An Evaluation of The Effectiveness of Project Impact: Multicultural Academic Program Success At Kansas State University

Kansas State University created a suite of recruitment programs, which included Project Impact: Multicultural Academic Program Success (MAPS) to aid incoming college freshmen in their academic transition. This program is led by the Department of Multicultural Student Affairs in collaboration with the Colleges of Agriculture, Business, and Engineering. Each college hosts a group of ethnic minority students each year. The College of Agriculture’s Diversity Program Office (DPO) serves as the host for 10 students in its college, each year. This study covers 40 participants from 2016, 2017, 2018, and 2019 in the College of Agriculture. Data were collected using a pre-post Likert scale assessment and analyzed by descriptive statistics. The results showed that MAPS had an impact on student knowledge and interest level in Agriculture. That is, participants’ knowledge of agricultural sciences increased. The DPO will utilize results to further develop diverse recruitment and retention programs within the College of Agriculture

Assessing The Success of The 2020 Kansas State Research and Extension Summer Research Program: A Virtual Research Experience

Ethnic minorities, and specifically African American students are not participating in graduate programs at the same rate as non-minority students. In 2006, Kansas State University College of Agriculture Diversity Programs Office (DPO) established the Kansas State Research and Extension (KSRE) Summer Research Fellows Program to expose African American and other ethnic minority students to the agricultural sciences graduate research opportunities. Due to the Covid-19 pandemic, the 2020 KSRE Summer Research Fellows Program was held virtually to protect the health and safety of participants. The purpose of this study was to evaluate the effectiveness of the virtual program. Data from five 2020 participants were collected using a 5-point Likert scale assessment and analyzed as a case study and by descriptive statistics. As a result of this case study, participants successfully gained knowledge of graduate school and careers in agriculture. Findings will be utilized to further enhance student experience in the program

Optimal Pipeline Design with Increasing CO2 Flow Rates

AbstractWide deployment of carbon capture and storage (CCS) will require extensive transportation infrastructure, quite often in the form of pipelines. The rollout of such large-scale infrastructure would undoubtedly require very large investments. In regions with several CO2 emission sources, it is possible that not all of the major CO2 sources will implement CCS at the same time. Shared oversized pipeline designs are often proposed in order to form a “cluster” of CO2 sources and serve as the backbone for an expanding CO2 transportation infrastructure, to which emission sources will be connected. This paper analyses the economics of using oversized and parallel pipelines for different typical pipeline length and CO2 flow rate combinations. For new CCS projects, the expansion methodology presented in this paper can identify the optimal pipeline design that minimises the cost per tonne of CO2 avoided over the life of the project. For existing projects, the expansion methodology identifies the optimal pipeline design change, which may include either using an existing pipeline as CO2 supply increases or duplicating pipelines

Invasive Species Removal Promotes Habitat Restoration but Does Not Immediately Improve the Condition of a Threatened Plant Subspecies

Impacts of invasive species on rare species are relevant to conservation. We studied the response of Leedy’s roseroot Rhodiola integrifolia subsp. leedyi, a subspecies listed as threatened under the Endangered Species Act, to removal of the invasive species Japanese knotweed Fallopia japonica. Japanese knotweed has invaded the largest known population of Leedy’s roseroot, affecting about 10% of all Leedy’s roseroot in the world. Japanese knotweed shaded Leedy’s roseroot, but the two did not share belowground resources because of their position on cliffs. To study this interaction and, ultimately, to restore Leedy’s roseroot habitat to an open, high-light condition, we removed Japanese knotweed in a three-treatment block design. We measured Leedy’s roseroot abundance, growth, and reproduction in treatment blocks and in uninvaded areas before and after treatment. Compared with uninvaded areas, Japanese knotweed invasion negatively affected Leedy’s roseroot abundance, growth, and reproduction. Light interception by Japanese knotweed degraded the habitat for Leedy’s roseroot. Herbicide removal of Japanese knotweed resulted in increased light and temperature compared with untreated invaded plots but did not affect Leedy’s roseroot abundance, growth, or reproduction over the 2 y of our study. These results show that invasive species removal is conducive to restoring Leedy’s roseroot habitat, but recovery in the subspecies may lag behind restoration of the habitat, suggesting that additional action or time may be required to restore preinvasion performance of Leedy’s roseroot. Results of this study may inform restoration efforts for other systems and contribute to the literature on interspecific interactions

Openness to Diversity and Challenge: Assessment of Undergraduate Attitudes and Experiences in The College of Agriculture at Kansas State University

