BROKERS OF THE WORD: AN ESSAY IN THE SOCIAL HISTORY OF THE EARLY AMERICAN PRESS, 1639-1783

This dissertation explores the social context of printing and publishing from 1639 to 1783 through an analysis of the complete extant record of colonial printing and a collective biography of the printers, publishers and booksellers who comprised the press. Two general areas are explored. The first involves the size, stability, and growth of the press, the second, the structure of the trade at large. The early American press grew like the population it served and was characterized by a marked stability. The broad patterns of production and growth suggest that how much was printed depended largely upon the number of persons in the trade, which, in turn, depended upon successful demographic experiences. In all areas of colonial America, families formed the underlying structure of the trade, and their fortunes were those of the trade itself. The nature and extent of association among tradesmen is also explored. Here, the professional and familial networks of tradesmen are examined both as phenomena of personal association in colonial America and as the structure through which ideas, in the form of printed works, flowed from place to place. The extent of trade networks reached its zenith early in the eighteenth century, and thereafter declined as the size of the trade exceeded the ability of individuals to form associations with other tradesmen. The diminishing networks of tradesmen contributed to a marked provincialism of the early American press which was reflected in the declining inter-regional diffusion of printed works as the eighteenth century progressed

A near-infrared pyramid wavefront sensor for Keck adaptive optics: real-time controller

A new real-time control system will be implemented within the Keck II adaptive optics system to support the new near-infrared pyramid wavefront sensor. The new real-time computer has to interface with an existing, very productive adaptive optics system. We discuss our solution to install it in an operational environment without impacting science. This solution is based on an independent SCExAO-based pyramid wavefront sensor realtime processor solution using the hardware interfaces provided by the existing Keck II real-time controller. We introduce the new pyramid real-time controller system design, its expected performance, and the modification of the operational real-time controller to support the pyramid system including interfacing with the existing deformable and tip-tilt mirrors. We describe the integration of the Saphira detector-based camera and the Boston Micromachines kilo-DM in this new architecture. We explain the software architecture and philosophy, the shared memory concept and how the real-time computer uses the power of GPUs for adaptive optics control. We discuss the strengths and weaknesses of this architecture and how it can benefit other projects. The motion control of the devices deployed on the Keck II adaptive optics bench to support the alignment of the light on the sensors is also described. The interfaces, developed to deal with the rest of the Keck telescope systems in the observatory distributed system, are reviewed. Based on this experience, we present which design ideas could have helped us integrate the new system with the previous one and the resultant performance gains

A meta-analysis of third wave mindfulness-based cognitive behavioral therapies for older people

Objectives: The aim of this study is to review the effectiveness of third wave mindfulness-based cognitive behavioral therapies (CBTs) for depressive or anxiety symptomatology in older adults across a wide range of physical and psychological conditions. Methods: Electronic literature databases were searched for articles, and random-effects meta-analysis was conducted. Results: Ten studies met the inclusion criteria, of which nine reported the efficacy of interventions on depressive symptoms and seven on anxiety symptoms. Effect-size estimates suggested that mindfulness-based CBT is moderately effective on depressive symptoms in older adults (g = 0.55). The results demonstrated a similar level of overall effect size for anxiety symptoms (g = 0.58). However, there was a large heterogeneity, and publication bias was evident in studies reporting outcomes on anxiety symptoms, and thus, this observed efficacy for late-life anxiety may not be robust. The quality of the included studies varied. Only one study used an active psychological control condition. There were a limited number of studies that used an intent-to-treat (last observation carried forward method) analysis and reported appropriate methods for clinical trials (e.g., treatment-integrity reporting). Conclusions: Third wave mindfulness-based CBT may be robust in particular for depressive symptoms in older adults. We recommend that future studies (i) conduct randomized controlled trials with intent-to-treat to compare mindfulness-based CBT with other types of psychotherapy in older people and (ii) improve study quality by using appropriate methods for checking treatment adherence, randomization, and blinding of assessors. Copyright © 2016 John Wiley & Sons, Ltd

A near-infrared pyramid wavefront sensor for Keck adaptive optics: real-time controller

A new real-time control system will be implemented within the Keck II adaptive optics system to support the new near-infrared pyramid wavefront sensor. The new real-time computer has to interface with an existing, very productive adaptive optics system. We discuss our solution to install it in an operational environment without impacting science. This solution is based on an independent SCExAO-based pyramid wavefront sensor realtime processor solution using the hardware interfaces provided by the existing Keck II real-time controller. We introduce the new pyramid real-time controller system design, its expected performance, and the modification of the operational real-time controller to support the pyramid system including interfacing with the existing deformable and tip-tilt mirrors. We describe the integration of the Saphira detector-based camera and the Boston Micromachines kilo-DM in this new architecture. We explain the software architecture and philosophy, the shared memory concept and how the real-time computer uses the power of GPUs for adaptive optics control. We discuss the strengths and weaknesses of this architecture and how it can benefit other projects. The motion control of the devices deployed on the Keck II adaptive optics bench to support the alignment of the light on the sensors is also described. The interfaces, developed to deal with the rest of the Keck telescope systems in the observatory distributed system, are reviewed. Based on this experience, we present which design ideas could have helped us integrate the new system with the previous one and the resultant performance gains

