145 research outputs found
The Effects of War as a Basis to Consider Six Novels by Ernest Hemingway and F. Scott Fitzgerald
Curiously, the issue of war has never been considered a solid basis for examining the works of Ernest Hemingway and F. Scott Fitzgerald. Yet one common thread running through the body of their work is war. A study of the authorsā attitudes toward war and their charactersā responses to war in Hemingwayās A Farewell to Arms (1929), For Whom the Bell Tolls (1940), The Sun Also Rises (1926), and Fitzgeraldās This Side of Paradise (1920), The Great Gatsby (1925), and Tender Is the Night (1934), yields several conclusions. Hemingwayās and Fitzgeraldās works reveal two different types of human responses to the effects of war while the characters search for ways to attain quality in life. Both the Hemingway and Fitzgerald protagonists suffer from the chaotic environment wrought by war. However, contemporary readers should find Fitzgeraldās characters particularly relevant because they confront a dilemma that mirrors more realistically manās struggle for salvation in modern, post-war society.
The element of war shapes the lives of both sets of characters, and yet very little criticism exists which presents war as a basis to consider any of the works by Hemingway and Fitzgerald together. The critics traditionally see war as having a major impact on the life and works of Ernest Hemingway; in contrast, most critics see war as playing no significant role in the life and works of Fitzgerald. However, both writersā lives were shaped immensely by war. Biographically, Hemingway volunteered to serve in Italy during World War I and was a volunteer journalist in Spain during the Spanish Civil war, experiences that helped to shape his strong sense of masculinity and superiority; though Fitzgerald never served in a war, the fact helped to create his deep sense of inferiority and failure as a man. Both menās experiences with war helped to formulate attitudes reflected in the fiction and account, in part, for the substantial differences in their approaches to theme and setting. So, the effects of war provide a valid basis for considering the lives, and subsequently, the works of Hemingway and Fitzgerald
Use of a novel Fƶrster resonance energy transfer method to identify locations of site-bound metal ions in the U2āU6 snRNA complex
U2 and U6 snRNAs pair to form a phylogenetically conserved complex at the catalytic core of the spliceosome. Interactions with divalent metal ions, particularly Mg(II), at specific sites are essential for its folding and catalytic activity. We used a novel Fƶrster resonance energy transfer (FRET) method between site-bound luminescent lanthanide ions and a covalently attached fluorescent dye, combined with supporting stoichiometric and mutational studies, to determine locations of site-bound Tb(III) within the human U2āU6 complex. At pH 7.2, we detected three metal-ion-binding sites in: (1) the consensus ACACAGA sequence, which forms the internal loop between helices I and III; (2) the four-way junction, which contains the conserved AGC triad; and (3) the internal loop of the U6 intra-molecular stem loop (ISL). Binding at each of these sites is supported by previous phosphorothioate substitution studies and, in the case of the ISL site, by NMR. Binding of Tb(III) at the four-way junction and the ISL sites was found to be pH-dependent, with no ion binding observed below pH 6 and 7, respectively. This pH dependence of metal ion binding suggests that the local environment may play a role in the binding of metal ions, which may impact on splicing activity
Generic 3D Representation via Pose Estimation and Matching
Though a large body of computer vision research has investigated developing
generic semantic representations, efforts towards developing a similar
representation for 3D has been limited. In this paper, we learn a generic 3D
representation through solving a set of foundational proxy 3D tasks:
object-centric camera pose estimation and wide baseline feature matching. Our
method is based upon the premise that by providing supervision over a set of
carefully selected foundational tasks, generalization to novel tasks and
abstraction capabilities can be achieved. We empirically show that the internal
representation of a multi-task ConvNet trained to solve the above core problems
generalizes to novel 3D tasks (e.g., scene layout estimation, object pose
estimation, surface normal estimation) without the need for fine-tuning and
shows traits of abstraction abilities (e.g., cross-modality pose estimation).
In the context of the core supervised tasks, we demonstrate our representation
achieves state-of-the-art wide baseline feature matching results without
requiring apriori rectification (unlike SIFT and the majority of learned
features). We also show 6DOF camera pose estimation given a pair local image
patches. The accuracy of both supervised tasks come comparable to humans.
