488 research outputs found
Formation of a new rural power structure and the failure of gender in utopia: : lesbian image and its metaphors in Wildcat Lake
Chen Yingsong created Wildcat Lake not just for telling a story about lesbians. By describing how Xiangâer, a rural woman, becomes a lesbian in the villages, we can see the ârichnessâ and âmetaphorical meaningâ of the lesbian symbol. As far as Wildcat Lake is concerned, it is more worthy of discussing how Xiangâer becomes a lesbian, which is not only about sex or gender, but also about political and economic oppression; therefore, the so-called gender in Utopia will inevitably fail. Furthermore, the loss of rural subjectivity during modernization and transformation, the subsequent new power structure, and the resulting oppression and exploitation are the fundamental reasons for Xiangâer to become a lesbian and eventually âkill her husbandâ.
Chen Yingsong created Wildcat Lake not just for telling a story about lesbians but also bydescribing how Xiangâer, a rural woman, becomes a lesbian in the villages. We can see the ârichnessâand âmetaphorical meaningâ of the lesbian symbol. As far as Wildcat Lake is concerned, it is moreworthy of discussing how Xiangâer becomes a lesbian, which is not only about sex or gender, but alsoabout political and economic oppression. Therefore, the so-called gender in Utopia will inevitably fail.Furthermore, the loss of rural subjectivity during modernization and transformation, the subsequentnew power structure, and the resulting oppression and exploitation are the fundamental reasons forXiangâer to become a lesbian and eventually âkill her husbandâ
An intact laminated layer is important for the establishment of secondary Echinococcus multilocularis infection.
Echinococcus multilocularis causes alveolar echinococcosis primarily in rodents, but also in humans where it represents one of the most lethal helmintic infections. We used a susceptible mouse (C57BL/6) model to demonstrate failure in controlling secondary infection with the E. multilocularis metacestode, even when performed at the lowest possible infection dose. This was achieved by intraperitoneal or intrahepatic inoculation of a single parasite vesicle. In secondary infections, the primary physical barrier between the parasite and the host is constituted by the acellular laminated layer (LL), which is predominantly composed of high-molecular-weight glycans and surrounds the entire metacestode. Only those metacestode structures which exhibited an intact LL were successful in establishing infection, whereas metacestodes which were punctured - thus exhibiting an opened LL and thereby an accessible germinal layer - were no longer infective. Conversely, both types of vesicle survived in vivo maintenance, as assessed by RT-PCR based upon II/3 gene expression. In consequence, the encapsulating LL appears to be one of the key factors that mediates survival and successful proliferation of the parasite metacestode in vivo
Roles of NMDA and dopamine in food-foraging decision-making strategies of rats in the social setting
Leaf senescence and photosynthesis in foxtail millet [Setaria italica (L.) P. Beauv] varieties exposed to drought conditions
Abstract In this paper, we studied the changes of net photosynthetic rates (P n ), the contents of chlorophyll, soluble protein, malondialdehyde (MDA), superoxide radical (O 2 -· ), and hydrogen peroxide (H 2 O 2 ), and the activities of superoxide dismutase (SOD; EC1.15.1.1) and catalase (CAT; EC 1.11.1.6) in the leaves of two foxtail millet varieties (05-61 and Jingu3) under drought stress from 14 days after anthesis to maturity. P N , the contents of chlorophyll and soluble protein and the activities of SOD and CAT increased and then declined as the plants aged, whereas the accumulation of MDA, O 2 -· and H 2 O 2 gradually increased with senescence. Although the leaves of two varieties generally shared a similar pattern of senescence, their rates of aging differed. The activities of SOD and CAT in leaves of 05-61 declined more quickly than Jingu3, particularly in the late stages of grain filling. Taken together, the results implicated that the alleviation of leaf senescence played an important role in promoting grain filling and enhancing the yield and quality of 05-61 in the rain-fed agriculture area
Subtype distribution of lymphomas in Southwest China: Analysis of 6,382 cases using WHO classification in a single institution
