2,146 research outputs found
A model for fluvial bedrock incision by impacting suspended and bed load sediment
A mechanistic model is derived for the rate of fluvial erosion into bedrock by abrasion from uniform size particles that impact the bed during transport in both bed and suspended load. The erosion rate is equated to the product of the impact rate, the mass loss per particle impact, and a bed coverage term. Unlike previous models that consider only bed load, the impact rate is not assumed to tend to zero as the shear velocity approaches the threshold for suspension. Instead, a given sediment supply is distributed between the bed and suspended load by using formulas for the bed load layer height, bed load velocity, logarithmic fluid velocity profile, and Rouse sediment concentration profile. It is proposed that the impact rate scales linearly with the product of the near-bed sediment concentration and the impact velocity and that particles impact the bed because of gravitational settling and advection by turbulent eddies. Results suggest, unlike models that consider only bed load, that the erosion rate increases with increasing transport stage (for a given relative sediment supply), even for transport stages that exceed the onset of suspension. In addition, erosion can occur if the supply of sediment exceeds the bed load transport capacity because a portion of the sediment load is transported in suspension. These results have implications for predicting erosion rates and channel morphology, especially in rivers with fine sediment, steep channel-bed slopes, and large flood events
Formation of Box Canyon, Idaho, by megaflood: implications for seepage erosion on Earth and Mars
Amphitheater- headed canyons have been used as diagnostic indicators of erosion by groundwater seepage, which has important implications for landscape evolution on Earth and astrobiology on Mars. Of perhaps any canyon studied, Box Canyon, Idaho, most strongly meets the proposed morphologic criteria for groundwater sapping because it is incised into a basaltic plain with no drainage network upstream, and approximately 10 cubic meters per second of seepage emanates from its vertical headwall. However, sediment transport constraints, ^4He and ^14C dates, plunge pools, and scoured rock indicate that a megaflood (greater than 220 cubic meters per second) carved the canyon about 45,000 years ago. These results add to a growing recognition of Quaternary catastrophic flooding in the American northwest, and may imply that similar features on Mars also formed by floods rather than seepage erosion
The search for a topographic signature of life.
Landscapes are shaped by the uplift, deformation and breakdown of bedrock and the erosion, transport and deposition of sediment. Life is important in all of these processes. Over short timescales, the impact of life is quite apparent: rock weathering, soil formation and erosion, slope stability and river dynamics are directly influenced by biotic processes that mediate chemical reactions, dilate soil, disrupt the ground surface and add strength with a weave of roots. Over geologic time, biotic effects are less obvious but equally important: biota affect climate, and climatic conditions dictate the mechanisms and rates of erosion that control topographic evolution. Apart from the obvious influence of humans, does the resulting landscape bear an unmistakable stamp of life? The influence of life on topography is a topic that has remained largely unexplored. Erosion laws that explicitly include biotic effects are needed to explore how intrinsically small-scale biotic processes can influence the form of entire landscapes, and to determine whether these processes create a distinctive topography
Taste Manipulation and Swallowing Mechanics in Trauma-Related Sensory-Based Dysphagia
Purpose: This study explored the effects of highconcentration taste manipulation trials on swallow function in persons with sensory-based dysphagia.
Method: Dysphagia researchers partnered with clinical providers to prospectively identify traumatically injured U.S. military service members (N = 18) with sensorybased dysphagia as evidenced by delayed initiation and/or decreased awareness of residue/penetration/ aspiration. Under videofluoroscopy, participants swallowed trials of 3 custom-mixed taste stimuli: unflavored (40% weight/volume [wt/vol] barium sulfate in distilled water), sour (2.7%wt/vol citric acid in 40% wt/vol barium suspension), and sweet–sour (1.11% wt/vol citric acid plus 8% wt/vol sucrose in 40% wt/vol barium suspension). Trials were analyzed and compared via clinical rating tools (the Modified Barium Swallow Impairment Profile [Martin-Harris et al., 2008] and the Penetration-Aspiration Scale [Rosenbek, Robbins, Roecker, Coyle, & Wood, 1996]). Additionally, a computational analysis of swallowing mechanics (CASM) was applied to a subset of 9 swallows representing all 3 tastants from 3 participants.
Results: Friedman’s tests for the 3 stimuli revealed significantly (p \u3c .05) improved functional ratings for Penetration-Aspiration Scale and pharyngoesophageal opening. CASM indicated differences in pharyngeal swallowing mechanics across all tastant comparisons (p ≤ .0001). Eigenvectors revealed increased tongue base retraction, hyoid elevation, and pharyngeal shortening for sweet–sour and, to a lesser extent, sour than for unflavored boluses.
