A quantum-like description of the planetary systems

The Titius-Bode law for planetary distances is reviewed. A model describing the basic features of this rule in the "quantum-like" language of a wave equation is proposed. Some considerations about the 't Hooft idea on the quantum behaviour of deterministic systems with dissipation are discussed.Comment: LaTex file, 17 pages, no figures. Version published in Foundations of Physics, August 200

Antagonismo de isolados de Trichoderma contra fungos fitopatogênicos habitantes do solo.

Para o diminuir os prejuízos na produção de hortaliças causados por patógenos habitantes do solo, uma das alternativas é o controle biológico. Este trabalho teve como objetivo avaliar o antagonismo in vitro de seis isolados amazônicos de Trichoderma spp. provenientes da coleção do INPA que foram avaliados em experimentos anteriores como controladores da queima-da-saia em alface (Rhizoctonia solani) e de podridão-de-Sclerotium (Sclerotium rolfsii) em pimentão e tomate

Seleção de isolados de Trichoderma spp. para controle biológico de Sclerotium rolfsii em tomateiros.

Doenças causadas por patógenos habitantes do solo são de difícil controle e causam sérios prejuízos na produção de espécies olerícolas no Amazonas. A pesquisa objetiva avaliar seis isolados amazônicos de Trichoderma spp. que mostraram potencial em experimentos anteriores no controle de podridão-de-Sclerotium (Sclerotium rolfsii) em tomateiro (Solanum lycopersicum)

A Heat‐Activated Drug‐Delivery Platform Based on Phosphatidyl‐(oligo)‐glycerol Nanocarrier for Effective Cancer Treatment

The potential of cancer drugs is not fully exploited due to low tumor uptake and occurrence of systemic side effects, limiting maximum tolerated dose. Actively targeted nanocarriers improve efficacy while minimizing off‐target toxicity. Herein, it is the first time a drug‐delivery platform for heat‐triggered intravascular drug release is described, based on synthetic phosphatidyl‐(oligo)‐glycerols from organic synthesis to preclinical investigation in feline patients. For the nanocarrier formulated doxorubicin (DOX), superior tumor drug delivery and antitumor activity compared with free DOX, conventional liposomal DOX (Caelyx), and temperature‐sensitive lysolipid‐containing DOX‐liposomes in rat sarcoma are demonstrated. In a comparative oncological study with neoadjuvant treatment of feline sarcoma, a metabolic response determined with 18 F‐FDG‐positron emission tomography/magnetic resonance imaging (PET/MRI) and histopathological response after tumor resection are significantly better compared with free DOX, potentially by overcoming drug resistance based on improved intratumoral drug distribution. This novel drug‐delivery platform has great potential for the treatment of locally advanced tumors in humans