Adaptive optics with an infrared pyramid wavefront sensor at Keck

The study of cold or obscured, red astrophysical sources can significantly benefit from adaptive optics (AO) systems employing infrared (IR) wavefront sensors. One particular area is the study of exoplanets around M-dwarf stars and planet formation within protoplanetary disks in star-forming regions. Such objects are faint at visible wavelengths but bright enough in the IR to be used as a natural guide star for the AO system. Doing the wavefront sensing at IR wavelengths enables high-resolution AO correction for such science cases, with the potential to reach the contrasts required for direct imaging of exoplanets. To this end, a new near-infrared pyramid wavefront sensor (PyWFS) has been added to the Keck II AO system, extending the performance of the facility AO system for the study of faint red objects. We present the Keck II PyWFS, which represents a number of firsts, including the first PyWFS installed on a segmented telescope and the first use of an IR PyWFS on a 10-m class telescope. We discuss the scientific and technological advantages offered by IR wavefront sensing and present the design and commissioning of the Keck PyWFS. In particular, we report on the performance of the Selex Avalanche Photodiode for HgCdTe InfraRed Array detector used for the PyWFS and highlight the novelty of this wavefront sensor in terms of the performance for faint red objects and the improvement in contrast. The system has been commissioned for science with the vortex coronagraph in the NIRC2 IR science instrument and is being commissioned alongside a new fiber injection unit for NIRSPEC. We present the first science verification of the system—to facilitate the study of exoplanets around M-type stars

Adaptive optics with an infrared pyramid wavefront sensor at Keck

The study of cold or obscured, red astrophysical sources can significantly benefit from adaptive optics (AO) systems employing infrared (IR) wavefront sensors. One particular area is the study of exoplanets around M-dwarf stars and planet formation within protoplanetary disks in star-forming regions. Such objects are faint at visible wavelengths but bright enough in the IR to be used as a natural guide star for the AO system. Doing the wavefront sensing at IR wavelengths enables high-resolution AO correction for such science cases, with the potential to reach the contrasts required for direct imaging of exoplanets. To this end, a new near-infrared pyramid wavefront sensor (PyWFS) has been added to the Keck II AO system, extending the performance of the facility AO system for the study of faint red objects. We present the Keck II PyWFS, which represents a number of firsts, including the first PyWFS installed on a segmented telescope and the first use of an IR PyWFS on a 10-m class telescope. We discuss the scientific and technological advantages offered by IR wavefront sensing and present the design and commissioning of the Keck PyWFS. In particular, we report on the performance of the Selex Avalanche Photodiode for HgCdTe InfraRed Array detector used for the PyWFS and highlight the novelty of this wavefront sensor in terms of the performance for faint red objects and the improvement in contrast. The system has been commissioned for science with the vortex coronagraph in the NIRC2 IR science instrument and is being commissioned alongside a new fiber injection unit for NIRSPEC. We present the first science verification of the system—to facilitate the study of exoplanets around M-type stars

Keck Planet Imager and Characterizer: demonstrating advanced exoplanet characterization techniques for future extremely large telescopes (Conference Presentation)

The Keck Planet Imager and Characterizer (KPIC) is an upgrade to the Keck II adaptive optics system enabling high contrast imaging and high-resolution spectroscopic characterization of giant exoplanets in the mid-infrared (2-5 microns). The KPIC instrument will be developed in phases. Phase I entails the installation of an infrared pyramid wavefront sensor (PyWFS) based on a fast, low-noise SAPHIRA IR-APD array. The ultra-sensitive infrared PyWFS will enable high contrast studies of infant exoplanets around cool, red, and/or obscured targets in star forming regions. In addition, the light downstream of the PyWFS will be coupled into an array of single-mode fibers with the aid of an active fiber injection unit (FIU). In turn, these fibers route light to Keck's high-resolution infrared spectrograph NIRSPEC, so that high dispersion coronagraphy (HDC) can be implemented for the first time. HDC optimally pairs high contrast imaging and high-resolution spectroscopy allowing detailed characterization of exoplanet atmospheres, including molecular composition, spin measurements, and Doppler imaging. We will provide an overview of the instrument, its science scope, and report on recent results from on-sky commissioning of Phase I. We will discuss plans for optimizing the instrument to seed designs for similar modes on extremely large telescopes

Engolo and Capoeira. From Ethnic to Diasporic Combat Games in the Southern Atlantic

This article provides a re-examination of the main Afrocentric narrative of capoeira origins, the engolo or ‘Zebra Dance’, in light of historical primary sources and new ethnographic evidence gathered during fieldwork in south-west Angola. By examining engolo’s bodily techniques, its socio-historical context and cultural meanings, the piece emphasises its insertion into a pastoral lifestyle and highlights the relatively narrow ethnic character of the practice in Angola. This analysis and the comparison with capoeira helps us to develop certain hypotheses about the formation, migration, and re-invention of diasporic combat games between southern Angola and coastal Brazil, and more broadly, to increase our understanding of how African cultures spread across the southern Atlantic

The Princeton Protein Orthology Database (P-POD): A Comparative Genomics Analysis Tool for Biologists

Many biological databases that provide comparative genomics information and tools are now available on the internet. While certainly quite useful, to our knowledge none of the existing databases combine results from multiple comparative genomics methods with manually curated information from the literature. Here we describe the Princeton Protein Orthology Database (P-POD, http://ortholog.princeton.edu), a user-friendly database system that allows users to find and visualize the phylogenetic relationships among predicted orthologs (based on the OrthoMCL method) to a query gene from any of eight eukaryotic organisms, and to see the orthologs in a wider evolutionary context (based on the Jaccard clustering method). In addition to the phylogenetic information, the database contains experimental results manually collected from the literature that can be compared to the computational analyses, as well as links to relevant human disease and gene information via the OMIM, model organism, and sequence databases. Our aim is for the P-POD resource to be extremely useful to typical experimental biologists wanting to learn more about the evolutionary context of their favorite genes. P-POD is based on the commonly used Generic Model Organism Database (GMOD) schema and can be downloaded in its entirety for installation on one's own system. Thus, bioinformaticians and software developers may also find P-POD useful because they can use the P-POD database infrastructure when developing their own comparative genomics resources and database tools