271 research outputs found
Revealing spatio-spectral electroencephalographic dynamics of musical mode and tempo perception by independent component analysis.
BackgroundMusic conveys emotion by manipulating musical structures, particularly musical mode- and tempo-impact. The neural correlates of musical mode and tempo perception revealed by electroencephalography (EEG) have not been adequately addressed in the literature.MethodThis study used independent component analysis (ICA) to systematically assess spatio-spectral EEG dynamics associated with the changes of musical mode and tempo.ResultsEmpirical results showed that music with major mode augmented delta-band activity over the right sensorimotor cortex, suppressed theta activity over the superior parietal cortex, and moderately suppressed beta activity over the medial frontal cortex, compared to minor-mode music, whereas fast-tempo music engaged significant alpha suppression over the right sensorimotor cortex.ConclusionThe resultant EEG brain sources were comparable with previous studies obtained by other neuroimaging modalities, such as functional magnetic resonance imaging (fMRI) and positron emission tomography (PET). In conjunction with advanced dry and mobile EEG technology, the EEG results might facilitate the translation from laboratory-oriented research to real-life applications for music therapy, training and entertainment in naturalistic environments
Relationship between the morphology of A-1 segment of anterior cerebral artery and anterior communicating artery aneurysms
Background: The anterior communicating artery (ACoA) is one of the most frequent sites for cerebral aneurysm. The peculiar directions of projection of aneurysms offer great challenges to clinical treatment. Objetives: To establish the relationship between morphology of A-1 segment of anterior cerebral artery (ACA) and aneurismal projection. Methods: Randomly selected digital subtraction angiography data of 264 anterior communicating artery aneurysms (ACoAA) cases and 296 cases of other cerebral vascular diseases in the same period were retrospectively analyzed. Results: Among 264 ACoAA patients, the morphology of A-1 segment showed type â… a in 158 sides, type â… b in 11, type â…ˇa in 35, type â…ˇb in 87, type â…˘ in 171 and absence in 66. The morphology of A-1 segment in 296 patients with other cerebral vascular diseases displayed type â… a in 195 sides, type â… b in 20, type â…ˇa in 47, type â…ˇ b in 74, type â…˘ in 217 and absence in 39. The non-visualization of A-1 segment in the group of ACoAA occurred more than in the control group (χ2=11.482, p=0.001). The classifications of ACoAAs in 264 patients were confirmed as anterior-superior type in 121 cases, anterior-inferior type in 105, complicated type in 16, posterior-inferior type in 12 and posterior-superior type in 10. The correlation between morphology of A-1 segment of ACA and classifications of ACoAA was significant (p=0.000; C=0.619, p=0.000). The direction of ACoAA was downward when the A-1 segment of ACA was Type â… a or Type â…ˇa, and was upward when it was Type â… b or Type â…ˇb,and was upward or downward or complicated when it was Type â…˘. Conclusion: The relationship between morphology of A-1 segment of ACA and classification of ACoAA is clarified in the present study, which is helpful to surgical treatment.Keywords: anterior cerebral artery; morphology of A-1 segment; projection of anterior communicating artery aneurysmAfrican Health sciences Vol 14 No. 1 March 201
Apoptosis of supraoptic AVP neurons is involved in the development of central diabetes insipidus after hypophysectomy in rats
<p>Abstract</p> <p>Background</p> <p>It has been reported that various types of axonal injury of hypothalamo-neurohypophyseal tract can result in degeneration of the magnocellular neurons (MCNs) in hypothalamus and development of central diabetes insipidus (CDI). However, the mechanism of the degeneration and death of MCNs after hypophysectomy in vivo is still unclear. This present study was aimed to disclose it and to figure out the dynamic change of central diabetes insipidus after hypophysectomy.</p> <p>Results</p> <p>The analysis on the dynamic change of daily water consumption (DWC), daily urine volume(DUV), specific gravity of urine(USG) and plasma vasopressin concentration showed that the change pattern of them was triphasic and neuron counting showed that the degeneration of vasopressin neurons began at 10 d, aggravated at 20 d and then stabilized at 30 d after hypophysectomy. There was marked upregulation of cleaved Caspase-3 expression of vasopressin neurons in hypophysectomy rats. A "ladder" pattern of migration of DNA internucleosomal fragments was detected and apoptotic ultrastructure was found in these neurons. There was time correlation among the occurrence of diabetes insipidus, the changes of plasma vasopressin concentration and the degeneration of vasopressin neurons after hypophysectomy.</p> <p>Conclusion</p> <p>This study firstly demonstrated that apoptosis was involved in degeneration of supraoptic vasopressin neurons after hypophysectomy in vivo and development of CDI. Our study on time course and correlations among water metabolism, degeneration and apoptosis of vasopressin neurons suggested that there should be an efficient therapeutic window in which irreversible CDI might be prevented by anti-apoptosis.</p
Comprehensive analysis on the magnetic field error of a K–Rb–21Ne comagnetometer with low-frequency bias magnetic field sensitivity
The spin-exchange relaxation-free comagnetometer (SERFC) is of important research value compared to existing high-precision gyroscopes because of its extremely high theoretical limit sensitivity and long-term stability, in which one significant limiting factor is the magnetic field error. First, the relationship between the magnetic field gradient and the nuclear spin relaxation mechanism is introduced into the frequency response and steady-state response models of SERFC. Then, a novel method for suppression of the low-frequency magnetic field error based on the modified bias magnetic field sensitivity model is proposed. Finally, the effectiveness of the proposed suppression methods is demonstrated by optimizing the cell temperature, pump light power, and compensation magnetic field gradient to increase the suppression factor by 72.19%, 20.24%, and 69.86%, and the corresponding bias instability increased by 55.41%, 20.84%, and 27.63%, respectively. This study contributes to improving the long-term zero bias stability of the SERFC
Intensity of Caring About an Action’s Side-Effect Mediates Attributions of Actor’s Intentions
The side-effect effect (SEE) is the observation that people’s intuition about whether an action was intentional depends on whether the outcome is good or bad. The asymmetric response, however, does not represent all subjects’ judgments (Nichols and Ulatowski, 2007). It remains unexplored on subjective factors that can mediate the size of SEE. Thus, the current study investigated whether an individual related factor, specifically, whether adults’ intensity of caring about an outcome of someone’s actions influences their judgments about whether that person intended the outcome. We hypothesized that participants’ judgments about fictional agents’ responsibility for their action’s side-effects would depend on how much they care about the domain of the side-effect. In two experiments, the intensity of caring affected participants’ ascription of intention to an agent’s negative unintended side-effect. The stronger ascription of intentionality to negative than positive side-effects (i.e., the SEE; Knobe, 2003) was found only in domains in which participants reported higher levels of caring. Also, the intensity of caring increased intentionality attributions reliably for negative side-effects but not for positive side-effects. These results suggest that caring about a domain mediates an asymmetrical ascription of intentionality to negative more than positive side-effects
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