6,486 research outputs found
Crystal structure of 9-methacryloylanthracene
The authors would like to thank the Graduate College and Chemistry Department at Cleveland State University for support, the Ohio Supercomputing Center for a grant of computer time, and the National Science Foundation (CHE-0840446) for funds used to purchase the Bruker APEXII DUO X-ray diffractometer used in this research.Peer reviewedPublisher PD
Astronomy in the Cloud: Using MapReduce for Image Coaddition
In the coming decade, astronomical surveys of the sky will generate tens of
terabytes of images and detect hundreds of millions of sources every night. The
study of these sources will involve computation challenges such as anomaly
detection and classification, and moving object tracking. Since such studies
benefit from the highest quality data, methods such as image coaddition
(stacking) will be a critical preprocessing step prior to scientific
investigation. With a requirement that these images be analyzed on a nightly
basis to identify moving sources or transient objects, these data streams
present many computational challenges. Given the quantity of data involved, the
computational load of these problems can only be addressed by distributing the
workload over a large number of nodes. However, the high data throughput
demanded by these applications may present scalability challenges for certain
storage architectures. One scalable data-processing method that has emerged in
recent years is MapReduce, and in this paper we focus on its popular
open-source implementation called Hadoop. In the Hadoop framework, the data is
partitioned among storage attached directly to worker nodes, and the processing
workload is scheduled in parallel on the nodes that contain the required input
data. A further motivation for using Hadoop is that it allows us to exploit
cloud computing resources, e.g., Amazon's EC2. We report on our experience
implementing a scalable image-processing pipeline for the SDSS imaging database
using Hadoop. This multi-terabyte imaging dataset provides a good testbed for
algorithm development since its scope and structure approximate future surveys.
First, we describe MapReduce and how we adapted image coaddition to the
MapReduce framework. Then we describe a number of optimizations to our basic
approach and report experimental results comparing their performance.Comment: 31 pages, 11 figures, 2 table
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Opportunities to encourage mail order pharmacy delivery service use for diabetes prescriptions: a qualitative study.
BackgroundMedication non-adherence is a major contributor to poor outcomes in diabetes. Previous research has shown an association between use of mail order pharmacy delivery and better medication adherence, but little is known about the barriers and facilitators to mail order pharmacy use in diabetes patients. This qualitative study examined factors related to mail order pharmacy use versus traditional "brick and mortar" pharmacies to refill prescriptions.MethodsWe conducted four 90-min focus groups in 2016 among 28 diabetes patients in the Hawaii and Northern California regions of Kaiser Permanente, a large integrated health care delivery system. We queried participants on their preferred mode for refilling prescriptions and perceived barriers and facilitators of mail order pharmacy use. One researcher independently coded each focus group transcript, with two of these transcripts double-coded by a second researcher to promote reliability. We employed thematic analysis guided by the Capability, Opportunity, Motivation, and Behavior (COM-B) framework using NVivo 11 software.ResultsA total of 28 diabetes patients participated. Participants' average age was 64.1 years; 57% were female; and racial/ethnic backgrounds included Asian/Native Hawaiian/Pacific Islander (36%), Black/African-American (21%) Hispanic/Latino (7%), and non-Hispanic White (36%). Analysis uncovered 26 themes related to the decision to use mail order pharmacy, with each theme representing a barrier or facilitator mapped to the COM-B framework. Most themes (20/26) fell into the COM-B category of 'Opportunity.' Opportunity barriers to mail order pharmacy use included unpredictability of medication delivery date, concerns about mail security, and difficulty coordinating refill orders for multiple prescriptions. In contrast, facilitators included greater access and convenience (e.g., no need to wait in line or arrange transportation) compared to traditional pharmacies. Motivational facilitators to mail order pharmacy use included receiving a pharmacy benefit plan incentive of a free one-month supply of prescriptions.ConclusionsThis study found that while patients with diabetes may benefit from mail order pharmacy use, they perceive numerous barriers to using the service. These findings will inform the design of interventions and quality improvement initiatives to increase mail order pharmacy use, which in turn may improve medication adherence and outcomes in diabetes patients, across health care systems
Towards a Process Domain‐Sensitive Substrate Habitat Model for Sea Lampreys in Michigan Rivers
Habitat mapping is a common and often useful tool in the ecological management of rivers. The complex nature of fluvial processes, however, makes it difficult to predict the reach‐scale distribution of substrate habitat from landscape‐scale covariates. An option is to identify and partition a data set on boundaries of geomorphic process domains, within which the globally complex relationships between landscape, climate, and instream habitat may potentially be approximated by a simpler model. In this study, we used regression trees as a machine learning method for partitioning and identifying useful strata in a geographically extensive substrate habitat model for larvae of the sea lamprey Petromyzon marinus, an invasive and economically harmful species in the Laurentian Great Lakes. We used field survey data from over 5,000 substrate habitat transects collected in 43 watersheds of the Lower Peninsula of Michigan, and we created a geographic database of geographical information systems‐derived covariates that represent the principal geomorphic influences on substrate habitat. We created three trees in which tree splits delineated (1) spatially contiguous units, (2) noncontiguous units defined by values of the covariates, and (3) both contiguous and noncontiguous units. The adjusted R2 values of the three trees were 0.30, 0.30, and 0.32, respectively, and all three trees outperformed a single model fitted to the entire data set and a set of models fitted to each watershed individually. The trees identified useful stratifications of Michigan’s Lower Peninsula, important geomorphic influences on substrate habitat, and variation in the influence of geomorphic processes on substrate habitat across our study region. Conservation and management applications of our model predictions and tree‐based stratifications include sea lamprey population modeling, habitat survey design, and evaluation of dam removal.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141668/1/tafs0313.pd
Genomic islands of divergence in the Yellow Tang and the Brushtail Tang Surgeonfishes.
