Quartet: Dissecting a Story

From the beginning of my investigation of Quartet, the text has intimidated me; after all, the script is infused with a multitude of literary, historical, and philosophical references and quotes all of which Heiner Mueller, himself, prefers to dissociate himself from. The theatre has nothing to do with ideas, Mueller once stated. Paradoxically his theatre is one that is full of ideas and whether Mueller chose, in his own lifetime, to recognize the ideas of his theatre or not, it is precisely his provocative ideas and images that has been the basis for this paper. In his dramatic text, Quartet, Heiner Mueller negotiates an array of theatrical theories and aesthetics, philosophies, segments of history, literary personas, in addition to a powerful selection of images, thus generating a stimulating multi-faceted dramatic collage

Olefin strain energy as a predictor of isolability

Data collection contains:Determination of the olefin stratin energy ranges corresponding to isolable, observable and unstable alkenes with contemporary forcefields - Bridgehead alkenes used to determine the olefin strain energy ranges corresponding to isolable, observable, and unstable  alkenes;Forcefield energies of alkenes S1-S25 and alkanes S1H2-S25H2;Olefin strain energies of alkenes S1-S25;Olefin strain energies of alkenes S1-S25 computed with different forcefields;Olefin strain energies of alkenes S1-S19 computed with different force fields, plotted against MM1 OS energy;Olefin strain energy calculations for natural products -Forcefield energies or bridgehead alkene natural products or putative bridgehead alkene natural products, and the  corresponding alkanes;Olefin strain energies of bridgehead alkene natural products or putative alkene natural products;OPLS_2005 Optimized geometries;Density Functional Theory (DFT) calculations -DFT calculations on NP's giving a measure of the amount of strain energy not captured by the forcefield;B3LYP-D3 optimized geometries and associated energies;A small set of alkenes for rapid estimation of OS cutoffs for other forcefield

A Typical Drunkard: The Establishment of the Alcoholic Stereotype on the American Stage

America saw much of the drunkard on stage during the nineteenth century, and our perceptions about who he was, what drove his actions, and what the inevitable consequences of his drinking would be, were well established in the American imagination by the turn of the century. Thus, it was during these years, and through depictions in melodramatic temperance plays that the characterization of the stereotypical American drunkard came to live in our collective psyche. The typical alcoholic, inevitably male, had failing ethics and morals, and was a victim of his own weak will. This project examines how the development of an ideological and religious view of excessive drinking, and the staging of that view, codified the characteristics of alcoholism through examinations of the alcoholic character, the alcoholism narrative and the ideological messages about alcoholism as depicted in seven plays produced between 1844 and 1888. Patterns found in staged depictions placed in the American consciousness an image of the alcoholic that continues to shape public understanding of excessive drinking. This project defines and examines the components of that stereotype through the examination of representative plays taken from popular temperance drama, professional theater, and amateur plays performed in small towns and large cities across the country

Marshall University Music Department Presents the Marshall University Symphony Orchestra, Concert of Soloists. Dr. Elizabeth Reed Smith, conductor, with, William H. Holderby II, horn, Brianna Williams, euphonium, Mary Beth Withers, soprano

https://mds.marshall.edu/music_perf/1446/thumbnail.jp

CHEMISTRY DISCIPLINE MEETING

The tertiary sector has been rocked to its core by the COVID-19 pandemic and the subsequent shift to online teaching. One of the areas most impacted has been how we assess our students and the associated challenges relating to academic integrity, quality, and logistics. The 2021 ACSME Chemistry Discipline Day workshop will focus on these challenges and aims to crowdsource ideas for solutions at both an individual and institutional level. This conversation is an extension of a recent workshop at the RACI Chemistry Education Division Symposium and outcomes from this workshop will inform discussions held by our representatives with the Australian Council of Deans of Science (ACDS)

Friends, colleagues, authors, lend us your data

The JCB was founded by a group of scientists who needed a journal to showcase their micrographs with the highest quality reproduction. Our commitment to innovative presentation and sharing of image data continues today with the JCB DataViewer

Signs of a vector's adaptive choice: on the evasion of infectious hosts and parasite-induced mortality

Laboratory and field experiments have demonstrated in many cases that malaria vectors do not feed randomly, but show important preferences either for infected or non-infected hosts. These preferences are likely in part shaped by the costs imposed by the parasites on both their vertebrate and dipteran hosts. However, the effect of changes in vector behaviour on actual parasite transmission remains a debated issue. We used the natural associations between a malaria-like parasite Polychromophilus murinus, the bat fly Nycteribia kolenatii and a vertebrate host the Daubenton's bat Myotis daubentonii to test the vector's feeding preference based on the host's infection status using two different approaches: 1) controlled behavioural assays in the laboratory where bat flies could choose between a pair of hosts; 2) natural bat fly abundance data from wild-caught bats, serving as an approximation of realised feeding preference of the bat flies. Hosts with the fewest infectious stages of the parasite were most attractive to the bat flies that did switch in the behavioural assay. In line with the hypothesis of costs imposed by parasites on their vectors, bat flies carrying parasites had higher mortality. However, in wild populations, bat flies were found feeding more based on the bat's body condition, rather than its infection level. Though the absolute frequency of host switches performed by the bat flies during the assays was low, in the context of potential parasite transmission they were extremely high. The decreased survival of infected bat flies suggests that the preference for less infected hosts is an adaptive trait. Nonetheless, other ecological processes ultimately determine the vector's biting rate and thus transmission. Inherent vector preferences therefore play only a marginal role in parasite transmission in the field. The ecological processes rather than preferences per se need to be identified for successful epidemiological predictions

Investigative approaches: Lessons learned from the RaDonda Vaught case

Accidental patient harms occur frequently in healthcare, but their exact prevalence and interventions that will best prevent them are still poorly understood. In rare cases, healthcare providers who have contributed to accidental patient harm may be criminally prosecuted to obtain justice for the patient and family or to set an example, which theoretically prevents other providers from making similar mistakes due to fear of punishment. A recent case where this strategy was chosen is the RaDonda L. Vaught vs. Tennessee (2022) criminal case. The present article discusses this case and its ramifications, as well as provides concrete recommendations for actions that healthcare organizations should take to foster a safer and more resilient healthcare system. Recommendations include placing an emphasis on just culture; ensuring timely, systems-level investigations of all incidents; creating and facilitating participation in a national reporting system; incorporating Human Factors professionals at multiple levels of organizations; and establishing a national safety board for medicine

The motor and cognitive features of Parkinson's disease in patients with concurrent Gaucher disease over 2 years: a case series.

We report the cognitive features and progression of Parkinson's disease (PD) in five patients with concurrent Gaucher disease. The patients presented at an earlier age than patients with sporadic PD, as previously noted by others; but in contrast to many previous reports, our patients followed a variable clinical course. While two patients developed early cognitive deficits and dementia, three others remained cognitively intact over the follow-up period. Thus, in this small case series, PD in the context of GD more closely resembles idiopathic PD in terms of its clinical heterogeneity in contrast to PD associated with GBA heterozygote mutations.NIHR BRC and NIHR Senior Investigator, Rosetrees fundin