A sequential linear discriminant analysis program for geological and remotely-sensed data

Sequential linear discriminant analysis program for geological and remotely sensed dat

Variance of some selected attributes in granitic rocks

Variance in selected attributes in granit

Statistical evaluation of the composition, physical properties, and surface configuration of terrestrial test sites and their correlation with remotely sensed data Final report

Utilizing spatial filtering for analyzing structural configuration of Michigan Basin for application to remote sensin

Enigmas in assessing the composition of a rock unit - a case history based on the Malsburg Granite, southwest Germany

Critical sampling problems for assessment of composition and variability of rock formation

A surface-fitting program for areally- distributed data from the earth sciences and remote sensing

Fortran II program for analysis of data from earth sciences and remote sensin

Structural Origins of Misfolding Propensity in the Platelet Adhesive Von Willebrand Factor A1 Domain

AbstractThe von Willebrand factor (VWF) A1 and A3 domains are structurally isomorphic yet exhibit distinct mechanisms of unfolding. The A1 domain, responsible for platelet adhesion to VWF in hemostasis, unfolds through a molten globule intermediate in an apparent three-state mechanism, while A3 unfolds by a classical two-state mechanism. Inspection of the sequences or structures alone does not elucidate the source of this thermodynamic conundrum; however, the three-state character of the A1 domain suggests that it has more than one cooperative substructure yielding two separate unfolding transitions not present in A3. We investigate the extent to which structural elements contributing to intermediate conformations can be identified using a residue-specific implementation of the structure-energy-equivalence-of-domains algorithm (SEED), which parses proteins of known structure into their constituent thermodynamically cooperative components using protein-group-specific, transfer free energies. The structural elements computed to contribute to the non-two-state character coincide with regions where Von Willebrand disease mutations induce misfolded molten globule conformations of the A1 domain. This suggests a mechanism for the regulation of rheological platelet adhesion to A1 based on cooperative flexibility of the α2 and α3 helices flanking the platelet GPIbα receptor binding interface

The NASA Ames Research Center one- and two-dimensional stratospheric models. Part 2: The two-dimensional model

The two-dimensional model of stratospheric constituents is presented in detail. The derivation of pertinent transport parameters and the numerical solution of the species continuity equations, including a technique for treating the stiff differential equations that represent the chemical kinetic terms, and appropriate methods for simulating the diurnal variations of the solar zenith angle and species concentrations are discussed. Predicted distributions of tracer constituents (ozone, carbon 14, nitric acid) are compared with observed distributions

The Impact of Information Technology Outsourcing on Firm Profitability Measures

Some researchers have concluded that outsourcing of information technology (IT) provides benefits to firms including cost advantages, economies of scale and allowing more of a focus on core competencies. This paper attempts to determine if these benefits actually exist by comparing three financial measures, return on equity (ROE), return on assets (ROA) and profit margin, affirms that have varying levels of outsourcing. To empirically test for the existence of a difference between firms that outsource differing amounts of IT spending, data from 104 companies was gathered. Analysis of variance was selected as the primary statistical tool to test the relationship between the level of outsourcing and the profitability measures. The results of this study lead to the conclusion that there is not a significant difference between the amounts of IT outsourcing companies perform and any of the profitability measures used during the sample period. Further discussion continues related to the implications of the results