The current ease of obtaining thousands of molecular markers challenges the notion that full phylogenetic concordance, as proposed by phylogenetic species concepts, is a requirement for defining species delimitations. Indeed, the presence of genomic islands of divergence, which may be the cause, or in some cases the consequence, of speciation, precludes concordance. Here, we explore this issue using thousands of RAD markers on two sister species of surgeonfishes (Teleostei: Acanthuridae), Zebrasoma flavescens and Z. scopas, and several populations within each species. Species are readily distinguished based on their colors (solid yellow and solid brown, respectively), yet populations and species are neither distinguishable using mitochondrial markers (cytochrome c oxidase 1), nor using 5193 SNPs (pairwise Φst = 0.034). In contrast, when using outlier loci, some of them presumably under selection, species delimitations, and strong population structure follow recognized taxonomic positions (pairwise Φst = 0.326). Species and population delimitation differences based on neutral and selected markers are likely due to local adaptation, thus being consistent with the idea that these genomic islands of divergence arose as a consequence of isolation. These findings, which are not unique, raise the question of a potentially important pathway of divergence based on local adaptation that is only evident when looking at thousands of loci
Effects of Natal Departure and Water Level on Survival of Juvenile Snail Kites (\u3ci\u3eRostrhamus sociabilis\u3c/i\u3e) in Florida
Survival rate from fledging to breeding, or juvenile survival, is an important source of variation in lifetime reproductive success in birds. Therefore, determining the relation-ship between juvenile survival and environmental factors is essential to understanding fitness consequences of reproduction in many populations. With increases in density of individuals and depletion of food resources, quality of most habitats deteriorates during the breeding season. Individuals respond by dispersing in search of food resources. Therefore, to understand the influence of environmental factors on juvenile survival, it is also necessary to know how natal dispersal influences survival of juveniles. We examined effects of various environmental factors and natal dispersal behavior on juvenile survival of endangered Snail Kites (Rostrhamus sociabilis) in central and southern Florida, using a generalized estimating equations (GEEs) approach and model selection criteria. Our results suggested yearly effects and an influence of age and monthly minimum hydrologic levels on juvenile Snail Kite survival. Yearly variation in juvenile survival has been reported by other studies, and other reproductive components of Snail Kites also exhibit such variation. Age differences in juvenile survival have also been seen in other species during the juvenile period. Our results demonstrate a positive relationship between water levels and juvenile survival. We suggest that this is not a direct linear relationship, such that higher water means higher juvenile survival. The juvenile period is concurrent with onset of the wet season in the ecosystem we studied, and rainfall increases as juveniles age. For management purposes, we believe that inferences suggesting increasing water levels during the fledging period will increase juvenile survival may have short-term benefits but lead to long-term declines in prey abundance and possibly wetland vegetation structure
Impacts of agricultural land use on biological integrity: a causal analysis
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/116919/1/eap20112183128.pd
Ten myths about character, virtue and virtue education – plus three well-founded misgivings
Initiatives to cultivate character and virtue in moral education at school continue to provoke sceptical responses. Most of those echo familiar misgivings about the notions of character, virtue and education in virtue – as unclear, redundant, old-fashioned, religious, paternalistic, anti-democratic, conservative, individualistic, relative and situation dependent. I expose those misgivings as ‘myths’, while at the same time acknowledging three better-founded historical, methodological and practical concerns about the notions in question
Smoking Enhances Risk for New External Genital Warts in Men
Repeat episodes of HPV-related external genital warts reflect recurring or new infections. No study before has been sufficiently powered to delineate how tobacco use, prior history of EGWs and HIV infection affect the risk for new EGWs. Behavioral, laboratory and examination data for 2,835 Multicenter AIDS Cohort Study participants examined at 21,519 semi-annual visits were evaluated. Fourteen percent (391/2835) of men reported or were diagnosed with EGWs at 3% (675/21,519) of study visits. Multivariate analyses showed smoking, prior episodes of EGWs, HIV infection and CD4+ T-lymphocyte count among the infected, each differentially influenced the risk for new EGWs
The Proportion of Snail Kites Attempting to Breed and the Number of Breeding Attempts per Year in Florida
During the breeding season of 1995 we monitored the proportion of adult and subadult Snail Kites (Rostrhamus sociabilis) attempting to breed and the number of breeding attempts using radio telemetry. Our sample consisted of 23 adults (14 females, 9 males) and 9 subadults for which we had data over the entire breeding season. All adults attempted to breed at least once with an observed average of 1.4 (± 0.6 SD) breeding attempts per individual. In contrast, only 3 (33%) of the subadults attempted to breed. Of the adults, 15 (65%) made one breeding attempt, 7 (30%) made two breeding attempts,and 1 (4%) attempted three times. Only one bird (4%) successfully raised two broods. Our data are consistent with previous reports that \u3e1 breeding attempt by Snail Kites in Florida is common during some years, although our estimate for 1995 was lower han previously reported estimates. A combination of our estimation procedures, definitions of a breeding attempt, and annual variability of this parameter probably account for the disparity between our data and previous reports
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