Modeling the Influence of Energy and Climate Megatrends on Future Costs and Benefits of Marsh Creation in the Mississippi Delta

Over 25% of Mississippi delta (MRDP) wetlands were lost over the past century. There is currently a major effort to restore the MRDP focused on a 50-year time horizon, a period during which the energy system and climate will change dramatically. I modeled hydraulic dredging to sustain marsh from 2016-2066 and 2016-2100 under a range of scenarios for sea level rise, energy price, and management regimes. A marsh elevation model was calibrated to data from MRDP marshes. I developed a model to simulate dredging costs based on the price of crude oil and a project efficiency factor. Crude oil prices were projected using forecasts from global energy models. The costs to sustain marsh between 2016 and 2100 changed from $128,000 ha-1 in the no change scenario to ~$1,010,000 ha-1 in the worst-case scenario in sea level rise and energy price, an ~8-fold increase. Increasing suspended sediment load raised created marsh lifespan and decreased long term dredging costs. Created marsh lifespan changed nonlinearly with dredging fill elevation and suspended sediment level. Costs and benefits of marsh creation can be optimized by adjusting dredging fill elevations based on the local sediment regime. Regardless of management scenario, sustaining the MRDP with hydraulic dredging suffered declining returns on investment due to the convergence of energy and climate. Marsh creation will likely become unaffordable in the mid to late 21st century, especially if river sediment diversions are not constructed before 2030. Planners must take into consideration coupled energy and climate scenarios for long-term risk assessments and adjust restoration goals accordingly

Evaluating trade-offs of a large, infrequent sediment diversion for restoration of a forested wetland in the Mississippi delta

© 2018 Elsevier Ltd Flood control levees cut off the supply of sediment to Mississippi delta coastal wetlands, and contribute to putting much of the delta on a trajectory for continued submergence in the 21st century. River sediment diversions have been proposed as a method to provide a sustainable supply of sediment to the delta, but the frequency and magnitude of these diversions needs further assessment. Previous studies suggested operating river sediment diversions based on the size and frequency of natural crevasse events, which were large (\u3e5000 m3/s) and infrequent (active \u3c once a year) in the last naturally active delta. This study builds on these previous works by quantitatively assessing tradeoffs for a large, infrequent diversion into the forested wetlands of the Maurepas swamp. Land building was estimated for several diversion sizes and years inactive using a delta progradation model. A benefit-cost analysis (BCA) combined model land building results with an ecosystem service valuation and estimated costs. Results demonstrated that land building is proportional to diversion size and inversely proportional to years inactive. Because benefits were assumed to scale linearly with land gain, and costs increase with diversion size, there are disadvantages to operating large diversions less often, compared to smaller diversions more often for the immediate project area. Literature suggests that infrequent operation would provide additional gains (through increased benefits and reduced ecosystem service costs) to the broader Lake Maurepas-Pontchartrain-Borgne ecosystem. Future research should incorporate these additional effects into this type of BCA, to see if this changes the outcome for large, infrequent diversions

Potential for soil legacy phosphorus release from restored riparian wetlands within an agricultural landscape

Wetlands are valuable ecosystems because they are highly productive, support a wide range of wildlife, and serve as hotspots for biogeochemical cycling. Historically, vast areas of wetlands in the United States (US) were drained and converted to agriculture. Efforts are currently underway to restore wetland and floodplain functioning across the US and elsewhere. Re-wetting historically drained and farmed soils can potentially liberate legacy phosphorus (P) to surface waters as soluble reactive P (SRP), offsetting P retained by sedimentation during floods. A better understanding of the controls on SRP release is needed to estimate net P retention in these settings. Soil P saturation ratio (PSR) and soil P storage capacity (SPSC) are two proxies for SRP runoff risk that have shown promise for characterizing restored wetlands but require further testing. In this study, we examined soils at 42 riparian sites ranging from active farms to mature wetlands in the Vermont portion of the Lake Champlain Basin (USA), where phosphorus load reduction is a critical goal to achieve in-lake water quality targets. We additionally quantified potential SRP release to overlying water using intact soil cores from 20 plots spanning 14 sites. Final SRP concentrations in intact cores spanned two orders of magnitude and were predicted well by SPSC and PSR. SRP release was greatest at more recently and frequently farmed sites. Several soil properties, including PSR and SPSC, were correlated with farming frequency and time since farming, indicating that SRP release could be mapped using existing geodata for soils, hydrology and land use. Our findings confirm that soil SRP release during flooding needs to be considered in estimates of net P balance for restored riparian wetlands in agricultural landscapes.Fil: Wiegman, Adrian R. H.. United States Department of Agriculture. Agriculture Research Service; Estados Unidos. University of Vermont; Estados UnidosFil: Myers, G. Harrison. University of Vermont; Estados UnidosFil: Augustin, Isabelle C.. University of Vermont; Estados UnidosFil: Kubow, Marcos L.. University of Vermont; Estados UnidosFil: Fein-Cole, Maya J.. University of Vermont; Estados UnidosFil: Perillo, Vanesa Liliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto Argentino de Oceanografía. Universidad Nacional del Sur. Instituto Argentino de Oceanografía; Argentina. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia; Argentina. University of Vermont; Estados UnidosFil: Ross, Donald S.. University of Vermont; Estados UnidosFil: Diehl, Rebecca M.. University of Vermont; Estados UnidosFil: Underwood, Kristen L.. University of Vermont; Estados UnidosFil: Bowden, William B.. University of Vermont; Estados UnidosFil: Roy, Eric D.. University of Vermont; Estados Unido

Strategies to improve radiotherapy with targeted drugs

Item does not contain fulltextRadiotherapy is used to treat approximately 50% of all cancer patients, with varying success. The dose of ionizing radiation that can be given to the tumour is determined by the sensitivity of the surrounding normal tissues. Strategies to improve radiotherapy therefore aim to increase the effect on the tumour or to decrease the effects on normal tissues. These aims must be achieved without sensitizing the normal tissues in the first approach and without protecting the tumour in the second approach. Two factors have made such approaches feasible: namely, an improved understanding of the molecular response of cells and tissues to ionizing radiation and a new appreciation of the exploitable genetic alterations in tumours. These have led to the development of treatments combining pharmacological interventions with ionizing radiation that more specifically target either tumour or normal tissue, leading to improvements in efficacy