4,083 research outputs found
On the possibility of q-scaling in high energy production processes
It has been noticed recently that transverse momenta (p_T) distributions
observed in high energy production processes exhibit remarkably universal
scaling behaviour. This is the case when a suitable variable replaces the usual
p_T. On the other hand, it is also widely known that transverse momentum
distributions in general follow a power-like Tsallis distribution, rather than
an exponential Boltzmann-Gibbs, with a (generally energy dependent)
nonextensivity parameter q. Here we show that it is possible to choose a
suitable variable such that all the data can be fitted by the same Tsallis
distribution (with the same, energy independent value of the q-parameter). Thus
they exhibit q-scaling.Comment: Final version, accepted by J.Phys.
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Comparing predictions made by a prediction model, clinical score, and physicians Pediatric asthma exacerbations in the emergency department
Background: Asthma exacerbations are one of the most common medical reasons for children to be brought to the hospital emergency department (ED). Various prediction models have been proposed to support diagnosis of exacerbations and evaluation of their severity. Objectives: First, to evaluate prediction models constructed from data using machine learning techniques and to select the best performing model. Second, to compare predictions from the selected model with predictions from the Pediatric Respiratory Assessment Measure (PRAM) score, and predictions made by ED physicians.
Design: A two-phase study conducted in the ED of an academic pediatric hospital. In phase 1 data collected prospectively using paper forms was used to construct and evaluate five prediction models, and the best performing model was selected. In phase 2, data collected prospectively using a mobile system was used to compare the predictions of the selected prediction model with those from PRAM and ED physicians.
Measurements: Area under the receiver operating characteristic curve and accuracy in phase 1; accuracy, sensitivity, specificity, positive and negative predictive values in phase 2.
Results: In phase 1 prediction models were derived from a data set of 240 patients and evaluated using 10-fold cross validation. A naive Bayes (NB) model demonstrated the best performance and it was selected for phase 2. Evaluation in phase 2 was conducted on data from 82 patients. Predictions made by the NB model were less accurate than the PRAM score and physicians (accuracy of 70.7%, 73.2% and 78.0% respectively), however, according to McNemar’s test it is not possible to conclude that the differences between predictions are statistically significant.
Conclusion: Both the PRAM score and the NB model were less accurate than physicians. The NB model can handle incomplete patient data and as such may complement the PRAM score. However, it requires further research to improve its accuracy
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Using PICO to Align Medical Evidence with MDs Decision Making Models
Modern medicine is characterized by an “explosion” in clinical research information making practical application of Evidence-Based Medicine (EBM), problematic for many clinicians. We have developed a PICO-(evidence based search strategy focusing on Patient/Population, Intervention, Comparison and Outcome)-based framework for (indexing and retrieving medical evidence and we posit that the use of PICO allows for organizing evidence that is aligned with an MD’s decision making model. We describe a study where medical students evaluated our PICO-based approach and results show that students are eager to apply EBM but are hindered by a lack of specialist skills. Students reported that the PICO-based framework for organizing evidence provided an intuitive way of accessing and evaluating evidence and would be useful for their clinical tasks
Energy and Atomic Mass Dependence of Nuclear Stopping Power in Relativistic Heavy-Ion Collisions in Interacting Gluon Model
We present a Monte-Carlo simulation of energy deposition process in
relativistic heavy-ion collisions based on a new realization of the
Interacting-Gluon-Model (IGM) for high energy collisions. In particular
we show results for proton spectra from collisions of
S beam incident on S target and analyze the energy and mass
dependence of nuclear stopping power predicted by our model. Theoretical
predictions for proton rapidity distributions of both Pb + Pb
collisions at CERN SPS and Au + Au at
BNL RHIC are given.Comment: 10 pages in compressed uuencoded fil
Fluctuations of g-factors in metal nanoparticles: Effects of electron-electron interaction and spin-orbit scattering
We investigate the combined effect of spin-orbit scattering and
electron-electron interactions on the probability distribution of -factors
of metal nanoparticles. Using random matrix theory, we find that even a
relatively small interaction strength %(ratio of exchange constant and mean
level %spacing \spacing ) significantly increases -factor
fluctuations for not-too-strong spin-orbit scattering (ratio of spin-orbit rate
and single-electron level spacing 1/\tau_{\rm so} \spacing \lesssim 1), and
leads to the possibility to observe -factors larger than two.Comment: RevTex, 2 figures inserte
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A Task-based Support Architecture for Developing Point-of-care Clinical Decision Support Systems for the Emergency Department
Objectives: The purpose of this study was to create a task-based support architecture for developing clinical decision support systems (CDSSs) that assist physicians in making decisions at the point-of-care in the emergency department (ED). The backbone of the proposed architecture was established by a task-based emergency workflow model for a patient-physician encounter.
Methods: The architecture was designed according to an agent-oriented paradigm. Specifically, we used the O-MaSE (Organization-based Multi-agent System Engineering) method that allows for iterative translation of functional requirements into architectural components (e.g., agents). The agent-oriented paradigm was extended with ontology-driven design to implement ontological models representing knowledge required by specific agents to operate.
Results: The task-based architecture allows for the creation of a CDSS that is aligned with the task-based emergency workflow model. It facilitates decoupling of executable components (agents) from embedded domain knowledge (ontological models), thus supporting their interoperability, sharing, and reuse. The generic architecture was implemented as a pilot system, MET3-AE – a CDSS to help with the management of pediatric asthma exacerbation in the ED. The system was evaluated in a hospital ED.
Conclusions: The architecture allows for the creation of a CDSS that integrates support for all tasks from the task-based emergency workflow model, and interacts with hospital information systems. Proposed architecture also allows for reusing and sharing system components and knowledge across disease-specific CDSSs
Modified Hagedorn formula including temperature fluctuation - Estimation of temperatures at RHIC experiments -
We have systematically estimated the possible temperatures obtained from an
analysis of recent data on distributions observed at RHIC experiments.
Using the fact that observed distributions cannot be described by the
original Hagedorn formula in the whole range of transverse momenta (in
particular above 6 GeV/c), we propose a modified Hagedorn formula including
temperature fluctuation. We show that by using it we can fit
distributions in the whole range and can estimate consistently the relevant
temperatures, including their fluctuations.Comment: Some misprints corrected, references updated. To be published in Eur.
Phys. J. C (2006
An improved direct colorimetric method for the quantitative analysis of urinary hippuric acid as an index of toluene exposure
An improved direct colorimetric method for determining the concentration of urinary hippuric acid as an index of toluene exposure was described. One tenth ml of urine was diluted with 0.4 ml 0.01 M phosphate buffer H 6.9 and mixed with 0.5 ml pyridine. The mixture was layered on 0.2 ml benzenesulfonyl chloride. The reaction was started by mixing for one min with a mechanical shaker. The colored solution was allowed to stand for 30 min, diluted with 5 ml ethanol, and absorbance measured at 410 nm within 30 min after the dilution. The coefficient of variation of this method was 6% and the recovery 103% when urine contains about 0.2-0.5 mg hippuric acid per ml of urine. The concentration was linear up to 2.0 mg per ml hippuric acid in a specimen.</p
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