344 research outputs found

    B. F. Gentry to W. R. Gentry (12 July 186?)

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    Benjamin discussing food, general conditions and their movements around northern Mississippi, near Tupelo, Ripley and Saltillo.https://egrove.olemiss.edu/ciwar_corresp/1382/thumbnail.jp

    B. F. Gentry to W. R. and Mariah Gentry (29 October 1862)

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    Benjamin discussing hearing of other battles, his marching in poor weather and word from home. Also provides a list of desired clothing from his mother.https://egrove.olemiss.edu/ciwar_corresp/1379/thumbnail.jp

    B. F. Gentry to W. R. and Mariah Gentry (April 1864)

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    Benjamin mentions rumors of fighting in Chattanooga, TN., and speculates on Virginia and North Carolina; mentions his regiment\u27s movements and discusses hearing of life at home.https://egrove.olemiss.edu/ciwar_corresp/1381/thumbnail.jp

    B. F. Gentry to W. R. and Mariah Gentry (22 August 1863)

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    Benjamin discusses food quality and requests money to buy supplies. Also passes along word to his family and servants.https://egrove.olemiss.edu/ciwar_corresp/1378/thumbnail.jp

    Numerical simulation of colloidal dispersion filtration: description of critical flux and comparison with experimental results

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    During filtration via membrane processes, colloids accumulate at the porous surface leading to fouling phenomena. In this study, a rigorous simulation of momentum and mass transfer using CFD modelling has been developed to describe such an accumulation during cross flow filtration. These simulations integrate detailed modeling of physicochemical properties specific to colloidal dispersions (because of the surface interactions (repulsive and attractive) occurring between the colloids particles). These interactions are accounted for via the experimental variation of the colloidal osmotic pressure with volume fraction (associated with a variation in the diffusion coefficient) which are fitted by a relationship integrated into the CFD code. It contains a description of the colloidal phase transition leading to the formation of a condensed phase (deposit or gel layer) from the accumulated dispersed phase (concentration polarization). It is then possible to determine the critical flux which separates filtration conditions below which mass accumulation is reversible (in the dispersed phase) and above which it is irreversible (in the condensed phase). The computed value of critical flux is compared with that determined experimentally for a dispersion of latex particles

    Connecting With Clients in Later Life: The Use of Telebehavioral Health to Address Older Adults’ Mental Health Needs

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    Telebehavioral health offers a unique opportunity to expand access to mental health services for older clients by addressing systemic barriers that often render mental health care inaccessible in later life. Although health interventions facilitated by technology, including telebehavioral health approaches, proliferated at the start of the COVID-19 pandemic, little guidance exists for counselors seeking to provide such services to clients in later life. In this manuscript, we describe challenges accessing mental health services, how telebehavioral health services can address these barriers, and practical consideration for delivering telebehavioral health approaches for counselors who work with older clients

    Computational Microwave Imaging Using 3D Printed Conductive Polymer Frequency-Diverse Metasurface Antennas

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    A frequency-diverse computational imaging system synthesized using three-dimensional (3D) printed frequency-diverse metasurface antennas is demonstrated. The 3D fabrication of the antennas is achieved using a combination of PolyLactic Acid (PLA) polymer material and conductive polymer material (Electrifi), circumventing the requirement for expensive and time-consuming conventional fabrication techniques, such as machine milling, photolithography and laser-etching. Using the 3D printed frequency- diverse metasurface antennas, a composite aperture is designed and simulated for imaging in the K-band frequency regime (17.5-26.5 GHz). The frequency-diverse system is capable of imaging by means of a simple frequency-sweep in an-all electronic manner, avoiding mechanical scanning and active circuit components. Using the synthesized system, microwave imaging of objects is achieved at the diffraction limit. It is also demonstrated that the conductivity of the Electrifi polymer material significantly affects the performance of the 3D printed antennas and therefore is a critical factor governing the fidelity of the reconstructed images.Comment: Original manuscript as submitted to IET Microwaves, Antennas & Propagation (2017). 17 pages, 8 figure

    Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis.

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    Miner1 is a redox-active 2Fe2S cluster protein. Mutations in Miner1 result in Wolfram Syndrome, a metabolic disease associated with diabetes, blindness, deafness, and a shortened lifespan. Embryonic fibroblasts from Miner1(-/-) mice displayed ER stress and showed hallmarks of the unfolded protein response. In addition, loss of Miner1 caused a depletion of ER Ca(2+) stores, a dramatic increase in mitochondrial Ca(2+) load, increased reactive oxygen and nitrogen species, an increase in the GSSG/GSH and NAD(+)/NADH ratios, and an increase in the ADP/ATP ratio consistent with enhanced ATP utilization. Furthermore, mitochondria in fibroblasts lacking Miner1 displayed ultrastructural alterations, such as increased cristae density and punctate morphology, and an increase in O2 consumption. Treatment with the sulphydryl anti-oxidant N-acetylcysteine reversed the abnormalities in the Miner1 deficient cells, suggesting that sulphydryl reducing agents should be explored as a treatment for this rare genetic disease

    The tRNA Synthetase Paralog PoxA Modifies Elongation Factor-P with (R)-β-lysine

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    The lysyl-tRNA synthetase paralog PoxA modifies elongation factor P (EF-P) with α-lysine at low efficiency. Cell-free extracts containing non–α-lysine substrates of PoxA modified EF-P with a change in mass consistent with addition of β-lysine, a substrate also predicted by genomic analyses. EF-P was efficiently functionally modified with (R)-β-lysine but not (S)-β-lysine or genetically encoded α-amino acids, indicating that PoxA has evolved an activity orthogonal to that of the canonical aminoacyl-tRNA synthetases
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