Conclusion: Advantageous changes in certain parameters of oropharyngeal swallowing physiology were noted with high-intensity tastants per both clinical ratings and subsequent CASM, suggesting potential therapeutic application for taste manipulation
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The Classical Pink-Eyed Dilution Mutation Affects Angiogenic Responsiveness
Angiogenesis is the process by which new blood vessels are formed from existing vessels. Mammalian populations, including humans and mice, harbor genetic variations that alter angiogenesis. Angiogenesis-regulating gene variants can result in increased susceptibility to multiple angiogenesis-dependent diseases in humans. Our efforts to dissect the complexity of the genetic diversity that regulates angiogenesis have used laboratory animals due to the availability of genome sequence for many species and the ability to perform high volume controlled breeding. Using the murine corneal micropocket assay, we have observed more than ten-fold difference in angiogenic responsiveness among various mouse strains. This degree of difference is observed with either bFGF or VEGF induced corneal neovascularization. Ongoing mapping studies have identified multiple loci that affect angiogenic responsiveness in several mouse models. In this study, we used F2 intercrosses between C57BL/6J and the 129 substrains 129P1/ReJ and 129P3/J, as well as the SJL/J strain, where we have identified new QTLs that affect angiogenic responsiveness. In the case of AngFq5, on chromosome 7, congenic animals were used to confirm the existence of this locus and subcongenic animals, combined with a haplotype-based mapping approach that identified the pink-eyed dilution mutation as a candidate polymorphism to explain AngFq5. The ability of mutations in the pink-eyed dilution gene to affect angiogenic response was demonstrated using the p-J allele at the same locus. Using this allele, we demonstrate that pink-eyed dilution mutations in Oca2 can affect both bFGF and VEGF-induced corneal angiogenesis
Influence of bed patchiness, slope, grain hiding, and form drag on gravel mobilization in very steep streams
Steep streams are a major portion of channel networks and provide a link to transport sediment from hillslopes to lower gradient rivers. Despite their importance, key unknowns remain, perhaps foremost of which is evaluating in steep streams empirical laws for fluvial sediment transport developed for low-gradient rivers. To address this knowledge gap, we painted sediment in situ over 3 years to monitor incipient sediment motion and sediment-patch development in five small (drainage areas of 0.04–2 km^2) and steep (slopes of 5–37%) tributaries of Elder Creek, California, United States. We found that channel beds organized into size-sorted sediment patches which displayed active fluvial transport of gravel annually, consistent year-to-year patch median grain sizes, partial transport of bed material, and significantly higher values of critical Shields stress for incipient sediment motion compared to that observed for lower gradient rivers. The high critical Shields stresses (up to ≈0.5 for the median grain size) agree within a factor of ~3 to theoretical predictions which account for slope-dependent hydraulics, grain hiding, and sediment patches. For grains of approximately the same size as the roughness length scale, slope-dependent hydraulics and bed patchiness are the dominant controls on critical Shields stress values, while grain hiding is important for grains larger or smaller than the roughness length scale. Form drag exists in our monitored tributaries but has a smaller influence than the above effects. Our field observations show fluvial processes contribute to sediment mobilization in steep channels which are often considered to be dominated by debris flows
Floor- or ceiling-sliding for chemically active, gyrotactic, sedimenting Janus particles
Surface bound catalytic chemical reactions self-propel chemically active
Janus particles. In the vicinity of boundaries, these particles exhibit rich
behavior, such as the occurrence of wall-bound steady states of "sliding". Most
active particles tend to sediment as they are density mismatched with the
solution. Moreover Janus spheres, which consist of an inert core material
decorated with a cap-like, thin layer of a catalyst, are gyrotactic
("bottom-heavy"). Occurrence of sliding states near the horizontal walls
depends on the interplay between the active motion and the gravity-driven
sedimentation and alignment. It is thus important to understand and quantify
the influence of these gravity-induced effects on the behavior of model
chemically active particles moving near walls. For model gyrotactic,
self-phoretic Janus particles, here we study theoretically the occurrence of
sliding states at horizontal planar walls that are either below ("floor") or
above ("ceiling") the particle. We construct "state diagrams" characterizing
the occurrence of such states as a function of the sedimentation velocity and
of the gyrotactic response of the particle, as well as of the phoretic mobility
of the particle. We show that in certain cases sliding states may emerge
simultaneously at both the ceiling and the floor, while the larger part of the
experimentally relevant parameter space corresponds to particles that would
exhibit sliding states only either at the floor or at the ceiling or there are
no sliding states at all. These predictions are critically compared with the
results of previous experimental studies and our experiments conducted on
Pt-coated polystyrene and silica-core particles suspended in aqueous hydrogen
peroxide solutions.Comment: Total number of pages: 33, Number of figures: 18. The video files, as
mentioned in the supplementary material will be provided by the corresponding
author upon reques
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