464 research outputs found

    Study on the Safety Management of Connected and Autonomous Vehicle Test Roads Based on the Evaluation of Traffic Safety Facilities

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    More and more connected and autonomous vehicle (CAV) open test roads reconstructed on the basis of traditional roads have appeared in China. However, the management policies vary, which makes the traffic environment complicated. This paper takes CAV test road safety management as the research aim and investigates the open test condition through the evaluation of the traffic safety facilities. Indicators were rigorously screened, then the game theory model was used to determine the combination weight of the indicators, and the set pair analysis was applied to solve the uncertain problems. A case study for the CAV test road network of a city in central China was implemented and the results show, regarding the traffic safety facilities’ condition, among the 20 sections of the city’s CAV test road network, 15% of which are at an excellent level, 75% of which are at a good level and 10% of which are at a moderate level; road signs, guardrail facilities, isolation facilities and road features are the main limiting factors affecting the level of traffic safety facilities. Based on the results, recommendations have been made for the transport management authorities in the aspects of safety management policy-making and facilities maintenance

    Cryo-EM Structure of a Novel Calicivirus, Tulane Virus.

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    Tulane virus (TV) is a newly isolated cultivatable calicivirus that infects juvenile rhesus macaques. Here we report a 6.3 Ă… resolution cryo-electron microscopy structure of the TV virion. The TV virion is about 400 Ă… in diameter and consists of a T = 3 icosahedral protein capsid enclosing the RNA genome. 180 copies of the major capsid protein VP1 (~57 KDa) are organized into two types of dimers A/B and C/C and form a thin, smooth shell studded with 90 dimeric protrusions. The overall capsid organization and the capsid protein fold of TV closely resemble that of other caliciviruses, especially of human Norwalk virus, the prototype human norovirus. These close structural similarities support TV as an attractive surrogate for the non-cultivatable human noroviruses. The most distinctive feature of TV is that its C/C dimers are in a highly flexible conformation with significantly reduced interactions between the shell (S) domain and the protruding (P) domain of VP1. A comparative structural analysis indicated that the P domains of TV C/C dimers were much more flexible than those of other caliciviruses. These observations, combined with previous studies on other caliciviruses, led us to hypothesize that the enhanced flexibility of C/C dimer P domains are likely required for efficient calicivirus-host cell interactions and the consequent uncoating and genome release. Residues in the S-P1 hinge between the S and P domain may play a critical role in the flexibility of P domains of C/C dimers

    An emergency dispatch model considering the urgency of the requirement for reliefs in different disaster areas

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    Purpose: Frequent sudden-onset disasters which have threatened the survival of human and the development of society force the public to pay an increasing attention to emergency management. A challenging task in the process of emergency management is emergency dispatch of reliefs. An emergency dispatch model considering the urgency of the requirement for reliefs in different disaster areas is proposed in this paper to dispatch reliefs reasonably and reduce the effect of sudden-onset disasters. Design/methodology/approach: Firstly, quantitative assessment on the urgency of the requirement for reliefs in different disaster areas is done by an evaluation method based on Fuzzy Comprehensive Evaluation and improved Evidence Reasoning which is proposed in this paper. And then based the quantitative results, an emergency dispatch model aiming to minimize the response time, the distribution cost and the unsatisfied rate of the requirement for reliefs is proposed, which reflects the requests of disaster areas under emergency, including the urgency of requirement, the economy of distribution and the equity of allocation. Finally, the Genetic Algorithm is improved based on the adaptive crossover and mutation probability function to solve the emergency dispatch model. Findings: A case that the Y hydraulic power enterprise carries on emergency dispatch of reliefs under continuous sudden-onset heavy rain is given to illustrate the availability of the emergency dispatch model proposed in this paper. The results show that the emergency dispatch model meets the distribution priority requirement of disaster area with the higher urgency, so that reliefs are supplied more timely. Research limitations/implications: The emergency dispatch model faced to large scale sudden-onset disasters is complex. The quantity of reliefs that disaster area requires and the running time of vehicles are viewed as available information, and the problem that how to obtain the information is not considered. Practical implications: The emergency dispatch model considering the urgency of the requirement for reliefs in different disaster areas is applicable to a realistic emergency dispatch of reliefs under sudden-onset disasters and the research results is the foundation of further research on the problem of emergency management. Originality/value: This paper proposes emergency dispatch model considering the urgency of the requirement for reliefs in different disaster areas which can meet the realistic requirement that the disaster area with the higher urgency has an priority to obtain the reliefs and make reliefs be distributed timely.Peer Reviewe

    Fungal Diversity of Traditional Oats Tianpei and the Fermentation Effects of Rhizopus Oryzae on Tianpei Properties

