Cooper: \u3cem\u3eThe Lawyer and Administrative Agencies\u3c/em\u3e

A Review of The Lawyer and Administrative Agencies. By Frank E. Cooper

A World of Peace and Justice Under the Rule of Law: From Nuremberg to the International Criminal Court

The genesis of the trial of the major German war criminals at the end of World War II was the Moscow Conference of October, 1943, at the conclusion of which, a statement was signed by President Roosevelt, Prime Minister Churchill, and Premier Stalin declaring the determination of the three powers to hold Germans individually responsible for crimes committed by them in the course of the war. The statement did not declare whether such offenders would be punished by executive action or pursuant to the judicial process. In Britain, Lord Chancellor Simon and Prime Minister Churchill were of the view that major war criminals should be disposed of by executive action. This view was echoed in the United States by Secretary of the Treasury Morganthau, who proposed to President Roosevelt that German arch criminals be shot upon capture and identification. Secretary Morganthau was opposed in the Cabinet by Secretary of War Henry L. Stimpson who believed that leading Nazis should be brought to trial before an international military tribunal. Stimpson’s views ultimately prevailed and a memorandum recommending a trial was prepared for the use of President Roosevelt at the three-power Yalta Conference in February 1945. The memorandum stated that condemnation of German war criminals after a trial would command maximum public support and receive the respect of history and it noted that use of the judicial method would make an authentic historic record of Nazi crimes

Diffusion MR Characteristics Following Concurrent Radiochemotherapy Predicts Progression-Free and Overall Survival in Newly Diagnosed Glioblastoma.

The standard of care for newly diagnosed glioblastoma (GBM) is surgery, then radiotherapy (RT) with concurrent temozolomide (TMZ), followed by adjuvant TMZ. We hypothesized patients with low diffusivity measured using apparent diffusion coefficient (ADC) histogram analysis evaluated after RT+TMZ, prior to adjuvant TMZ, would have a significantly shorter progression-free (PFS) and overall survival (OS). To test this hypothesis we evaluated 120 patients with newly diagnosed GBM receiving RT+TMZ followed by adjuvant TMZ. MRI was performed after completion of RT+TMZ, prior to initiation of adjuvant TMZ. A double Gaussian mixed model was used to describe the ADC histograms within the enhancing tumor, where ADCL and ADCH were defined as the mean ADC value of the lower and higher Gaussian distribution, respectively. An ADCL value of 1.0 um2/ms and ADCH value of 1.6 um2/ms were used to stratify patients into high and low risk categories. Results suggest patients with low ADCL had significantly shorter PFS (Cox Hazard Ratio = 0.12, P = 0.0006). OS was significantly shorter with low ADCL tumors, showing a median OS of 407 vs. 644 days (Cox Hazard Ratio = 0.31, P = 0.047). ADCH was not predictive of PFS or OS when accounting for age and ADCL. In summary, newly diagnosed glioblastoma patients with low ADCL after completion of RT+TMZ are likely to progress and die earlier than patients with higher ADCL. Results suggest ADC histogram analysis may be useful for patient risk stratification following completion of RT+TMZ

Pre-main sequence stars in the stellar association N11 in the Large Magellanic Cloud

Magellanic Clouds are of extreme importance to the study of the star formation process in low metallicity environments. In this paper we report on the discovery of pre-main sequence candidates and young embedded stellar objects in N11 located in the Large Magellanic Cloud to cast light on the star formation scenario. We would like to remind that this comparison is complicated by the presence of a large age dispersion detected in the fields. Deep archive HST/ACS photometry is used to derive color-magnitude diagrams of the associations in N~11 and of the foreground field population. These data are complemented by archive IR Spitzer data which allow the detection of young embedded stellar objects. The spatial distribution of the pre-main sequence candidates and young embedded stellar objects is compared with literature data observed at different wavelengths, such as H$_{\alpha}$ and CO maps, and with the distribution of OB and Herbig Ae/Be stars. The degree of clustering is derived using the Minimal Spanning Tree method and the two point correlation function to get insights about the formation process. A large population of pre-main sequence candidates is found in N11. Their masses are in the range of 1.3-2 MSun for ages from 2 to 10 Myr. Young embedded stellar objects having ages of 0.1-1 Myr are found to be intermixed with the candidate pre-main sequence stars. The spatial distribution of the stars shows that this region is the product of clustered star formation. No significant difference is found in the clustering degree of young blue main sequence stars and faint pre-main sequence candidates, suggesting that they might be part of the same formation process. The data suggest that the star formation in the region is a long-lasting process where stars from 0.1 to 10 Myr are widely distributed.Comment: 18 pages, 21 figures, accepted for publication in A&

Assessment of Surgical Procedural Time, Pedicle Screw Accuracy, and Clinician Radiation Exposure of a Novel Robotic Navigation System Compared With Conventional Open and Percutaneous Freehand Techniques: A Cadaveric Investigation

STUDY DESIGN: Cadaveric study. OBJECTIVE: To evaluate accuracy, radiation exposure, and surgical time of a new robotic-assisted navigation (RAN) platform compared with freehand techniques in conventional open and percutaneous procedures. METHODS: Ten board-certified surgeons inserted 16 pedicle screws at T10-L5 (n = 40 per technique) in 10 human cadaveric torsos. Pedicle screws were inserted with (1) conventional MIS technique (L2-L5, patient left pedicles), (2) MIS RAN (L2-L5, patient right pedicles), (3) conventional open technique (T10-L1, patient left pedicles), and (4) open RAN (T10-L1, patient right pedicles). Output included (1) operative time, (2) number of fluoroscopic images, and (3) screw accuracy. RESULTS: In the MIS group, compared with the freehand technique, RAN allowed for use of larger screws (diameter: 6.6 ± 0.6 mm vs 6.3 ± 0.5 mm; length: 50.3 ± 4.1 mm vs 46.9 ± 3.5 mm), decreased the number of breaches \u3e2 mm (0 vs 7), fewer fluoroscopic images (0 ± 0 vs 108.3 ± 30.9), and surgical procedure time per screw (3.6 ± 0.4 minutes vs 7.6 ± 2.0 minutes) (all CONCLUSION: RAN significantly improved accuracy and decreased radiation exposure in comparison to freehand techniques in both conventional open and percutaneous surgical procedures in cadavers. RAN significantly increased setup time compared with both conventional procedures