Finally, we contribute a large-scale dataset composed of object-centric street
view scenes along with point correspondences and camera pose information, and
conclude with a discussion on the learned representation and open research
questions.Comment: Published in ECCV16. See the project website
http://3drepresentation.stanford.edu/ and dataset website
https://github.com/amir32002/3D_Street_Vie
Effect on birth outcomes of a formalised approach to care in hospital labour assessment units: international, randomised controlled trial
Objective To determine if a complex nursing and midwifery intervention in hospital labour assessment units would increase the likelihood of spontaneous vaginal birth and improve other maternal and neonatal outcomes
The Effectiveness of a Route Crossing Tool in a Simulated New York Airspace
Congested airspace is the cause of many delays in the terminal area and these delays can have a ripple effect on the rest of a nation's airspace. The New York terminal area is an example of where this happens in the U. S. An important goal, therefore, is to increase the efficiency of operations in congested terminal airspace where possible. Modeling studies of arrival and departure flows have shown that sharing of arrival and departure airspace increases efficiency in terminal operations. One source of inefficiency in terminal operations is that departure aircraft are frequently held level under arrival flows when it would be more efficient to climb the departure aircraft earlier. A Route Crossing Tool was developed to help controllers climb Newark (EWR) departures to the south earlier by temporarily sharing airspace with arrivals coming into LaGuardia (LGA) from the south. Instead of flying under the arrivals, a departure to the south could climb earlier by flying through the arrival airspace if there was a suitable gap between arrivals. A Human-in-the-Loop (HITL) simulation was conducted in this environment which compared three tool conditions: Baseline (no tool), a Single Route Crossing tool in which one route through the arrival flow was evaluated for crossing, and a Multi-Route Crossing tool in which five parallel routes were evaluated. In all conditions, the departures could be held level under the arrival flow. The results showed that controllers climbed a higher proportion of departures in the Multi-Route tool condition than in the other two conditions, with a higher proportion of departures climbed in smaller gaps and in front of trailing arrivals. The controllers indicated that the Multi-Route and Single Route tools helped them estimate distances more accurately and rated safety, workload, and coordination in the simulation as acceptable
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Treating sample covariances for use in strongly coupled atmosphere-ocean data assimilation
Strongly coupled data assimilation requires cross-domain forecast error covariances; information from ensembles can be used, but limited sampling means that ensemble derived error covariances are routinely rank deficient and/or ill-conditioned and marred by noise. Thus they require modification before they can be incorporated into a standard assimilation framework. Here, we compare methods for improving the rank and conditioning of multivariate sample error covariance matrices for coupled atmosphere-ocean data assimilation. The first method, reconditioning, alters the matrix eigenvalues directly; this preserves the correlation structures but does not remove sampling noise. We show it is better to recondition the correlation matrix rather than the covariance matrix as this prevents small but dynamically important modes from being lost. The second method, model state-space localisation via the Schur product, effectively removes sample noise but can dampen small cross-correlation signals. A combination that exploits the merits of each is found to offer an effective alternative
Development of a Route Crossing Tool for Shared Airspace Environments
In current-day Terminal Radar Approach Control (TRACON) operations, departure and arrival controllers maintain separate and dedicated airspace for their respective traffic flows. Although this practice has obvious safety features, it also leads to inefficiencies; for example, departure aircraft may be routinely capped beneath arrival airspace. With the right decision-support and coordination tools, departures could continue to climb through arrival airspace when sufficient gaps exist. Previous studies of shared airspace have examined pre-arranged coordination procedures, as well as tools that gave feedback to the controllers on where gaps between arrivals were located and whether the departure aircraft could be scheduled to fly through those gaps [1, 2, 3, 4]. Since then, the Route Crossing Tool (RCT) has been developed to allow controllers to assess multiple pre-defined route options at points where the arrivals and departures cross, thereby increasing the possibility of climbing a departure through an arrival gap.The RCT aids in ensuring lateral separation between departure and arrival aircraft that pass through the same altitude. Since the RCT can be applied tactically, it can enable aircraft to fly through arrival flows even if these aircraft depart outside scheduled times. The RCT makes use of a set of predefined parallel departure routes crossing the arrival flow at equidistant intersecting points on the arrival route. The RCT uses the Estimated Time of Arrival (ETA) of the departure aircraft at each intersecting point to calculate the lateral separation with the neighboring arrivals when it crosses that point; this information is graphically displayed to the controller. Additionally, the RCT incorporates forecast winds in its ETA predictions.Multiple prototypes of the RCT have been iteratively developed with feedback from Subject Matter Experts (SMEs). This paper presents the final design, the design process, and lessons learned. Initial results from a simulation suggest that the tool was successful in helping controllers to safely climb more aircraft. Controller feedback on the tool was also positive
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