36 research outputs found
The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma
Get PDFWe describe the landscape of somatic genomic alterations of 66 chromophobe renal cell carcinomas (ChRCCs) based on multidimensional and comprehensive characterization, including mitochondrial DNA (mtDNA) and whole genome sequencing. The result is consistent that ChRCC originates from the distal nephron compared to other kidney cancers with more proximal origins. Combined mtDNA and gene expression analysis implicates changes in mitochondrial function as a component of the disease biology, while suggesting alternative roles for mtDNA mutations in cancers relying on oxidative phosphorylation. Genomic rearrangements lead to recurrent structural breakpoints within TERT promoter region, which correlates with highly elevated TERT expression and manifestation of kataegis, representing a mechanism of TERT up-regulation in cancer distinct from previously-observed amplifications and point mutations
Lars Svenonius. A theorem on permutations in models. Theoria (Lund), vol. 25 (1959), pp. 173–178.
No full textMichael O. Rabin. A simple method for undecidability proofs and some applications. Logic, methodology and philosophy of science, Proceedings of the 1964 International Congress, edited by Yehoshua Bar-Hillel, Studies in logic and the foundations of mathematics, North-Holland Publishing Company, Amsterdam1965, pp. 38–68.
No full textLars Svenonius. Some problems in logical model-theory. Library of Theoria, no. IV. C. W. K. Gleerup, Lund, and Ejnar Munksgaard, Copenhagen, 1960, 43 pp.
No full textEvaluation de la qualité des greffons provenant de donneurs décédés non contrôlés après arrêt cardiaque
No full textLYON1-BU Santé (693882101) / SudocSudocFranceF
Carol R. Karp. Languages with expressions of infinite length. Studies in logic and the foundations of mathematics. North-Holland Publishing Company, Amsterdam1964, xix + 183 pp.
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