I. Clues from an external group

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    Absorption lines of OVII at redshift zero are observed in high quality Chandra spectra of extragalactic sightlines. The location of the absorber producing these lines, whether from the corona of the Galaxy or from the Local Group or even larger scale structure, has been a matter of debate. Here we study another poor group like our Local Group to understand the distribution of column density from galaxy to group scales. We show that we cannot yet rule out the group origin of z=0 systems. We further argue that the debate over Galactic vs. extragalactic origin of z=0 systems is premature as they likely contain both components and predict that future higher resolution observations will resolve the z=0 systems into multiple components.Comment: Submitted to ApJ

    Persistent currents in a circular array of Bose-Einstein condensates

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    A ring-shaped array of Bose-Einstein condensed atomic gases can display circular currents if the relative phase of neighboring condensates becomes locked to certain values. It is shown that, irrespective of the mechanism responsible for generating these states, only a restricted set of currents are stable, depending on the number of condensates, on the interaction and tunneling energies, and on the total number of particles. Different instabilities due to quasiparticle excitations are characterized and possible experimental setups for testing the stability prediction are also discussed.Comment: 7 pages, REVTex

    Entangled quantum tunneling of two-component Bose-Einstein condensates

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    We examine the quantum tunneling process in Bose condensates of two interacting species trapped in a double well configuration. We discover the condition under which particles of different species can tunnel as pairs through the potential barrier between two wells in opposition directions. This novel form of tunneling is due to the interspecies interaction that eliminates the self- trapping effect. The correlated motion of tunneling atoms leads to the generation of quantum entanglement between two macroscopically coherent systems.Comment: 4 pages, 3 figure

    Dietary lecithin improves the healthiness of pork

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    Dietary lecithin may provide health benefits to pork as well as improving its eating quality by reducing chewiness and hardness (D'Souza et al.., 2005). Human studies have shown lecithin supplementation can reduce cholesterol significantly (Spilburg et al., 2003) and we hypothesised that lecithin supplementation would have a similar effect in pigs. The use of lecithin supplementation to improve the 'healthiness' of pork or pork products, while also improving the tenderness of pork, could provide the pork industry with significant marketing opportunities. The aim of this experiment was to investigate the effect of lecithin supplementation on the fatty acid profile of pork and also on the plasma cholesterol of pigs

    Multiwavelength Study of M8.9/3B Solar Flare from AR NOAA 10960

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    We present a multi-wavelength analysis of a long duration white-light solar flare (M8.9/3B) event that occurred on 4 June 2007 from NOAA AR 10960. The flare was observed by several spaceborne instruments, namely SOHO/MDI, Hinode/SOT, TRACE and STEREO/SECCHI. The flare was initiated near a small, positive-polarity, satellite sunspot at the centre of the AR, surrounded by opposite-polarity field regions. MDI images of the AR show considerable amount of changes in a small positive-polarity sunspot of delta configuration during the flare event. SOT/G-band (4305 A) images of the sunspot also suggest the rapid evolution of the positive-polarity sunspot with highly twisted penumbral filaments before the flare event, which were oriented in the counterclockwise direction. It shows the change in orientation and also remarkable disappearance of twisted penumbral filaments (~35-40%) and enhancement in umbral area (~45-50%) during the decay phase of the flare. TRACE and SECCHI observations reveal the successive activations of two helical twisted structures associated with this sunspot, and the corresponding brightening in the chromosphere as observed by the time-sequence images of SOT/Ca II H line (3968 A). The secondary-helical twisted structure is found to be associated with the M8.9 flare event. The brightening starts 6-7 min prior to the flare maximum with the appearance of secondary helical-twisted structure. The flare intensity maximizes as this structure moves away from the AR. This twisted flux-tube associated with the flare triggering, is found to be failed in eruption. The location of the flare is found to coincide with the activation site of the helical twisted structures. We conclude that the activations of successive helical twists in the magnetic flux tubes/ropes plays a crucial role in the energy build-up process and triggering of M-class solar flare without a CME.Comment: 22 pages, 12 figures, Accepted for Publication in Solar Physic

    A Planck-scale axion and SU(2) Yang-Mills dynamics: Present acceleration and the fate of the photon

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    From the time of CMB decoupling onwards we investigate cosmological evolution subject to a strongly interacting SU(2) gauge theory of Yang-Mills scale Λ104\Lambda\sim 10^{-4} eV (masquerading as the U(1)YU(1)_{Y} factor of the SM at present). The viability of this postulate is discussed in view of cosmological and (astro)particle physics bounds. The gauge theory is coupled to a spatially homogeneous and ultra-light (Planck-scale) axion field. As first pointed out by Frieman et al., such an axion is a viable candidate for quintessence, i.e. dynamical dark energy, being associated with today's cosmological acceleration. A prediction of an upper limit Δtmγ=0\Delta t_{m_\gamma=0} for the duration of the epoch stretching from the present to the point where the photon starts to be Meissner massive is obtained: Δtmγ=02.2\Delta t_{m_\gamma=0}\sim 2.2 billion years.Comment: v3: consequences of an error in evolution equation for coupling rectified, only a minimal change in physics results, two refs. adde

    Macroscopic Quantum Fluctuations in the Josephson Dynamics of Two Weakly Linked Bose-Einstein Condensates

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    We study the quantum corrections to the Gross-Pitaevskii equation for two weakly linked Bose-Einstein condensates. The goals are: 1) to investigate dynamical regimes at the borderline between the classical and quantum behaviour of the bosonic field; 2) to search for new macroscopic quantum coherence phenomena not observable with other superfluid/superconducting systems. Quantum fluctuations renormalize the classical Josephson oscillation frequencies. Large amplitude phase oscillations are modulated, exhibiting collapses and revivals. We describe a new inter-well oscillation mode, with a vanishing (ensemble averaged) mean value of the observables, but with oscillating mean square fluctuations. Increasing the number of condensate atoms, we recover the classical Gross-Pitaevskii (Josephson) dynamics, without invoking the symmetry-breaking of the Gauge invariance.Comment: Submitte
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