Defending Hermeneutics

This article offers several perspectives on the challenges of defending Gadamerian hermeneutics in applied research settings, specifically counselling psychology and nursing. Given the lack of methodological steps associated with the method, researchers employing hermeneutics can be vulnerable to scrutiny from others. We discuss the uncertainty that is inevitable when embarking on hermeneutic inquiry and provide personal accounts of how we have encountered the uncertain nature of hermeneutics

Disclosing an Eating Disorder: A Situational Analysis of Online Accounts

Disclosing a mental illness can be difficult, especially for those affected by eating disorders. Individuals impacted by eating disorders often worry that disclosing their situation may lead to fear, judgment, and stigmatization. Online eating disorder communities have become increasingly popular, hosting thousands of users worldwide, and may be safe places for individuals with eating disorders to communicate and connect. In this postmodern study, we utilized situational analysis to examine online accounts on publically accessible websites where individuals discussed disclosing eating disorders. Situational Analysis utilizes illustrative mapping techniques to demonstrate the complexity of the situation of inquiry, allowing researchers to highlight heterogeneities. Our findings demonstrated (a) the fight that frequently occurs after an eating disorder disclosure, (b) the notion that eating disorders are a monstrous issue, and (c) stigmatization one experiences after disclosing and when considering to disclose. This study has potential to inform educational recommendations given to the public about disclosures and stigma in regard to eating disorders, as well as earlier identification and treatment outcomes for individuals with eating disorders

Effects of Smoking vs. Nicotine Replacement Therapy During Pregnancy on Childhood Health Outcomes: An Integrative Literature Review

PICOT: In pregnant women does the use of nicotine replacement therapy compared to smoking during pregnancy reduce the risk of future childhood health concerns? Methods: A search was conducted on healthcare literature databases (Alt HealthWatch, AMED, CINAHL, and Medline).The initial search yielded 940 results related to the topic. Initial review narrowed the search to 25 articles. Articles were excluded if published before 2008. After reviewing the full articles and evaluating effectiveness of the studies, 12 studies met the criteria. These 12 articles focused on the effects of smoking and childhood outcomes, NRT, and success of NRT. Findings: The articles concluded that NRT may aid in positive health outcomes since it excludes the risk factors associated with carbon monoxide and other carcinogens found in cigarettes. The NRT still delivers significant levels of nicotine exposure to the fetus and leads to pregnancy complications ending in low birth weight and preterm birth. Recommendations: Further studies should be conducted on the effects of nicotine and NRT especially on birth outcomes and future childhood health concerns

Not Quite this and not Quite that: Anorexia Nervosa, Counselling Psychology, and Hermeneutic Inquiry in a Tapestry of Ambiguity

As a group of researchers exploring how to best understand the complex topic of families discovering their loved one has anorexia nervosa (AN), we found that we had to weave ambiguity into our design. Embracing ambiguity allowed us to create a tapestry that acknowledges the ambiguity of AN, counselling psychology (and other helping professions), and hermeneutic inquiry. In fact, the “not quite this and not quite that” features of these three constructs emerged as the thread that holds the inquiry together. We review the topic of AN through a lens of ambiguity.  Further, we position both the field of counselling psychology and the research method of hermeneutic inquiry as compatible frameworks in the study of AN, in both practice and research. By acknowledging, and at times even embracing, ambiguity, we respect the complexity of the situation we are studying. 

Physiological and Growth Responses of Midrotation Loblolly Pine to Treatments of Fire, Herbicide, and Fertilizer

The objectives of this study were to examine the effects of fertilizer and understory vegetation control (herbicide and prescribed fire) on mature tree physiology and to link observed physiological responses with tree growth. Photosynthetic rate (photosynthesis), transpiration, stomatal conductance, stem diameter, and crown area were measured in two midrotation loblolly pine plantations in East Texas. Rates of photosynthesis, E and gs for the midsummer measurements were significantly reduced by fertilizer treatments on both sites. Drought in east Texas during the last 3 years may have influenced this result. Trees receiving fire at the site with a comparatively more dense live pre-treatment understory exhibited higher rates of photosynthesis; however, prescribed fire had no positive effect on growth. Herbicide treatment significantly increased the change in diameter growth of unfertilized trees at both sites between 1999-2001 by an average of 5 percent, but had no effect on growth of fertilized trees. Increase in diameter growth per unit crown area was significantly greater in unfertilized trees receiving herbicide than in controls

Promoter de-methylation of cyclin D2 by sulforaphane in prostate cancer cells

Sulforaphane (SFN), an isothiocyanate derived from cruciferous vegetables, induces potent anti-proliferative effects in prostate cancer cells. One mechanism that may contribute to the anti-proliferative effects of SFN is the modulation of epigenetic marks, such as inhibition of histone deacetylase (HDAC) enzymes. However, the effects of SFN on other common epigenetic marks such as DNA methylation are understudied. Promoter hyper-methylation of cyclin D2, a major regulator of cell cycle, is correlated with prostate cancer progression, and restoration of cyclin D2 expression exerts anti-proliferative effects on LnCap prostate cancer cells. Our study aimed to investigate the effects of SFN on DNA methylation status of cyclin D2 promoter, and how alteration in promoter methylation impacts cyclin D2 gene expression in LnCap cells. We found that SFN significantly decreased the expression of DNA methyltransferases (DNMTs), especially DNMT1 and DNMT3b. Furthermore, SFN significantly decreased methylation in cyclin D2 promoter regions containing c-Myc and multiple Sp1 binding sites. Reduced methlyation of cyclin D2 promoter corresponded to an increase in cyclin D2 transcript levels, suggesting that SFN may de-repress methylation-silenced cyclin D2 by impacting epigenetic pathways. Our results demonstrated the ability of SFN to epigenetically modulate cyclin D2 expression, and provide novel insights into the mechanisms by which SFN may regulate gene expression as a prostate cancer chemopreventive agent

Electronic band structure and carrier effective mass in calcium aluminates

First-principles electronic band structure investigations of five compounds of the CaO-Al2O3 family, 3CaO.Al2O3, 12CaO.7Al2O3, CaO.Al2O3, CaO.2Al2O3 and CaO.6Al2O3, as well as CaO and alpha-, theta- and kappa-Al2O3 are performed. We find that the conduction band in the complex oxides is formed from the oxygen antibonding p-states and, although the band gap in Al2O3 is almost twice larger than in CaO, the s-states of both cations. Such a hybrid nature of the conduction band leads to isotropic electron effective masses which are nearly the same for all compounds investigated. This insensitivity of the effective mass to variations in the composition and structure suggests that upon a proper degenerate doping, both amorphous and crystalline phases of the materials will possess mobile extra electrons

Impact of historical land‐use changes on greenhouse gas exchange in the U.S. Great Plains, 1883–2003

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/117205/1/eap20112141105.pd