Fourlined Plant Bug (Hemiptera: Miridae), a Reappraisal: Life History, Host Plants, and Plant Response to Feeding

Phenology of the fourlined plant bug, Poecilocapsus lineatus, is presented for southcen- tral Pennsylvania; life history and habits are re-examined. Although breeding was previously thought to occur only on woody plants, we found that nymphs develop on numerous herbs. An extensive list of hosts, more than 250 species in 57 families, is compiled from the literature and the authors\u27 observations; preferences are noted for plants in the Labiatae, Solanaceae, and Compositae. Damage consists of lesions on foliage, the size and shape of the spots varying with leaf texture, pubescence, and venation. Plant response to feeding is immediately visible, the lesions seeming to appear simultaneously with insertion of the bug\u27s stylets. Histolysis of plant tissues, the most rapid response to mind feeding yet reported, is attributed to a potent lipid enzyme whose active constituents are under investigation

John Robert Eyer: Entomological Work in Pennsylvania and Lists of Publications

(excerpt) John Robert Eyer died at Carlsbad, New Mexico, on January 30, 1976. J. G. Watts and W. A. Iselin (1976), his former colleagues in the Department of Botany and Entomology at New Mexico State University, Las Cruces, wrote an obituary and quite naturally focused on Eyer\u27s work at the University\u27s Agricultural Experiment Station. Since Dr. Eyer\u27s first positions in entomology were in Pennsylvania, we have prepared this biographical sketch to preserve the record of his early accomplishments

LILAC 2023: An audio-visual report

The authors work together at Middlesex University as subject liaison librarians and what follows is a report on the LILAC 2023 conference at the University of Cambridge. The authors chose to combine their reflections in a collaborative report, and when considering a focus for this, it was noted that a number of sessions incorporating non-traditional methods and formats, such as podcasting, cartooning and audiobooks, had attracted the attention of the authors. Therefore, the theme of audio-visual learning is the focus for this conference report. Moreover, the authors were keen for the format of the output to align with the content, so rather than submitting a written report, what follows is an audio-visual report comprising a discussion of conference experiences, a photo diary and an artwork, where the authors reflect on their impressions, highlights and key takeaways from the event

Drug Predictive Cues Activate Aversion-Sensitive Striatal Neurons That Encode Drug Seeking

Drug-associated cues have profound effects on an addict’s emotional state and drug-seeking behavior. Although this influence must involve the motivational neural system that initiates and encodes the drug-seeking act, surprisingly little is known about the nature of such physiological events and their motivational consequences. Three experiments investigated the effect of a cocaine-predictive stimulus on dopamine signaling, neuronal activity, and reinstatement of cocaine seeking. In all experiments, rats were divided into two groups (paired and unpaired), and trained to self-administer cocaine in the presence of a tone that signaled the immediate availability of the drug. For rats in the paired group, self-administration sessions were preceded by a taste cue that signaled delayed drug availability. Assessments of hedonic responses indicated that this delay cue became aversive during training. Both the self-administration behavior and the immediate cue were subsequently extinguished in the absence of cocaine. After extinction of self-administration behavior, the presentation of the aversive delay cue reinstated drug seeking. In vivo electrophysiology and voltammetry recordings in the nucleus accumbens measured the neural responses to both the delay and immediate drug cues after extinction. Interestingly, the presentation of the delay cue simultaneously decreased dopamine signaling and increased excitatory encoding of the immediate cue. Most importantly, the delay cue selectively enhanced the baseline activity of neurons that would later encode drug seeking. Together these observations reveal how cocaine cues can modulate not only affective state, but also the neurochemical and downstream neurophysiological environment of striatal circuits in a manner that promotes drug seeking

Opposite Thermodynamic Arrows of Time

A model in which two weakly coupled systems maintain opposite running thermodynamic arrows of time is exhibited. Each experiences its own retarded electromagnetic interaction and can be seen by the other. The possibility of opposite-arrow systems at stellar distances is explored and a relation to dark matter suggested.Comment: To appear in Phys. Rev. Let

Aversive Stimuli Drive Drug Seeking in a State of Low Dopamine Tone

Background Stressors negatively impact emotional state and drive drug seeking, in part, by modulating the activity of the mesolimbic dopamine system. Unfortunately, the rapid regulation of dopamine signaling by the aversive stimuli that cause drug seeking is not well characterized. In a series of experiments, we scrutinized the subsecond regulation of dopamine signaling by the aversive stimulus, quinine, and tested its ability to cause cocaine seeking. Additionally, we examined the midbrain regulation of both dopamine signaling and cocaine seeking by the stress-sensitive peptide, corticotropin releasing factor (CRF). Methods Combining fast-scan cyclic voltammetry with behavioral pharmacology, we examined the effect of intraoral quinine administration on nucleus accumbens dopamine signaling and hedonic expression in 21 male Sprague-Dawley rats. We tested the role of CRF in modulating aversion-induced changes in dopamine concentration and cocaine seeking by bilaterally infusing the CRF antagonist, CP-376395, into the ventral tegmental area (VTA). Results We found that quinine rapidly reduced dopamine signaling on two distinct time scales. We determined that CRF acted in the VTA to mediate this reduction on only one of these time scales. Further, we found that the reduction of dopamine tone and quinine-induced cocaine seeking were eliminated by blocking the actions of CRF in the VTA during the experience of the aversive stimulus. Conclusions These data demonstrate that stress-induced drug seeking can occur in a terminal environment of low dopamine tone that is dependent on a CRF-induced decrease in midbrain dopamine activity

Yang-Mills gravity in biconformal space

We write a gravity theory with Yang-Mills type action using the biconformal gauging of the conformal group. We show that the resulting biconformal Yang-Mills gravity theories describe 4-dim, scale-invariant general relativity in the case of slowly changing fields. In addition, we systematically extend arbitrary 4-dim Yang-Mills theories to biconformal space, providing a new arena for studying flat space Yang-Mills theories. By applying the biconformal extension to a 4-dim pure Yang-Mills theory with conformal symmetry, we establish a 1-1, onto mapping between a set of gravitational gauge theories and 4-dim, flat space gauge theories.Comment: 27 pages; paper emphasis shifted to focus on gravity; references adde

Bubbles created from vacuum fluctuation

We show that the bubbles $S^2\times S^2$can be created from vacuum fluctuation in certain De Sitter universe, so the space-time foam-like structure might really be constructed from bubbles of $S^2\times S^2$ in the very early inflating phase of our universe. But whether such foam-like structure persisted during the later evolution of the universe is a problem unsolved now.Comment: 6 page