The use of options for tax deferral.

Thesis. 1977. M.S.--Massachusetts Institute of Technology. Alfred P. Sloan School of Management.MICROFICHE COPY AVAILABLE IN ARCHIVES AND DEWEY.Bibliography : leaves 140-144.M.S

Crystal Structure of Glycoprotein C from a Hantavirus in the Post-fusion Conformation.

Hantaviruses are important emerging human pathogens and are the causative agents of serious diseases in humans with high mortality rates. Like other members in the Bunyaviridae family their M segment encodes two glycoproteins, GN and GC, which are responsible for the early events of infection. Hantaviruses deliver their tripartite genome into the cytoplasm by fusion of the viral and endosomal membranes in response to the reduced pH of the endosome. Unlike phleboviruses (e.g. Rift valley fever virus), that have an icosahedral glycoprotein envelope, hantaviruses display a pleomorphic virion morphology as GN and GC assemble into spikes with apparent four-fold symmetry organized in a grid-like pattern on the viral membrane. Here we present the crystal structure of glycoprotein C (GC) from Puumala virus (PUUV), a representative member of the Hantavirus genus. The crystal structure shows GC as the membrane fusion effector of PUUV and it presents a class II membrane fusion protein fold. Furthermore, GC was crystallized in its post-fusion trimeric conformation that until now had been observed only in Flavi- and Togaviridae family members. The PUUV GC structure together with our functional data provides intriguing evolutionary and mechanistic insights into class II membrane fusion proteins and reveals new targets for membrane fusion inhibitors against these important pathogens.Work with mutant Gc proteins was funded by FONDECYT 1140050 and Basal PFB-16 grants from CONICYT (to NDT), YM was supported by a Senior Research Fellowship from the Wellcome Trust, grant no. 101908/Z/13/Z,This is the final version of the article. It first appeared from PLOS via https://doi.org/10.1371/journal.ppat.100594

A Discussion of the Probability of Undetected Error for Cyclic Codes on a Bursty Renewal Channel

Coordinated Science Laboratory was formerly known as Control Systems LaboratoryJoint Services Electronics Program / DAAB-07-67-C-0199National Science Foundation / GK-24879U of I OnlyRestricted to UIUC communit

The Japanese right-wing: 1926-1941

Master of ArtsCenter for Japanese StudiesUniversity of Michiganhttps://deepblue.lib.umich.edu/bitstream/2027.42/145069/1/cjsmat_366.pdf45

A Discussion of the Probability of Undetected Error for Cyclic Codes on a Bursty Renewal Channel

Coordinated Science Laboratory was formerly known as Control Systems LaboratoryJoint Services Electronics Program / DAAB-07-67-C-0199National Science Foundation / GK-24879U of I OnlyRestricted to UIUC communit

The Complete Impact of Bicycle Use: Analyzing the Environmental Impact and Initiative of the Bicycle Industry

Bicycles are commonly considered a tool for environmental solutions. Increasing ridership reduces fossil fuel consumption, eases traffic congestion, and improves public health by reducing risks associated with obesity (Bikes Belong; Hall, 2012). While these impacts are undeniably important to create a more sustainable society, they fail to bring up an important question: are bicycles produced sustainably? If they are not, increasingly strict environmental regulations on substances in manufacturing, waste water discharge, and solid waste disposal, along with the rising cost of energy may cause supply chain disruption through shut downs of non-compliant suppliers and impacts on the cost of shipping. The companies that prosper will be ones that proactively work with their suppliers to ensure these risks are mitigated. The goal of this report was to quantitatively analyze the sustainability of manufacturing processes used to produce Specialized Bicycle Component’s bicycles and to qualitatively determine the current state of interest for sustainably made bikes. A life cycle assessment (LCA) was performed to quantify the impact of a Specialized Roubaix 56cm frameset, a Specialized Allez 56cm frameset, a DT Swiss R24 Spline wheelset, and a SRAM PC 1071 bicycle chain. The Outdoor Industry Association Equipment Index was piloted to assess Specialized as a brand and the two framesets considered. Finally, a consumer survey and a media analysis were conducted to evaluate progress within the industry and hypothesize consumer perceptions