Parameter space exploration of an ocean general circulation model using an isopycnal mixing parameterization

In this study we have employed statistical methods to efficiently design experiments and analyze output of an ocean general circulation model that uses an isopycnal mixing parameterization. Full ranges of seven inputs are explored using 51 numerical experiments. Fifteen of the cases fail to reach satisfactory equilibria. These are attributable to numerical limitations specific to the isopycnal model. Statistical approximating functions are evaluated using the remaining cases to determine the dependency of each of the six scalar outputs on the inputs. With the exception of one output, the approximating functions perform well. Known sensitivities, particularly the importance of diapycnal (vertical) eddy diffusivity and wind stress, are reproduced. The sensitivities of the model to two numerical constraints specific to the isopycnal parameterization, maximum allowable isopycnal slope and horizontal background eddy diffusivity, are explored. Isopycnal modelling issues, convection reduction and the Veronis effect, are examined and found to depend crucially on the isopycnal modelling constraints

The characterization and role of aeolian deposition on water quality, McMurdo Dry Valleys, Antarctica

The connection of ecosystems by wind-driven transport of material has become a topic of increasing interest and importance. Less than 1% of dust transported worldwide is exported to the Southern Ocean and Antarctic cryosphere; however, aeolian transport on the Antarctic continent is predominantly locally derived from the abrasion of bedrock. The deposition of the aeolian material is integral to nutrient and solute dispersal in the Antarctic ecosystem. This is particularly true in the ice-free areas of Antarctica, such as the McMurdo Dry Valleys (MDV), where aeolian material deposited in the aquatic system is solubilized during the melt season. The material is predominantly locally-derived from the abrasion of bedrock. In this study, a two-step leaching experiment simulates the melt season and we quantify the flux of solutes and nutrients to the aquatic ecosystem. Soluble salts were removed from the aeolian material first during cold water leaching followed by an increase in carbonate and silicate dissolution during freeze–thaw. Major ion fluxes on glaciers and lakes are at least two orders of magnitude greater than nutrient fluxes. However, the fluxes derived from these experiments are less than the estimated flux from streams to lakes and probably represent minima. Aeolian redistribution of local soils is important because they are the only source of new solutes and nutrients to the aquatic ecosystem of the MDV

A Roadmap for Using NSF Cyberinfrastructure with InCommon

This document provides a Roadmap for using the InCommon identity federation to enable researchers to access NSF cyberinfrastructure (CI) via their campus authentication service. It presents benefits and challenges of using InCommon for NSF cyberinfrastructure, and guidance in overcoming the challenges.NSF OCI-1040777, IU Pervasive Technology Institut

Bioresorbable Film for the Prevention of Adhesion to the Anterior Spine After Anterolateral Discectomy

Background context The development of scar tissue and adhesions postoperatively is a natural consequence of healing but can be associated with medical complications and render reoperation difficult. Many biocompatible products have been evaluated as barriers or deterrents to adhesions. Purpose To evaluate the efficacy of a bioresorbable polylactide film as a barrier to adhesion formation after anterolateral discectomy. Study design Experimental study. Methods Seven, skeletally mature female sheep underwent a retroperitoneal approach to the anterolateral lumbar spine. A discectomy was performed at two levels with an intervening unoperated disc site. One site was treated with a polylactide film barrier (Hydrosorb Shield; MacroPore Biosurgery, San Diego, CA) affixed with tacks manufactured from the same material. The second site was left untreated. Treatment and control sites were randomly assigned. Postmortem analysis included scar tenacity scoring on five spines and histological evaluation on two spines. Results The application of the Hydrosorb film barrier allowed a definite dissection plane during scar tenacity scoring and there was a significant difference in the development of adhesions to the disc between the control and treated sites. Histological evaluation revealed evidence of barrier formation to scar tissue and no significant adverse inflammatory reactions. Conclusions Hydrosorb Shield appears to be an effective postoperative barrier to scar tissue adhesion after anterolateral discectomy. The use of polylactide tacks was beneficial to affix the barrier film in place. Safety issues associated with delayed healing or adverse response to the film or tacks were not observed. Hydrosorb film may be useful as an antiadhesion barrier facilitating dissection during surgical revision in anterior approaches to the spine. Further studies are indicated to evaluate the performance of the bioresorbable material as an antiadhesion barrier in techniques of spinal fusion and disc replacement

Antarctic streams as a potential source of iron for the Southern Ocean

Due to iron’s role in oceanic primary production, there has been great interest in quantifying the importance of Fe in regions where concentrations are very low and macronutrients, nitrate and phosphate, are available. Measurements of filterable (i.e., \u3c0.4 μm) Fe concentrations in streams from Taylor Valley, McMurdo Dry Valleys, Antarctica, suggest that coastal-zone stream Fe input to the Southern Ocean could potentially play an important role in primary production in nearshore regions. Filterable Fe (fFe) data from streams in the McMurdo Dry Valleys were used to represent glacier meltwater that flows through ice-free landscape with the potential of transporting Fe to the Antarctic coastal zone. Estimates of potential fFe flux to the Antarctic Peninsula region using our mean fFe concentration of 10.6 µg L–1 combined with an estimate of ice-free area for the Antarctic Peninsula result in an fFe flux of 1.2 × 107 g yr–1. Although small compared to iceberg and aeolian Fe fluxes, future stream input to the Southern Ocean could increase due to glacier retreat and melting, thus increasing the fFe flux from glacier meltwater streams

Paroxysmal fascicular tachycardia and ventricular tachycardia due to mechanical stimulation by a mitral valve prosthesis

Electrophysiologic studies were performed in a woman who had two varieties of paroxysmal wide QRS tachycardia after mitral valve replacement with a Starr-Edwards prosthesis. One tachycardia originated in the left anterior fascicle; QRS complexes were 100 ms wide and resembled right bundle branch block with left posterior fascicular block, and a His bundle potential preceded each QRS by an interval of 20 ms (compared with 50 ms during sinus rhythm). The other tachycardia originated in the left ventricle. Clinical and echocardiographic observations suggested that the tachycardias were caused by mechanical stimulation of the interventricular septum by the mitral prosthesis

Sustained Software for Cyberinfrastructure - Analyses of Successful Efforts with a Focus on NSF-Funded Software

Reliable software that provides needed functionality is clearly essential for an effective distributed cyberinfrastructure (CI) that supports comprehensive, balanced, and flexible distributed CI that, in turn, supports science and engineering applications. The purpose of this study was to understand what factors lead to software projects being well sustained over the long run, focusing on software created with funding from the US National Science Foundation (NSF) and/or used by researchers funded by the NSF. We surveyed NSF-funded researchers and performed in-depth studies of software projects that have been sustained over many years. Successful projects generally used open-source software licenses and employed good software engineering practices and test practices. However, many projects that have not been well sustained over time also meet these criteria. The features that stood out about successful projects included deeply committed leadership and some sort of user forum or conference at least annually. In some cases, software project leaders have employed multiple financial strategies over the course of a decades-old software project. Such well-sustained software is used in major distributed CI projects that support thousands of users, and this software is critical to the operation of major distributed CI facilities in the US. The findings of our study identify some characteristics of software that is relevant to the NSF-supported research community, and that has been sustained over many years