O papel da mãe no tratamento de criança com recidiva de câncer

O câncer no Brasil representa a primeira causa de morte (8% do total) por doença entre crianças e adolescentes de 1 a 19 anos, segundo o Instituto Nacional de Câncer [1]. Ao mesmo tempo em que pode haver boa chance de sobrevivência quando a doença é detectada precocemente, de outra parte a recidiva do câncer é impactante. Nesse momento de recomeço, a mãe do paciente possui papel de destaque, pois sabe-se que os indivíduos envolvidos nesse contexto são vulneráveis e que prevalecem sentimentos de falta de controle da situação, perplexidade e ansiedade. Percebe-se o caráter multidisciplinar (da psicologia, da bioética, da saúde) e pluralista do assunto, tal como preceituado no artigo 2° da Declaração Universal sobre Bioética e Direitos Humanos, da UNESCO. Método: a pesquisa proposta tem como fundamento a análise do papel da mãe no tratamento da criança com recidiva de câncer. Trata-se de um ensaio reflexivo sobre o tema, à luz da Declaração Universal sobre Bioética e Direitos Humanos, da UNESCO

Transmon in a semi-infinite high-impedance transmission line: Appearance of cavity modes and Rabi oscillations

In this paper, we investigate the dynamics of a single superconducting artificial atom capacitively coupled to a transmission line with a characteristic impedance comparable to or larger than the quantum resistance. In this regime, microwaves are reflected from the atom also at frequencies far from the atom\u27s transition frequency. Adding a single mirror in the transmission line then creates cavity modes between the atom and the mirror. Investigating the spontaneous emission from the atom, we then find Rabi oscillations, where the energy oscillates between the atom and one of the cavity modes

IMPACTS OF COMMINGLING CATTLE FROM DIFFERENT SOURCES ON THEIR PHYSIOLOGICAL, HEALTH, AND PERFORMANCE RESPONSES DURING FEEDLOT RECEIVING

This experiment compared physiological, health, and performance responses of beef heifers assigned to different commingling schemes (1, 2, or 4 sources/pen) during a 56-d feedlot receiving period. Ninety-six recently weaned Angus-influenced heifers were obtained from an auction facility. Heifers originated from 4 cow-calf ranches and were reared in the same herd within each ranch since birth. Heifers were loaded into 2 livestock trailers at the auction yard (2 sources/trailer; d -2), arranged in 2 sections of each trailer according to source, and transported for 10 h to stimulate the stress of a long-haul. Heifers were not mixed with cohorts from other sources prior to and at the auction yard. Upon arrival (d -2), shrunk body weight (BW) was recorded and heifers were maintained in 4 paddocks by source with ad libitum access to a complete starter feed and water for 36 h. On d 0, heifers were ranked by source and shrunk BW and allocated to 1 of 24 drylot pens (4 heifers/pen) containing: 1) heifers from a single source (1SRC, n = 8), 2) heifers from 2 sources (2SRC, n = 8), or 3) heifers from 4 sources (4SRC, n = 8). From d 0 to 55, heifers had free-choice access to the complete starter feed and water. Heifers were assessed daily for symptoms of bovine respiratory disease (BRD), and feed intake was recorded from each pen daily. Blood samples were collected on d 0, 6, 13, 27, 41, and 55, and shrunk BW (after 16 h of water and feed withdrawal) was recorded on d 56 for average daily gain (ADG). No treatment differences were noted (P ≥ 0.56) for heifer ADG (mean ± SE = 0.853 ± 0.043 kg/d), final shrunk BW, feed intake, and feed efficiency. No treatment differences were noted (P ≥ 0.27) for plasma concentrations of cortisol and haptoglobin, and serum concentrations of antibodies against BRD viruses and Mannheimia haemolytica. No treatment differences were noted (P ≥ 0.17) for incidence of BRD (mean ± SE = 59.3 ± 5.0 %) or mortality. The proportion of heifers diagnosed with BRD that required three antimicrobial treatments to regain health increased linearly (P = 0.03) according to the number of sources (0.0, 12.3, and 20.8% of 1SRC, 2SRC, and 4SRC heifers, respectively; SEM = 7.0). Hence, commingling heifers from different sources did not impact performance, physiological responses, and BRD incidence during a 56-d receiving period, although recurrence of BRD after the second antimicrobial treatment increased according to commingling level

Methods of editing cloud and atmospheric layer affected pixels from satellite data

The location and migration of cloud, land and water features were examined in spectral space (reflective VIS vs. emissive IR). Daytime HCMM data showed two distinct types of cloud affected pixels in the south Texas test area. High altitude cirrus and/or cirrostratus and "subvisible cirrus" (SCi) reflected the same or only slightly more than land features. In the emissive band, the digital counts ranged from 1 to over 75 and overlapped land features. Pixels consisting of cumulus clouds, or of mixed cumulus and landscape, clustered in a different area of spectral space than the high altitude cloud pixels. Cumulus affected pixels were more reflective than land and water pixels. In August the high altitude clouds and SCi were more emissive than similar clouds were in July. Four-channel TIROS-N data were examined with the objective of developing a multispectral screening technique for removing SCi contaminated data

Antagonistic Autoantibodies to Insulin-Like Growth Factor-1 Receptor Associate with Poor Physical Strength

Natural autoantibodies to the IGF1 receptor (IGF1R-aAb) have been described in relation to Graves' ophthalmopathy. Other physiological roles of natural IGF1R-aAb are not known. We hypothesized that IGF1R-aAb may be related to muscle development. Serum samples (n = 408) from young overweight subjects (n = 143) were collected during a lifestyle intervention study. Anthropometric parameters, along with leptin, IGF1 and IGF1R-aAb concentrations, were analyzed, and the subjects were categorized into positive or negative for IGF1R-aAb. Eleven out of 143 subjects (7.7%) were positive for IGF1R-aAb. Identified IGF1R-aAb were molecularly characterized and showed antagonistic activity in vitro impairing IGF1-mediated IGF1R activation. Mean body weight, height or age were similar between IGF1R-aAb-positive and -negative subjects, but IGF1 concentrations differed. Jumping ability, as well as right and left handgrip strengths, were lower in the IGF1R-aAb-positive as compared to the IGF1R-aAb-negative subjects. We conclude that natural IGF1R-aAb are detectable in apparently healthy subjects and are capable of antagonizing IGF1-dependent IGF1R activation. Moreover, the presence of IGF1R-aAb is associated with poor physical strength. Although the causality of this association is unclear, the data imply a potential influence of IGF1R autoimmunity on muscle development