Saprolegnia diclina IIIA and S. parasitica employ different infection strategies when colonizing eggs of Atlantic salmon, Salmo salar L.

Acknowledgements The work has been funded by the European Commission through the EU Marie Curie ITN project SAPRO (238550) (MMS, AW). We would also like to acknowledge support from the BBSRC and the University of Aberdeen (PvW) and Landcatch and AquaGen for providing salmon eggs. Elin Rolen's assistance with sequencing of the strains is highly appreciated.Peer reviewedPublisher PD

Divergent expression of claudin -1, -3, -4, -5 and -7 in developing human lung

<p>Abstract</p> <p>Background</p> <p>Claudins are the main components of tight junctions, structures which are associated with cell polarity and permeability. The aim of this study was to analyze the expression of claudins 1, 3, 4, 5, and 7 in developing human lung tissues from 12 to 40 weeks of gestation.</p> <p>Methods</p> <p>47 cases were analyzed by immunohistochemisty for claudins 1, 3, 4, 5 and 7. 23 cases were also investigated by quantitative RT-PCR for claudin-1, -3 and -4.</p> <p>Results</p> <p>Claudin-1 was expressed in epithelium of bronchi and large bronchioles from week 12 onwards but it was not detected in epithelium of developing alveoli. Claudin-3, -4 and -7 were strongly expressed in bronchial epithelium from week 12 to week 40, and they were also expressed in alveoli from week 16 to week 40. Claudin-5 was expressed strongly during all periods in endothelial cells. It was expressed also in epithelium of bronchi from week 12 to week 40, and in alveoli during the canalicular period. RT-PCR analyses revealed detectable amounts of RNAs for claudins 1, 3 and 4 in all cases studied.</p> <p>Conclusion</p> <p>Claudin-1, -3, -4, -5, and -7 are expressed in developing human lung from week 12 to week 40 with distinct locations and in divergent quantities. The expression of claudin-1 was restricted to the bronchial epithelium, whereas claudin-3, -4 and -7 were positive also in alveolar epithelium as well as in the bronchial epithelium. All claudins studied are linked to the development of airways, whereas claudin-3, -4, -5 and -7, but not claudin-1, are involved in the development of acinus and the differentiation of alveolar epithelial cells.</p

Multi-frequency VLBA study of the blazar S5 0716+714 during the active state in 2004: I. Inner jet kinematics

We observed the blazar \object{0716+714} with the VLBA during its active state in 2003-2004. In this paper we discuss multi-frequency analysis of the inner jet (first 1 mas) kinematics. The unprecedentedly dense time sampling allows us to trace jet components without misidentification and to calculate the component speeds with good accuracy. In the smooth superluminal jet we were able to identify and track three components over time moving outwards with relatively high apparent superluminal speeds (8.5-19.4 $c$), which contradicts the hypothesis of a stationary oscillating jet in this source. Component ejections occur at a relatively high rate (once in two months), and they are accompanied by mm-continuum outbursts. Superluminal jet components move along wiggling trajectories, which is an indication of actual helical motion. Fast proper motion and rapid decay of the components suggest that this source should be observed with the VLBI at a rate of at least once in one or two months in order to trace superluminal jet components without confusion.Comment: 4 pages, 3 figures, Astronomy & Astrophysics Letter, language corrections adde

Partner choice and timing of first marriage among the children of immigrants in Norway and Sweden

Using population register data from Norway (n = 209,532) and Sweden (n = 592,491), this study addressed the relationship between partner choice and the timing of first marriage. We considered all migrant-background individuals born between 1972 and 1989 who were either native-born or who immigrated prior to age 18, relative to 10% random samples of the majority populations. The results demonstrate that marital timing patterns of migrant background individuals who married exogamously (that is, with a majority-background spouse or across their global region of origin) were more similar to the majority populations than among those who married endogamously (that is, with another migrant-background individual originating in the same global region). However, among immigrant-background individuals who endogamously married, there was evidence of a shift toward the Scandinavian pattern of later marriage across generations. Taken together the results provide an important starting point for investigations into the family life-courses and social position of children of immigrants in Europe, an increasingly large population subgroup currently entering family formation ages. Keywords Assortative mating, children of immigrants, endogamy, exogamy, marriage timing, second generationacceptedVersio

Probing Anomalous Wtb Coupling via Single Top Production at TeV Energy γ\gamma e Colliders

Results of complete tree level calculations of the single top production reaction $\gamma e \to \nu \bar{t} b$ at the Next Linear Collider, including the contribution of anomalous operators to the Wtb coupling are presented. The sensitivity for probing the structure of the Wtb coupling in a model independent way is analyzed and found to be significantly higher than for comparable measurements at the Tevatron.Comment: 10 Latex pages including 1 ps-figure and 3 eps-figure