<p>Abstract</p> <p>Background</p> <p>The subtype distribution of lymphoid neoplasms in Southwest China was analyzed according to WHO classifications. This study aims to analyze subtype distribution of lymphomas in southwest China.</p> <p>Methods</p> <p>Lymphoid neoplasms diagnosed within 9 years in a single institution in Southwest China were analyzed according to the WHO classification.</p> <p>Results</p> <p>From January 2000 to December 2008, a total number of 6,382 patients with lymphoma were established, of which mature B-cell neoplasms accounted for 56%, mature T- and NK-cell neoplasms occupied 26%, and precursor lymphoid neoplasms and Hodgkin lymphomas were 5% and 13%, respectively. Mixed cellularity (76%) was the major subtype of classical Hodgkin lymphoma; and the bimodal age distribution was not observed. The top six subtypes of non-Hodgkin lymphoma were as follows: diffuse large B-cell lymphoma, extranodal NK/T-cell lymphoma, nasal type, extranodal marginal zone lymphoma of mucosa associated lymphoid tissue, follicular lymphoma, precursor lymphoid neoplasms, and chronic lymphocytic leukemia/small lymphocytic lymphoma. Extranodal lymphomas comprised about half of all cases, and most frequently involved Waldeyer's ring, gastrointestinal tract, sinonasal region and skin.</p> <p>Conclusions</p> <p>The lymphoid neoplasms of Southwest China displayed some epidemiologic features similar to those reported in literature from western and Asian countries, as well as other regions of China, whereas some subtypes showed distinct features. The high frequency of mature T/NK cell neoplasms and extranodal lymphomas, especially for extranodal NK/T-cell lymphoma, nasal type, is the most outstanding characteristic of this series.</p
Relaxation of the one child policy and trends in caesarean section rates and birth outcomes in China between 2012 and 2016: observational study of nearly seven million health facility births.
OBJECTIVE: To examine how the relaxation of the one child policy and policies to reduce caesarean section rates might have affected trends over time in caesarean section rates and perinatal and pregnancy related mortality in China. DESIGN: Observational study. SETTING: China's National Maternal Near Miss Surveillance System (NMNMSS). PARTICIPANTS: 6â838â582 births at 28 completed weeks or more of gestation or birth weight â„1000 g in 438 hospitals in the NMNMSS between 2012 and 2016. MAIN OUTCOME MEASURES: Obstetric risk was defined using a modified Robson classification. The main outcome measures were changes in parity and age distributions and relative frequency of each Robson group, crude and adjusted trends over time in caesarean section rates within each risk category (using Poisson regression with a robust variance estimator), and trends in perinatal and pregnancy related mortality over time. RESULTS: Caesarean section rates declined steadily between 2012 and 2016 (crude relative risk 0.91, 95% confidence interval 0.89 to 0.93), reaching an overall hospital based rate of 41.1% in 2016. The relaxation of the one child policy was associated with an increase in the proportion of multiparous births (from 34.1% in 2012 to 46.7% in 2016), and births in women with a uterine scar nearly doubled (from 9.8% to 17.7% of all births). Taking account of these changes, the decline in caesarean sections was amplified over time (adjusted relative risk 0.82, 95% confidence interval 0.81 to 0.84). Caesarean sections declined noticeably in nulliparous women (0.75, 0.73 to 0.77) but also declined in multiparous women without a uterine scar (0.65, 0.62 to 0.77). The decrease in caesarean section rates was most pronounced in hospitals with the highest rates in 2012, consistent with the government's policy of targeting hospitals with the highest rates. Perinatal mortality declined from 10.1 to 7.2 per 1000 births over the same period (0.87, 0.83 to 0.91), and there was no change in pregnancy related mortality over time. CONCLUSIONS: China is the only country that has succeeded in reverting the rising trends in caesarean sections. China's success is remarkable given that the changes in obstetric risk associated with the relaxation of the one child policy would have led to an increase in the need for caesarean sections. China's experience suggests that change is possible when strategies are comprehensive and deal with the system level factors that underpin overuse as well as the various incentives at work during a clinical encounter
