1,292 research outputs found

    Facebook and Google Usage in Taiwan’s College Students

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    This study proposes and tests a research model which was developed based on the uses-and-gratifications theory. The aim of this study was to investigate if selected factors have differential predicting power on the use of Facebook and Google service in Taiwan. This study employed seven constructs: purposive value, hedonic value, social identity, social support, interpersonal relationship, personality traits, and intimacy as the factors predicting Facebook and Google usage. An electronic survey technique was used to collect data from Internet. The results showed that hedonic value and social identity constructs can significantly predict Facebook usage and purposive value has significant predicting power on Google usage. The construct intimacy is the most significant factor for both Google and Facebook usages. Our findings make suggestions for social network sites (SNSs) providers that to differentiate their SNSs quality from others’, both functional aspects and emotional factors need to be taken into consideration

    Nonsteroidal Anti-Inflammatory Drugs for Wounds: Pain Relief or Excessive Scar Formation?

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    The inflammatory process has direct effects on normal and abnormal wound healing. Hypertrophic scar formation is an aberrant form of wound healing and is an indication of an exaggerated function of fibroblasts and excess accumulation of extracellular matrix during wound healing. Two cytokines—transforming growth factor-β (TGF-β) and prostaglandin E2 (PGE2)—are lipid mediators of inflammation involving wound healing. Overproduction of TGF-β and suppression of PGE2 are found in excessive wound scarring compared with normal wound healing. Nonsteroidal anti-inflammatory drugs (NSAIDs) or their selective cyclooxygenase-2 (COX-2) inhibitors are frequently used as a pain-killer. However, both NSAIDs and COX-2 inhibitors inhibit PGE2 production, which might exacerbate excessive scar formation, especially when used during the later proliferative phase. Therefore, a balance between cytokines and medication in the pathogenesis of wound healing is needed. This report is a literature review pertaining to wound healing and is focused on TGF-β and PGE2

    Integrating Dictionary and Web N-grams for Chinese Spell Checking

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    Abstract Chinese spell checking is an important component of many NLP applications, including word processors, search engines, and automatic essay rating. Nevertheless, compared to spell checkers for alphabetical languages (e.g., English or French), Chinese spell checkers are more difficult to develop because there are no word boundaries in the Chinese writing system and errors may be caused by various Chinese input methods. In this paper, we propose a novel method for detecting and correcting Chinese typographical errors. Our approach involves word segmentation, detection rules, and phrase-based machine translation. The error detection module detects errors by segmenting words and checking word and phrase frequency based on compiled and Web corpora. The phonological or morphological typographical errors found then are corrected by running a decoder based on the statistical machine translation model (SMT). The results show that the proposed system achieves significantly better accuracy in error detection and more satisfactory performance in error correction than the state-of-the-art systems

    Associations between blood glucose level and outcomes of adult in-hospital cardiac arrest: a retrospective cohort study

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    Additional file 3: Table S3. Features, interventions, and outcomes of cardiac arrest events stratified by the presence of measurement of blood glucose level after sustained return of spontaneous circulation

    Peripheral primitive neuroectodermal tumor of the ovary with torsion

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    AbstractPeripheral primitive neuroectodermal tumors (pPNETs) of the ovary are rare monophasic teratomas, and fewer than 100 cases have been reported in the literature. pPNETs mainly involve young women during their reproductive age, therefore, accurate diagnosis followed by multimodal treatment should be taken into consideration for fertility preservation. We report a patient with stage IA pPNET of the ovary presenting with acute abdominal pain secondary to torsion that was successfully managed by fertility-sparing surgery and six courses of combination chemotherapy with vincristine, Adriamycin, and cyclophosphamide. She has had a disease-free survival of >3 years. This brief review demonstrates the clinical course of pPNET and summarizes the literature to show that clinical stage at the time of diagnosis is the most important prognostic factor and that the vast majority of recurrences are observed within 10 years

    Reliability of flexible low temperature poly-silicon thin film transistor

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    This work reports the effect of mechanical stress-induced degradation in flexible low-temperature polycrystalline-silicon thin-film transistors. After 100,000 iterations of channel-width-direction mechanical compression at R=2mm, a significant shift of extracted threshold voltage and an abnormal hump at the subthreshold region were found. Simulation reveals that both the strongest mechanical stress and electrical field takes place at both sides of the channel edge, between the polycrystalline silicon and gate insulator. The gate insulator suffered from a serious mechanical stress and result in a defect generation in the gate insulator. The degradation of the threshold voltage shift and the abnormal hump can be ascribed to the electron trapping in these defects. In addition, this work introduced three methods to reduce the degradation cause by the mechanical stress, including the quality improvement of the gate insulator, organic trench structure and active layer with a wing structure. Please click Additional Files below to see the full abstract

    Intramuscular electroporation with the pro-opiomelanocortin gene in rat adjuvant arthritis

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    Endogenous opioid peptides have an essential role in the intrinsic modulation and control of inflammatory pain, which could be therapeutically useful. In this study, we established a muscular electroporation method for the gene transfer of pro-opiomelanocortin (POMC) in vivo and investigated its effect on inflammatory pain in a rat model of rheumatoid arthritis. The gene encoding human POMC was inserted into a modified pCMV plasmid, and 0–200 μg of the plasmid-POMC DNA construct was transferred into the tibialis anterior muscle of rats treated with complete Freund's adjuvant (CFA) with or without POMC gene transfer by the electroporation method. The safety and efficiency of the gene transfer was assessed with the following parameters: thermal hyperalgesia, serum adrenocorticotropic hormone (ACTH) and endorphin levels, paw swelling and muscle endorphin levels at 1, 2 and 3 weeks after electroporation. Serum ACTH and endorphin levels of the group into which the gene encoding POMC had been transferred were increased to about 13–14-fold those of the normal control. These levels peaked 1 week after electroporation and significantly decreased 2 weeks after electroporation. Rats that had received the gene encoding POMC had less thermal hypersensitivity and paw swelling than the non-gene-transferred group at days 3, 5 and 7 after injection with CFA. Our promising results showed that transfer of the gene encoding POMC by electroporation is a new and effective method for its expression in vivo, and the analgesic effects of POMC cDNA with electroporation in a rat model of rheumatoid arthritis are reversed by naloxone
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