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    The fungal diversity of five sweet fermented oats samples in China was studied by Illumina sequencing. The results showed that the abundance of Mucoromycota and Ascomycota peaked in the oats Tianpei samples, and a bit Basidiomycota were also included. As to genus, Rhizopus had the highest abundance, followed by unclassified_p_Ascomycota, Saccharomyces and Issatchenkia. Principal component analysis (PCA) indicated that five kinds of oats Tianpei samples formed their own fungal clusters. The biomarker taxa of oats Tianpei were identified by Lefse, including Mucor and Pichia. The fungal composition of oats Tianpei was significantlly related to the chemical composition of oats Tianpei (lactic acid, free fatty acid, amino acid, reducing sugar, etc). The fermentation effects of Rhizopus oryzae on the chemical composition of oats Tianpei were studied also. The fermentation of Rhizopus oryzae significantly increased the chemical composition in oats Tianpei. The research provided a theoretical basis for the study of microbial flora, the discovery of related microbial resources, the fermented modification grains, and the improvement of oats Tianpei quality

    Relationship between teaching quality factors and employability among Technology Management students

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    Education system within higher education institution (HEI) is constantly evolved to enhance students’ employability in respond to the change of social-economy and technological revolution. Empirical research revealed that teaching quality is extremely important for the development of students’ employability attributes. Hence, one of the biggest challenges for HEI is to continuously improve teaching quality with the aim to enhance student employability. This study examined the influence of teaching quality on the employability of Technology Management students. Three important factors for teaching quality are identified from literature review comprising of learner quality, learning environment quality and content quality. This study used quantitative method to collect data via online questionnaire with 60 Technology Management students from a Business School within Malaysia responded. Data collected was analyzed using SPSS in term of normality, reliability, descriptive and Pearson correlation test. Finding from this study reveals that learning environment quality, content quality and learner quality are important, significant and positively correlated with employability. The main implication of this study is students’ employability could be assessed based on teaching quality directly instead of via students’ academic performance or employability attribute

    Comparative analyses of eight complete plastid genomes of two hemiparasitic Cassytha vines in the family Lauraceae

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    Cassytha is the sole genus of hemiparasitic vines (ca. 20 spp.) belonging to the Cassytheae tribe of the Lauraceae family. It is extensively distributed in tropical and subtropical regions. In this study, we determined the complete plastid genome sequences of C. filiformis and C. larsenii, which do not possess the typical quadripartite structure. The length of C. filiformis plastomes ranged from 114,215 to 114,618 bp, whereas that of C. larsenii plastomes ranged from 114,900 to 114,988 bp. Comparative genomic analysis revealed 1,013 mutation sites, four large intragenomic deletions, and five highly variable regions in the eight plastome sequences. Phylogenetic analyses based on 61 complete plastomes of Laurales species, 19 ITS sequences, and trnK barcodes from 91 individuals of Cassytha spp. confirmed a non-basal group comprising individuals of C. filiformis, C. larsenii, and C. pubescens in the family Lauraceae and proposed a sister relationship between C. filiformis and C. larsenii. Further morphological comparisons indicated that the presence or absence of hairs on the haustoria and the shape or size of fruits were useful traits for differentiating C. filiformis and C. larsenii

    The role and safety of UVA and UVB in UV-induced skin erythema

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    BackgroundDifferent wavelengths of ultraviolet (UV) light cause skin damage through different mechanisms. Minimal erythema dose (MED) is usually used to clinically evaluate skin sensitivity to ultraviolet radiation by inducing skin erythema using ultraviolet B (UVB) or ultraviolet A (UVA) + UVB.AimsIn this study, we detected changes in the blood flow at the MED erythema caused by UVB and UVA + UVB radiation through optical coherence tomography (OCT) to explain the role of different bands of ultraviolet rays in erythema induction.MethodsTwo MED irradiation areas on the subjects' back were irradiated with UVB alone or UVA + UVB (UVA: UVB = 8:1). The absolute energy of UVB remained the same in UVB and UVA+UVB. At 24 h after the irradiation, the changes in the blood flow in the MED area were detected using OCT.ResultsCompared with the blank control, the maximum blood flow depth, blood flow peak, and total blood flow of UVB-MED and UVA+UVB-MED were significantly increased. Notably, the maximum blood flow depth and blood flow peak of UVB-MED were higher than UVA+UVB-MED. There was no significant difference in total blood perfusion between UVA+UVB-MED and UVB-MED. Under the same UVB energy, the skin erythema caused by UVA + UVB was weaker than UVB alone.ConclusionsThe analysis of local blood flow by OCT showed that the peak and maximum depth of local blood flow caused by UVB alone were significantly higher than UVA + UVB

    Soft modes in hot QCD matter

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    The chiral crossover of QCD at finite temperature and vanishing baryon density turns into a second order phase transition if lighter than physical quark masses are considered. If this transition occurs sufficiently close to the physical point, its universal critical behaviour would largely control the physics of the QCD phase transition. We quantify the size of this region in QCD using functional approaches, both Dyson-Schwinger equations and the functional renormalisation group. The latter allows us to study both critical and non-critical effects on an equal footing, facilitating a precise determination of the scaling regime. We find that the physical point is far away from the critical region. Importantly, we show that the physics of the chiral crossover is dominated by soft modes even far beyond the critical region. While scaling functions determine all thermodynamic properties of the system in the critical region, the order parameter potential is the relevant quantity away from it. We compute this potential in QCD using the functional renormalisation group and Dyson-Schwinger equations and provide a simple parametrisation for phenomenological applications.Comment: 7+8 pages, 5+4 figure
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