As society becomes more globally diverse, institutions of higher education have increased diversity programming for student success. Student openness to diversity and challenge has been found to have a large impact on changes in student attitudes, beliefs, and actions in the direction of greater tolerance to individual differences. This study uses regression analysis of survey data to measure (1) openness to diversity, and (2) diversity experience for students enrolled in the College of Agriculture at Kansas State University during the Fall Semester of 2020. Regression results indicate that student openness to diversity and challenge was found to be statistically associated with participation in diversity workshops, diversity class activities, and other personal and academic variables. The major implication of the statistical results is that there is an opportunity to influence student openness to diversity and challenge through enhanced programming for diversity appreciation and understanding as part of the university experience

Monocyte-mediated Tumoricidal Activity via the Tumor Necrosis Factor–related Cytokine, TRAIL

TRAIL (tumor necrosis factor [TNF]-related apoptosis-inducing ligand) is a molecule that displays potent antitumor activity against selected targets. The results presented here demonstrate that human monocytes rapidly express TRAIL, but not Fas ligand or TNF, after activation with interferon (IFN)-γ or -α and acquire the ability to kill tumor cells. Monocyte-mediated tumor cell apoptosis was TRAIL specific, as it could be inhibited with soluble TRAIL receptor. Moreover, IFN stimulation caused a concomitant loss of TRAIL receptor 2 expression, which coincides with monocyte acquisition of resistance to TRAIL-mediated apoptosis. These results define a novel mechanism of monocyte-induced cell cytotoxicity that requires TRAIL, and suggest that TRAIL is a key effector molecule in antitumor activity in vivo

Mid-Upper Arm Circumference based Nutrition Programming: evidence for a new approach in regions with high burden of Acute Malnutrition

In therapeutic feeding programs (TFP), mid-upper arm circumference (MUAC) shows advantages over weight-for-height Z score (WHZ) and is recommended by the World Health Organization (WHO) as an independent criterion for screening children 6-59 months old. Here we report outcomes and treatment response from a TFP using MUAC ≤118 mm or oedema as sole admission criteria for severe acute malnutrition (SAM)

Variation in the Analysis of Positively Selected Sites Using Nonsynonymous/Synonymous Rate Ratios: An Example Using Influenza Virus

Sites in a gene showing the nonsynonymous/synonymous rate ratio (ω) >1 have been frequently identified to be under positive selection. To examine the performance of such analysis, sites of the ω ratio >1 in the HA1 gene of H3N2 subtype human influenza viruses were identified from seven overlapping sequence data sets in this study. Our results showed that the sites of the ω ratio >1 were of significant variation among the data sets even though they targeted similar clusters, indicating that the analysis is likely to be either of low sensitivity or of low specificity in identifying sites under positive selection. Most (43/45) of the sites showing ω >1 calculated from at least one data set are involved in B-cell epitopes which cover less than a half sites in the protein, suggesting that the analysis is likely to be of low sensitivity rather than of low specificity. It was further found that the analysis sensitivity could not be enhanced by including more sequences or covering longer time intervals. Previously some reports also likely identified only a portion of the sites under positive selection in the viral gene using the ω ratio. Low sensitivity of the analysis may result from that some sites under positive selection in the gene are also under negative (purifying) selection simultaneously for functional constrains, and so their ω ratios could be <1. Theoretically, the sites under the two opposite selection forces at the same time favor only certain nonsynonymous changes, e.g. those changing the antigenicity of the gene and maintaining the gene function. This study also suggested that sometimes we can identify more sites under positive selection using the ω ratio by integrating the positively selected sites estimated from multiple data sets

Ouabain Stimulates a Na+/K+-ATPase-Mediated SFK-Activated Signalling Pathway That Regulates Tight Junction Function in the Mouse Blastocyst

The Na+/K+-ATPase plays a pivotal role during preimplantation development; it establishes a trans-epithelial ionic gradient that facilitates the formation of the fluid-filled blastocyst cavity, crucial for implantation and successful pregnancy. The Na+/K+-ATPase is also implicated in regulating tight junctions and cardiotonic steroid (CTS)-induced signal transduction via SRC. We investigated the expression of SRC family kinase (SFK) members, Src and Yes, during preimplantation development and determined whether SFK activity is required for blastocyst formation. Embryos were collected following super-ovulation of CD1 or MF1 female mice. RT-PCR was used to detect SFK mRNAs encoding Src and Yes throughout preimplantation development. SRC and YES protein were localized throughout preimplantation development. Treatment of mouse morulae with the SFK inhibitors PP2 and SU6656 for 18 hours resulted in a reversible blockade of progression to the blastocyst stage. Blastocysts treated with 10−3 M ouabain for 2 or 10 minutes and immediately immunostained for phosphorylation at SRC tyr418 displayed reduced phosphorylation while in contrast blastocysts treated with 10−4 M displayed increased tyr418 fluorescence. SFK inhibition increased and SFK activation reduced trophectoderm tight junction permeability in blastocysts. The results demonstrate that SFKs are expressed during preimplantation development and that SFK activity is required for blastocyst formation and is an important mediator of trophectoderm tight junction permeability