144,565 research outputs found

    Shift exhibition : Work implements for the legal immigrant (2018)

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    Exhibition: Shift. This exhibition is one of two that comprise a collaborative project between Blue Roof Museum, Chengdu, China and Wintec researchers, Hamilton, NZ. Wintec artists and Chengdu artists made up this exhibition and was curated by Ding Fenqi, Blue Roof Museum and Eliza Webster, Wallace Gallery , Morrinsville, NZ. Notions of community, technology and exchange were explored in the exhibition This sculptural work explores ideas of work, location/relocation and transferable skills

    Indeliable exhibition: Yellow river boat (2018): Trap (2018)

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    This exhibition is one of two that make up a cultural and artistic exchange project with Xi'an Art Museum, Xi'an City, Shaanxi Province, China; Waikato Museum, Hamilton, NZ; and Wintec researchers (Hamilton, NZ). Themes of exchange, community, identity and location were explored by the various practitioners involved in the project. These two sculptural works examine cultural practices of food gathering in relationship to community

    cAMP-Inhibits Cytoplasmic Phospholipase A(2) and Protects Neurons against Amyloid-beta-Induced Synapse Damage

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    A key event in Alzheimerā€™s disease (AD) is the production of amyloid-Ī² (AĪ²) peptides and the loss of synapses. In cultured neurons AĪ² triggered synapse damage as measured by the loss of synaptic proteins. Ī±-synuclein (Ī±SN), aggregates of which accumulate in Parkinsonā€™s disease, also caused synapse damage. Synapse damage was associated with activation of cytoplasmic phospholipase A2 (cPLA2), an enzyme that regulates synapse function and structure, and the production of prostaglandin (PG) E2. In synaptosomes PGE2 increased concentrations of cyclic adenosine monophosphate (cAMP) which suppressed the activation of cPLA2 demonstrating an inhibitory feedback system. Thus, AĪ²/Ī±SN-induced activated cPLA2 produces PGE2 which increases cAMP which in turn suppresses cPLA2 and, hence, its own production. Neurons pre-treated with pentoxifylline and caffeine (broad spectrum phosphodiesterase (PDE) inhibitors) or the PDE4 specific inhibitor rolipram significantly increased the AĪ²/Ī±SN-induced increase in cAMP and consequently protected neurons against synapse damage. The addition of cAMP analogues also inhibited cPLA2 and protected neurons against synapse damage. These results suggest that drugs that inhibit AĪ²-induced activation of cPLA2 and cross the bloodā€“brain barrier may reduce synapse damage in AD

    The electric potential of particles in interstellar space released from a nuclear waste payload

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    Mechanisms for charging a grain in the interplanetary medium include: (1) capture of solar wind electrons; (2) capture of solar wind protons; (3) ejection of electrons through the photoelectric effect due to the solar radiation; (4) escape of beta particles from beta emitters in the grain; and (5) escape of alpha particles from alpha emitters in the grain. The potentials on both nonradioactive and radioactive grains are considered with relation to particle size and time, and the distance from the Sun. Numerical results are presented where the waste mix is assumed to be PW-4b

    Reduction of the one-dimensional X-ray scattering data on mirror flats at NASA/Marshall Space Flight Center

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    Data on the scattering of X-rays from various mirror flats obtained from different vendors. The scattering data discussed in this section is obtained by a one dimensional proportional counter at X-ray energies of 8.06, 6.4 and 2.99 keV. X-rays are generated at one end of a 312.4m long tube which is under vacuum. This long tube provides a parallel beam of X-rays which is then collimated by a slit and allowed to scatter from a pair of mirror flats at small grazing angles of incidence. The slit and mirrors assembly is placed 182.4 meters from the other end of the tube where the proportional counter detector is located. The detector is sitting on an optical table which is pivoted so that it can rotate to intercept X-rays at a range of spatial locations. The optical table pivot is located 2.78 meters in front of the detector, and has an operational angular range of 350 arc minutes. Measured from the position of the mirror, this total angular range of the data is (350) (2.78/182.4) = 5.33 arcminutes

    Vortex Fluctuations in the Critical Casimir Effect of Superfluid and Superconducting Films

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    Vortex-loop renormalization techniques are used to calculate the magnitude of the critical Casimir forces in superfluid films. The force is found to become appreciable when size of the thermal vortex loops is comparable to the film thickness, and the results for T < Tc are found to match very well with perturbative renormalization theories that have only been carried out for T > Tc. When applied to a high-Tc superconducting film connected to a bulk sample, the Casimir force causes a voltage difference to appear between the film and bulk, and estimates show that this may be readily measurable.Comment: 4 pages, 5 figures, Revtex 4, typo correctio

    VLA observations of a sample of galaxies with high far-infrared luminosities

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    Preliminary results are presented from a radio survey of galaxies detected by the IRAS minisurvey. It was found that the main difference between galaxies selected in the far infrared and those selected in the optical is that the former have higher radio luminosities and that the radio emission is more centrally concentrated. There is some evidence that the strong central radio sources in the galaxies selected in the infrared are due to star formation, the star formation rate divided by the volume in which the star formation is occuring is 100 to 1000 times greater in the galaxies selected in the infrared than in the disks of normal galaxies

    Neuroscientistsā€™ everyday experiences of ethics: The interplay of regulatory, professional, personal and tangible ethical spheres

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    Copyright @ 2013 The Authors. This article has been published using OnlineOpen. Re-use of this article is permitted in accordance with the Terms and Conditions set out at http://wileyonline library.com/onlineopen#OnlineOpen_Terms.The ethical issues neuroscience raises are subject to increasing attention, exemplified in the emergence of the discipline neuroethics. While the moral implications of neurotechnological developments are often discussed, less is known about how ethics intersects with everyday work in neuroscience and how scientists themselves perceive the ethics of their research. Drawing on observation and interviews with members of one UK group conducting neuroscience research at both the laboratory bench and in the clinic, this article examines what ethics meant to these researchers and delineates four specific types of ethics that shaped their day-to-day work: regulatory, professional, personal and tangible. While the first three categories are similar to those identified elsewhere in sociological work on scientific and clinical ethics, the notion of ā€˜tangible ethicsā€™ emerged by attending to everyday practice, in which these scientistsā€™ discursive distinctions between right and wrong were sometimes challenged. The findings shed light on how ethical positions produce and are, in turn, produced by scientific practice. Informing sociological understandings of neuroscience, they also throw the category of neuroscience and its ethical specificity into question, given that members of this group did not experience their work as raising issues that were distinctly neuro-ethical.Wellcome Trus
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