Risk factors of post renal transplant anaemia among Sudanese patients, a study in three renal transplant centres

<p>Abstract</p> <p>Background</p> <p>There is a relative lack of recent information about late post kidney transplantation anaemia (PTA), especially in the developing countries; data are scarce about the prevalence and risk factors of PTA. Sudan was a leading country in Africa and Arab world in kidney transplantation. The first kidney transplantation in Sudan was in 1973.</p> <p>Methods</p> <p>This is a cross-sectional hospital analytic study enrolling all kidney transplanted recipients following in the transplant referral clinics at Ahmed Gassim, Selma and Ibn Sina Hospitals, Khartoum/Sudan, in the period from 1/8/2010 to 1/9/2010, clinical and laboratory data were obtained from 114 patients, anaemia was defined as Hb levels of < 13 g/dl for male patients and < 12 g/dl for female patients, exclusion criteria were pregnancy, below 18 years old patients, multiple organ transplantation, and patients with less than one year from the transplantation.</p> <p>Results</p> <p>The study showed that 39.5% of the patients were anaemic. Univariate analysis showed that late PTA is significantly associated with not using Erythropoietin (EPO) in the pre-transplant period (p = < 0.001), history of rejection (p = 0.003), longer time from transplantation (p = 0.015), and eGFR (p < 0.0001). Multivariate analysis showed that eGFR (p = < 0.001) and not use of EPO in the pre transplant period (p < 0.001) are strong predictors of PTA. The use of Angiotensin converting enzyme inhibitors/Angiotensin receptors blockers (ACEI/ARB), immunosuppressive treatments, presence or absence of co-morbidities, donor type and donor age are not significantly associated with late PTA.</p> <p>Conclusion</p> <p>The study concluded that late PTA is common and under recognized. Risk factors for late PTA include renal dysfunction, history of rejection, longer duration of transplantation and not using EPO in the pre-transplant period. Renal dysfunction and not using EPO in the pre-transplant period are major predictors of late PTA.</p

Archaeobotanical investigations of Late Neolithic lakeshore settlements (Lake Biel, Switzerland)

Neolithikum - Schweiz - Seeufersiedlung - Samen und Früchte - Archäobotani

Plant economies and village life in Neolithic lake dwellings at the time of the Alpine Iceman

This paper gives an overview of domesticated and wild plants used during the 2nd half of the 4th millennium B.C. (cal.) in a region within a semicircle of ca. 100 km radius around the find spot of the Iceman. The landscape considered lies north of the main alpine chain and includes Central to Eastern Switzerland and SW-Germany (mainly sites at the lakes Zug, Zürich, Constance, Upper Swabia (the Federsee region) and western Bavaria). From this part of Central Europe the plant remains of many well preserved Lake dwelling sites were investigated during the last decades and much is known about the daily life in these villages. Probably contemporaneous with the Iceman&rsquo;s lifetime is one of the best investigated settlements, Arbon Bleiche 3 at the southern shore of Lake Constance. A comparison of the Iceman´s artefacts and plant macro remains with the findings in the considered lake dwellings shows striking similarities, but also differences. Based on domestic plants found with the Iceman his southern provenience can be corroborated. He used domestic as well as wild plants, very similar as the contemporaries of the lakeside villages. The detailed knowledge of the manifold activities in the lakeshore village of Arbon Bleiche 3 allows us to show a rather realistic picture about the daily life circumstances at the time of the Iceman