Isolation and characterization of drought-responsive genes from peanut roots by suppression subtractive hybridization
Background: Peanut ( Arachis hypogaea L.) is an important economic
and oilseed crop. Long-term rainless conditions and seasonal droughts
can limit peanut yields and were conducive to preharvest aflatoxin
contamination. To elucidate the molecular mechanisms by which peanut
responds and adapts to water limited conditions, we isolated and
characterized several drought-induced genes from peanut roots using a
suppression subtractive hybridization (SSH) technique. Results: RNA was
extracted frompeanut roots subjected to a water stress treatment (45%
field capacity) and from control plants (75% field capacity), and used
to generate an SSH cDNA library. A total of 111 non-redundant sequences
were obtained, with 80 unique transcripts showing homology to known
genes and 31 clones with no similarity to either hypothetical or known
proteins. GO and KEGG analyses of these differentially expressed ESTs
indicated that drought-related responses in peanut could mainly be
attributed to genes involved in cellular structure and metabolism. In
addition, we examined the expression patterns of seven differentially
expressed candidate genes using real-time reverse transcription-PCR
(qRT-PCR) and confirmed that all were up-regulated in roots in response
to drought stress, but to differing extents. Conclusions: We
successfully constructed an SSH cDNA library in peanut roots and
identified several drought-related genes. Our results serve as a
foundation for future studies into the elucidation of the drought
stress response mechanisms of peanut
Sociodemographic and obstetric characteristics of stillbirths in China: a census of nearly 4 million health facility births between 2012 and 2014
Background Very little is known about the burden and determinants of stillbirths in China. We used data from a
national surveillance system for health facility births to compute a stillbirth rate representative of all facility births in
China and to explore sociodemographic and obstetric factors associated with variation in the stillbirth rate.
Methods We used data from Chinaâs National Maternal Near Miss Surveillance System between Jan 1, 2012, and
Dec 31, 2014, which covers 441 hospitals in 326 urban districts and rural counties. The surveillance aimed to
enumerate all maternal deaths and near misses in health facilities, and collected data prospectively for all pregnant
or post-partum women admitted to the obstetric department. We restricted the analysis to births of 28 or more
completed weeks of gestation or 1000 g or heavier birthweight. We examined the strength of association between
sociodemographic characteristics, gestational age, and obstetric complications and stillbirths using logistic
regression, taking account of the sampling strategy and clustering of births within hospitals and in cases of more
than one birth per woman.
Findings There were 3 956 836 births and 37 855 stillbirths, giving a stillbirth rate of 8·8 per 1000 births (95% CI
8·8â8·9). The stillbirth rate was particularly high for women younger than 15 years of age (59·9 stillbirths
per 1000 births), those who had not sought antenatal care (38·3 per 1000), the unmarried (32·5 per 1000), those with
no education (26·9 per 1000), or those who had had four or more births (23·2 per 1000). A high proportion
(29 319 [78·2%] of 37 514) of stillbirths occurred at gestational ages of younger than 37 weeks, and about two thirds
(24 787 [66·1%] of 37 514) were in women without any maternal complication at the time of birth. Of babies born at
normal gestations (37â41 weeks), maternal complications substantially increased the risk of stillbirth (odds ratio
comparing antepartum or intrapartum complications with no complication 3·96 [95% CI 3·66â4·29]), but only a
small proportion (1638 [4·4%] of 37 514) of stillbirths fell into this group.
Interpretation Our analysis of nearly 4 million births in 441 health facilities in China suggests a stillbirth rate of
8·8 per 1000 births between 2012 and 2014. Stillbirths do not feature in the Chinese Governmentâs 5 year plans and
most information systems do not include stillbirths. The Government need to start paying attention to stillbirths and
invest strategically in antenatal care, particularly for the most disadvantaged women, including the very young,
unmarried, and illiterate, and those at high parity
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